Search Results - "Cantor, R M"

Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid by Luykx, J J, Bakker, S C, Lentjes, E, Neeleman, M, Strengman, E, Mentink, L, DeYoung, J, de Jong, S, Sul, J H, Eskin, E, van Eijk, K, van Setten, J, Buizer-Voskamp, J E, Cantor, R M, Lu, A, van Amerongen, M, van Dongen, E P A, Keijzers, P, Kappen, T, Borgdorff, P, Bruins, P, Derks, E M, Kahn, R S, Ophoff, R A

“…Studying genetic determinants of intermediate phenotypes is a powerful tool to increase our understanding of genotype–phenotype correlations. Metabolic traits…”
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Allowing for sex differences increases power in a GWAS of multiplex Autism families by Lu, A T-H, Cantor, R M

“…Current genomewide association studies account for only a small fraction of the estimated heritabilities of genetically complex neuropsychiatric disorders,…”
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QTL replication and targeted association highlight the nerve growth factor gene for nonverbal communication deficits in autism spectrum disorders by Lu, A T-H, Yoon, J, Geschwind, D H, Cantor, R M

“…Autism Spectrum Disorder (ASD) has a heterogeneous etiology that is genetically complex. It is defined by deficits in communication and social skills and the…”
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Quantitative genome scan and Ordered-Subsets Analysis of autism endophenotypes support language QTLs by ALARCON, M, YONAN, A. L, GILLIAM, T. C, CANTOR, R. M, GESCHWIND, D. H

“…Autism is a neurodevelopmental syndrome with early childhood onset and deficits in three behavioral and cognitive dimensions: language, social skills and…”
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High-density SNP association study of the 17q21 chromosomal region linked to autism identifies CACNA1G as a novel candidate gene by Strom, S P, Stone, J L, ten Bosch, J R, Merriman, B, Cantor, R M, Geschwind, D H, Nelson, S F

“…Chromosome 17q11-q21 is a region of the genome likely to harbor susceptibility to autism (MIM(209850)) based on earlier evidence of linkage to the disorder…”
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Evidence for linkage of a tandem duplication polymorphism upstream of the dopamine D4 receptor gene (DRD4) with attention deficit hyperactivity disorder (ADHD) by MCCRACKEN, J. T, SMALLEY, S. L, MCGOUGH, J. J, CRAWFORD, L, DEL'HOMME, M, CANTOR, R. M, LIU, A, NELSON, S. F

“…Attention deficit hyperactivity disorder (ADHD) is a common childhood-onset neurodevelopmental disorder. Evidence from twin, adoption, and family studies…”
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Paternal age and autism are associated in a family-based sample by CANTOR, R. M, YOON, J. L, FURR, J, LAJONCHERE, C. M

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Quantitative trait locus analysis of nonverbal communication in autism spectrum disorder by Chen, G K, Kono, N, Geschwind, D H, Cantor, R M

“…Autism spectrum disorder (ASD) is a neurodevelopmental syndrome marked by impairments in social interactive functioning and communication skills, and the…”
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Seasonal variation of serotonin turnover in human cerebrospinal fluid, depressive symptoms and the role of the 5-HTTLPR by Luykx, J J, Bakker, S C, van Geloven, N, Eijkemans, M J C, Horvath, S, Lentjes, E, Boks, M P M, Strengman, E, DeYoung, J, Buizer-Voskamp, J E, Cantor, R M, Lu, A, van Dongen, E P A, Borgdorff, P, Bruins, P, Kahn, R S, Ophoff, R A

“…Studying monoaminergic seasonality is likely to improve our understanding of neurobiological mechanisms underlying season-associated physiological and…”
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Septic shock and respiratory failure in community-acquired pneumonia have different TNF polymorphism associations by WATERER, Grant W, QUASNEY, Michael W, CANTOR, Rita M, WUNDERINK, Richard G

“…Genetic factors are likely to contribute to the variable presentation of community-acquired pneumonia (CAP). The purpose of this prospective cohort study was…”
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Family-based association analysis implicates IL-4 in susceptibility to Kawasaki disease by Burns, J C, Shimizu, C, Shike, H, Newburger, J W, Sundel, R P, Baker, A L, Matsubara, T, Ishikawa, Y, Brophy, V A, Cheng, S, Grow, M A, Steiner, L L, Kono, N, Cantor, R M

“…Several compelling lines of evidence suggest an important influence of genetic variation in susceptibility to Kawasaki disease (KD), an acute vasculitis that…”
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Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis by Gallagher, C. S., Mäkinen, N., Harris, H. R., Rahmioglu, N., Uimari, O., Cook, J. P., Shigesi, N., Ferreira, T., Velez-Edwards, D. R., Edwards, T. L., Mortlock, S., Ruhioglu, Z., Day, F., Becker, C. M., Karhunen, V., Martikainen, H., Järvelin, M.-R., Cantor, R. M., Ridker, P. M., Terry, K. L., Buring, J. E., Gordon, S. D., Medland, S. E., Montgomery, G. W., Nyholt, D. R., Hinds, D. A., Tung, J. Y., Perry, J. R. B., Lind, P. A., Painter, J. N., Martin, N. G., Morris, A. P., Chasman, D. I., Missmer, S. A., Zondervan, K. T., Morton, C. C.

