Search Results - "Cantone, Vincenza"

Giffonins J–P, Highly Hydroxylated Cyclized Diarylheptanoids from the Leaves of Corylus avellana Cultivar “Tonda di Giffoni” by Masullo, Milena, Cantone, Vincenza, Cerulli, Antonietta, Lauro, Gianluigi, Messano, Francesco, Russo, Gian Luigi, Pizza, Cosimo, Bifulco, Giuseppe, Piacente, Sonia

“…Two new diaryl ether heptanoids, giffonins J and K (1 and 2), along with five new diarylheptanoids, giffonins L–P (3–7), were isolated from a methanol extract…”
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Cyclic Diarylheptanoids from Corylus avellana Green Leafy Covers: Determination of Their Absolute Configurations and Evaluation of Their Antioxidant and Antimicrobial Activities by Cerulli, Antonietta, Lauro, Gianluigi, Masullo, Milena, Cantone, Vincenza, Olas, Beata, Kontek, Bogdan, Nazzaro, Filomena, Bifulco, Giuseppe, Piacente, Sonia

“…The methanol extract of the leafy covers of Corylus avellana, source of the Italian PGI (protected geographical indication) product “Nocciola di Giffoni”,…”
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Anti‐inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions by Maione, Francesco, Cantone, Vincenza, Pace, Simona, Chini, Maria Giovanna, Bisio, Angela, Romussi, Giovanni, Pieretti, Stefano, Werz, Oliver, Koeberle, Andreas, Mascolo, Nicola, Bifulco, Giuseppe

“…Background and Purpose The diterpenoids carnosol (CS) and carnosic acid (CA) from Salvia spp. exert prominent anti‐inflammatory activities but their molecular…”
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Discovery of new potent molecular entities able to inhibit mPGES-1 by Di Micco, Simone, Terracciano, Stefania, Cantone, Vincenza, Fischer, Katrin, Koeberle, Andreas, Foglia, Antonio, Riccio, Raffaele, Werz, Oliver, Bruno, Ines, Bifulco, Giuseppe

“…mPGES-1, a glutathione-dependent membrane protein is involved in the last step of PGE2 production and has been well recognized as a strategic target for the…”
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Novel benzoxanthene lignans that favorably modulate lipid mediator biosynthesis: A promising pharmacological strategy for anti-inflammatory therapy by Gerstmeier, Jana, Kretzer, Christian, Di Micco, Simone, Miek, Laura, Butschek, Hannah, Cantone, Vincenza, Bilancia, Rossella, Rizza, Roberta, Troisi, Fabiana, Cardullo, Nunzio, Tringali, Corrado, Ialenti, Armando, Rossi, Antonietta, Bifulco, Giuseppe, Werz, Oliver, Pace, Simona

“…[Display omitted] Lipid mediators (LM) encompass pro-inflammatory prostaglandins (PG) and leukotrienes (LT) but also specialized pro-resolving mediators (SPM)…”
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A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4‐Thiazolidinedione‐Based Molecules as New Dual mPGES‐1/5‐LO Inhibitors by Lauro, Gianluigi, Terracciano, Stefania, Cantone, Vincenza, Ruggiero, Dafne, Fischer, Katrin, Pace, Simona, Werz, Oliver, Bruno, Ines, Bifulco, Giuseppe

“…Dual inhibition of microsomal prostaglandin E2 synthase‐1 (mPGES‐1) and 5‐lipoxygenase (5‐LO), two key enzymes involved in pro‐inflammatory eicosanoid…”
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Identification of 2,4‐Dinitro‐Biphenyl‐Based Compounds as MAPEG Inhibitors by Di Micco, Simone, Terracciano, Stefania, Pierri, Martina, Cantone, Vincenza, Liening, Stefanie, König, Stefanie, Garscha, Ulrike, Hofstetter, Robert Klaus, Koeberle, Andreas, Werz, Oliver, Bruno, Ines, Bifulco, Giuseppe

“…We identified 2,4‐dinitro‐biphenyl‐based compounds as new inhibitors of leukotriene C4 synthase (LTC4S) and 5‐lipoxygenase‐activating protein (FLAP), both…”
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Discovery of 3-hydroxy-3-pyrrolin-2-one-based mPGES-1 inhibitors using a multi-step virtual screening protocol by Lauro, Gianluigi, Cantone, Vincenza, Potenza, Marianna, Fischer, Katrin, Koeberle, Andreas, Werz, Oliver, Riccio, Raffaele, Bifulco, Giuseppe

