Search Results - "Cantor, Rita M."

Transcriptomic analysis of autistic brain reveals convergent molecular pathology by Voineagu, Irina, Wang, Xinchen, Johnston, Patrick, Lowe, Jennifer K., Tian, Yuan, Horvath, Steve, Mill, Jonathan, Cantor, Rita M., Blencowe, Benjamin J., Geschwind, Daniel H.

“…A shared aetiology for autism? Despite high heritability, autism is genetically very heterogeneous. This raises the question of whether there are many…”
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Impact of Individual Traits, Saturated Fat, and Protein Source on the Gut Microbiome by Lang, Jennifer M, Pan, Calvin, Cantor, Rita M, Tang, W H Wilson, Garcia-Garcia, Jose Carlos, Kurtz, Ira, Hazen, Stanley L, Bergeron, Nathalie, Krauss, Ronald M, Lusis, Aldons J

“…Interindividual variation in the composition of the human gut microbiome was examined in relation to demographic and anthropometric traits, and to changes in…”
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Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS by Pan, David Z., Garske, Kristina M., Alvarez, Marcus, Bhagat, Yash V., Boocock, James, Nikkola, Elina, Miao, Zong, Raulerson, Chelsea K., Cantor, Rita M., Civelek, Mete, Glastonbury, Craig A., Small, Kerrin S., Boehnke, Michael, Lusis, Aldons J., Sinsheimer, Janet S., Mohlke, Karen L., Laakso, Markku, Pajukanta, Päivi, Ko, Arthur

“…Increased adiposity is a hallmark of obesity and overweight, which affect 2.2 billion people world-wide. Understanding the genetic and molecular mechanisms…”
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Genetic and hormonal control of hepatic steatosis in female and male mice by Norheim, Frode, Hui, Simon T, Kulahcioglu, Emre, Mehrabian, Margarete, Cantor, Rita M, Pan, Calvin, Parks, Brian W, Lusis, Aldons J

“…The etiology of nonalcoholic fatty liver disease is complex and influenced by factors such as obesity, insulin resistance, hyperlipidemia, and sex. We now…”
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Gut microbe-derived metabolites and the risk of cardiovascular disease in the METSIM cohort by Mirzaei, Sahereh, DeVon, Holli A, Cantor, Rita M, Cupido, Arjen, Fernandes Silva, Lilian, Laakso, Markku, Lusis, Aldons J

“…An association between gut microbes and cardiovascular disease (CVD) has been established, but the underlying mechanisms remain largely unknown. We conducted a…”
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Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus by Shen, Nan, Fu, Qiong, Deng, Yun, Qian, Xiaoxia, Zhao, Jian, Kaufman, Kenneth M., Wu, Yee Ling, Yu, C. Yung, Tang, Yuanjia, Chen, Ji-Yih, Yang, Wanling, Wong, Maida, Kawasaki, Aya, Tsuchiya, Naoyuki, Sumida, Takayuki, Kawaguchi, Yasushi, Howe, Hwee Siew, Mok, Mo Yin, Bang, So-Young, Liu, Fei-Lan, Chang, Deh-Ming, Takasaki, Yoshinari, Hashimoto, Hiroshi, Harley, John B., Guthridge, Joel M., Grossman, Jennifer M., Cantor, Rita M., Song, Yeong Wook, Bae, Sang-Cheol, Chen, Shunle, Hahn, Bevra H., Lau, Yu Lung, Tsao, Betty P., Smith, Kenneth G. C.

“…Systemic lupus erythematosus (SLE) is a multisystem, autoimmune disease that predominantly affects women. Previous findings that duplicated Toll-like receptor…”
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Transcriptome analysis in whole blood reveals increased microbial diversity in schizophrenia by Olde Loohuis, Loes M., Mangul, Serghei, Ori, Anil P. S., Jospin, Guillaume, Koslicki, David, Yang, Harry Taegyun, Wu, Timothy, Boks, Marco P., Lomen-Hoerth, Catherine, Wiedau-Pazos, Martina, Cantor, Rita M., de Vos, Willem M., Kahn, René S., Eskin, Eleazar, Ophoff, Roel A.

“…The role of the human microbiome in health and disease is increasingly appreciated. We studied the composition of microbial communities present in blood across…”
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Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants[S] by Lee, Jessica M., Ong, Jessica R., Vergnes, Laurent, de Aguiar Vallim, Thomas Q., Nolan, Jonathan, Cantor, Rita M., Walters, JulianR.F., Reue, Karen

“…Diet1 modulates intestinal production of the hormone, fibroblast growth factor (FGF)15, which signals in liver to regulate bile acid synthesis. C57BL/6ByJ mice…”
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Rare Inherited and De Novo CNVs Reveal Complex Contributions to ASD Risk in Multiplex Families by Leppa, Virpi M., Kravitz, Stephanie N., Martin, Christa Lese, Andrieux, Joris, Le Caignec, Cedric, Martin-Coignard, Dominique, DyBuncio, Christina, Sanders, Stephan J., Lowe, Jennifer K., Cantor, Rita M., Geschwind, Daniel H.