“…Uterine leiomyomata (UL) are the most common neoplasms of the female reproductive tract and primary cause for hysterectomy, leading to considerable morbidity…”
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Pooled genome-wide linkage data on 424 ADHD ASPs suggests genetic heterogeneity and a common risk locus at 5p13 by Ogdie, M N, Bakker, S C, Fisher, S E, Francks, C, Yang, M H, Cantor, R M, Loo, S K, van der Meulen, E, Pearson, P, Buitelaar, J, Monaco, A, Nelson, S F, Sinke, R J, Smalley, S L

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Obesity and obesogenic growth are both highly heritable and modified by diet in a nonhuman primate model, the African green monkey (Chlorocebus aethiops sabaeus) by Schmitt, C A, Service, S K, Jasinska, A J, Dyer, T D, Jorgensen, M J, Cantor, R M, Weinstock, G M, Blangero, J, Kaplan, J R, Freimer, N B

“…Objective: In humans, the ontogeny of obesity throughout the life course and the genetics underlying it has been historically difficult to study. We compared,…”
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ASD restricted and repetitive behaviors associated at 17q21.33: genes prioritized by expression in fetal brains by Cantor, R M, Navarro, L, Won, H, Walker, R L, Lowe, J K, Geschwind, D H

“…Autism spectrum disorder (ASD) is a behaviorally defined condition that manifests in infancy or early childhood as deficits in communication skills and social…”
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Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse by King, Lily M, Ahmad, Wasim, Ahmad, Mahmud, Haque, Sayedul, Rusiniak, Michael E, Haque, Muhammad Faiyaz ul, Krakow, Deborah, Cantor, Rita M, Abbas, Hasan, Superti-Furga, Andrea, Swank, Richard T, Cohn, Daniel H

“…The osteochondrodysplasias are a genetically heterogeneous group of disorders affecting skeletal development, linear growth and the maintenance of cartilage…”
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Author Correction: Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis by Gallagher, C. S., Mäkinen, N., Harris, H. R., Rahmioglu, N., Uimari, O., Cook, J. P., Shigesi, N., Ferreira, T., Velez-Edwards, D. R., Edwards, T. L., Mortlock, S., Ruhioglu, Z., Day, F., Becker, C. M., Karhunen, V., Martikainen, H., Järvelin, M.-R., Cantor, R. M., Ridker, P. M., Terry, K. L., Buring, J. E., Gordon, S. D., Medland, S. E., Montgomery, G. W., Nyholt, D. R., Hinds, D. A., Tung, J. Y., Perry, J. R. B., Lind, P. A., Painter, J. N., Martin, N. G., Morris, A. P., Chasman, D. I., Missmer, S. A., Zondervan, K. T., Morton, C. C.

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Increased frequency of alleles associated with elevated tumor necrosis factor-α levels in children with Kawasaki disease by QUASNEY, Michael W, BRONSTEIN, David E, NEWBURGER, Jane W, BURNS, Jane C, CANTOR, Rita M, QING ZHANG, STROUPE, Courtney, SHIKE, Hiroko, BASTIAN, John F, MATSUBARA, Tomoyo, FUJIWARA, Motoki, AKIMOTO, Katsumi

“…Genetic polymorphisms influence the magnitude of the cytokine response after an inflammatory stimulus. To determine whether such polymorphisms might play a…”
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Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A by Kallen, C.J.H. van der, Cantor, R.M, Greevenbroek, M.M.J. van, Geurts, J.M.W, Bouwman, F.G, Aouizerat, B.E, Allayee, H, Buurman, W.A, Lusis, A.J, Rotter, J.I

“…OBJECTIVE: To search for novel genes contributing to adiposity in familial combined hyperlipidemia (FCH), a disorder characterized by abdominal obesity,…”
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A Genome Scan for Familial Combined Hyperlipidemia Reveals Evidence of Linkage with a Locus on Chromosome 11 by Aouizerat, Bradley E., Allayee, Hooman, Cantor, Rita M., Davis, Richard C., Lanning, Christopher D., Wen, Ping-Zi, Dallinga-Thie, Geesje M., de Bruin, Tjerk W.A., Rotter, Jerome I., Lusis, Aldons J.

“…Familial combined hyperlipidemia (FCHL) is a common familial lipid disorder characterized by a variable pattern of elevated levels of plasma cholesterol and/or…”
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