“…Targeting microsomal prostaglandin E synthase-1 (mPGES-1) represents an efficient strategy for the development of novel drugs against inflammation and cancer…”
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Identification of novel microsomal prostaglandin E 2 synthase-1 (mPGES-1) lead inhibitors from Fragment Virtual Screening by Lauro, Gianluigi, Manfra, Michele, Pedatella, Silvana, Fischer, Katrin, Cantone, Vincenza, Terracciano, Stefania, Bertamino, Alessia, Ostacolo, Carmine, Gomez-Monterrey, Isabel, De Nisco, Mauro, Riccio, Raffaele, Novellino, Ettore, Werz, Oliver, Campiglia, Pietro, Bifulco, Giuseppe

“…Identification of new microsomal prostaglandin E synthase-1 (mPGES-1) inhibitors is currently sought for the treatment of cancer and inflammation. Here we show…”
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Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E 2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation by Cheung, Sun-Yee, Werner, Markus, Esposito, Lucia, Troisi, Fabiana, Cantone, Vincenza, Liening, Stefanie, König, Stefanie, Gerstmeier, Jana, Koeberle, Andreas, Bilancia, Rossella, Rizza, Roberta, Rossi, Antonietta, Roviezzo, Fiorentina, Temml, Veronika, Schuster, Daniela, Stuppner, Hermann, Schubert-Zsilavecz, Manfred, Werz, Oliver, Hanke, Thomas, Pace, Simona

“…Leukotrienes (LTs) and prostaglandin (PG)E , produced by 5-lipoxygenase (5-LO) and microsomal prostaglandin E synthase-1 (mPGES-1), respectively, are key…”
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Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation by Cheung, Sun-Yee, Werner, Markus, Esposito, Lucia, Troisi, Fabiana, Cantone, Vincenza, Liening, Stefanie, König, Stefanie, Gerstmeier, Jana, Koeberle, Andreas, Bilancia, Rossella, Rizza, Roberta, Rossi, Antonietta, Roviezzo, Fiorentina, Temml, Veronika, Schuster, Daniela, Stuppner, Hermann, Schubert-Zsilavecz, Manfred, Werz, Oliver, Hanke, Thomas, Pace, Simona

“…Leukotrienes (LTs) and prostaglandin (PG)E2, produced by 5-lipoxygenase (5-LO) and microsomal prostaglandin E2 synthase-1 (mPGES-1), respectively, are key…”
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Discovery of 3-hydroxy-3-pyrrolin-2-one-based mPGES-1 inhibitors using a multi-step virtual screening protocolElectronic supplementary information (ESI) available. See DOI: 10.1039/c8md00497h by Lauro, Gianluigi, Cantone, Vincenza, Potenza, Marianna, Fischer, Katrin, Koeberle, Andreas, Werz, Oliver, Riccio, Raffaele, Bifulco, Giuseppe

“…Targeting microsomal prostaglandin E 2 synthase-1 (mPGES-1) represents an efficient strategy for the development of novel drugs against inflammation and cancer…”
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Discovery of 3-hydroxy-3-pyrrolin-2-one-based mPGES-1 inhibitors using a multi-step virtual screening protocol† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8md00497h by Lauro, Gianluigi, Cantone, Vincenza, Potenza, Marianna, Fischer, Katrin, Koeberle, Andreas, Werz, Oliver, Riccio, Raffaele, Bifulco, Giuseppe

“…Virtual screening is a useful tool for disclosing new chemical species able to inhibit mPGES-1. Targeting microsomal prostaglandin E 2 synthase-1 (mPGES-1)…”
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Identification of novel microsomal prostaglandin E2 synthase-1 (mPGES-1) lead inhibitors from Fragment Virtual Screening by Lauro, Gianluigi, Manfra, Michele, Pedatella, Silvana, Fischer, Katrin, Cantone, Vincenza, Terracciano, Stefania, Bertamino, Alessia, Ostacolo, Carmine, Gomez-Monterrey, Isabel, De Nisco, Mauro, Riccio, Raffaele, Novellino, Ettore, Werz, Oliver, Campiglia, Pietro, Bifulco, Giuseppe

“…Identification of new microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors is currently sought for the treatment of cancer and inflammation. Here we…”
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Molecular mechanism of tanshinone IIA and cryptotanshinone in platelet anti-aggregating effects: an integrated study of pharmacology and computational analysis by Maione, Francesco, Cantone, Vincenza, Chini, Maria Giovanna, De Feo, Vincenzo, Mascolo, Nicola, Bifulco, Giuseppe

“…Tanshinone IIA and cryptotanshinone are two pharmacologically active diterpenoids extracted from the roots of Salvia milthiorriza Bunge, a plant used in…”
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