“…Rare mutations, including copy-number variants (CNVs), contribute significantly to autism spectrum disorder (ASD) risk. Although their importance has been…”
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Phosphodiesterase Genes Are Associated with Susceptibility to Major Depression and Antidepressant Treatment Response by Wong, Ma-Li, Whelan, Fiona, Deloukas, Panagiotis, Whittaker, Pamela, Delgado, Marcos, Cantor, Rita M., McCann, Samuel M., Licinio, Julio

“…Cyclic nucleotide phosphodiesterases (PDEs) constitute a family of enzymes that degrade cAMP and cGMP. Intracellular cyclic nucleotide levels increase in…”
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Genome-wide Linkage and Association Analyses Implicate FASN in Predisposition to Uterine Leiomyomata by EGGERT, Stacey L, HUYCK, Karen L, TRELOAR, Susan A, ZONDERVAN, Krina T, HEATH, Andrew C, MADDEN, Pamela A. F, ROSE, Lynda, BURING, JulieE, RIDKER, Paul M, CHASMAN, Daniel I, MARTIN, Nicholas G, CANTOR, Rita M, SOMASUNDARAM, Priya, MORTON, Cynthia C, KAVALLA, Raghava, STEWART, Elizabeth A, LU, Ake T, PAINTER, Jodie N, MONTGOMERY, Grant W, MEDLAND, Sarah E, NYHOLT, Dale R

“…Uterine leiomyomata (UL), the most prevalent pelvic tumors in women of reproductive age, pose a major public health problem given their high frequency,…”
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Support for calcium channel gene defects in autism spectrum disorders by Lu, Ake Tzu-Hui, Dai, Xiaoxian, Martinez-Agosto, Julian A, Cantor, Rita M

“…Alternation of synaptic homeostasis is a biological process whose disruption might predispose children to autism spectrum disorders (ASD). Calcium channel…”
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A Quantitative Trait Locus Analysis of Social Responsiveness in Multiplex Autism Families by Duvall, Jacqueline A., Lu, Ake, Cantor, Rita M., Todd, Richard D., Constantino, John N., Geschwind, Daniel H.

“…Objective: Autism is a complex genetic disorder with a highly heterogeneous phenotype defined by repetitive behaviors, language deficits, and problems with…”
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Relationships and Mendelian Randomization of Gut Microbe-Derived Metabolites with Metabolic Syndrome Traits in the METSIM Cohort by Mirzaei, Sahereh, DeVon, Holli A, Cantor, Rita M, Cupido, Arjen J, Pan, Calvin, Ha, Sung Min, Silva, Lilian Fernandes, Hilser, James R, Hartiala, Jaana, Allayee, Hooman, Rey, Federico E, Laakso, Markku, Lusis, Aldons J

“…The role of gut microbe-derived metabolites in the development of metabolic syndrome (MetS) remains unclear. This study aimed to evaluate the associations of…”
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Familial aggregation of hyperemesis gravidarum by Zhang, Yafeng, MS, Cantor, Rita M., PhD, MacGibbon, Kimber, RN, Romero, Roberto, MD, Goodwin, Thomas M., MD, Mullin, Patrick M., MD, MPH, Fejzo, Marlena S., PhD

“…Objective This study was undertaken to determine whether there is familial aggregation of hyperemesis gravidarum (HG), making it a disease amenable to genetic…”
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Genome-wide burden of deleterious coding variants increased in schizophrenia by Loohuis, Loes M. Olde, Vorstman, Jacob A. S., Ori, Anil P., Staats, Kim A., Wang, Tina, Richards, Alexander L., Leonenko, Ganna, Walters, James T., DeYoung, Joseph, Cantor, Rita M., Ophoff, Roel A.

“…Schizophrenia is a common complex disorder with polygenic inheritance. Here we show that by using an approach that compares the individual loads of rare…”
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Prioritizing GWAS Results: A Review of Statistical Methods and Recommendations for Their Application by Cantor, Rita M., Lange, Kenneth, Sinsheimer, Janet S.

“…Genome-wide association studies (GWAS) have rapidly become a standard method for disease gene discovery. A substantial number of recent GWAS indicate that for…”
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Genetic and hormonal control of hepatic steatosis in female and male mice1 by Norheim, Frode, Hui, Simon T., Kulahcioglu, Emre, Mehrabian, Margarete, Cantor, Rita M., Pan, Calvin, Parks, Brian W., Lusis, Aldons J.

“…The etiology of nonalcoholic fatty liver disease is complex and influenced by factors such as obesity, insulin resistance, hyperlipidemia, and sex. We now…”
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Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS by Pan, David Z., Garske, Kristina M., Alvarez, Marcus, Bhagat, Yash V., Boocock, James, Nikkola, Elina, Miao, Zong, Raulerson, Chelsea K., Cantor, Rita M., Civelek, Mete, Glastonbury, Craig A., Small, Kerrin S., Boehnke, Michael, Lusis, Aldons J., Sinsheimer, Janet S., Mohlke, Karen L., Laakso, Markku, Pajukanta, Päivi, Ko, Arthur

“…In the original version of this Article, Supplementary Table 10 contained incorrect primer sequences for the mobility shift assay for SNP rs4776984. These…”
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Anatomic brain asymmetry in vervet monkeys by Fears, Scott C, Scheibel, Kevin, Abaryan, Zvart, Lee, Chris, Service, Susan K, Jorgensen, Matthew J, Fairbanks, Lynn A, Cantor, Rita M, Freimer, Nelson B, Woods, Roger P

“…Asymmetry is a prominent feature of human brains with important functional consequences. Many asymmetric traits show population bias, but little is known about…”
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