Search Results - "Cantante, Mariana"

m6A RNA modification and its writer/reader VIRMA/YTHDF3 in testicular germ cell tumors: a role in seminoma phenotype maintenance by Lobo, João, Costa, Ana Laura, Cantante, Mariana, Guimarães, Rita, Lopes, Paula, Antunes, Luís, Braga, Isaac, Oliveira, Jorge, Pelizzola, Mattia, Henrique, Rui, Jerónimo, Carmen

“…Background Covalent RNA modifications, such as N-6-methyladenosine (m.sup.6A), have been associated with various biological processes, but their role in cancer…”
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Germ cell tumour subtypes display differential expression of microRNA371a-3p by Vilela-Salgueiro, Bárbara, Barros-Silva, Daniela, Lobo, João, Costa, Ana Laura, Guimarães, Rita, Cantante, Mariana, Lopes, Paula, Braga, Isaac, Oliveira, Jorge, Henrique, Rui, Jerónimo, Carmen

“…Testicular germ cell tumours (TGCTs) are a heterogeneous group of neoplasms, mostly affecting young men. Curability rates are high and adequate treatment…”
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Overexpression of circulating MiR-30b-5p identifies advanced breast cancer by Estevão-Pereira, Helena, Lobo, João, Salta, Sofia, Amorim, Maria, Lopes, Paula, Cantante, Mariana, Reis, Berta, Antunes, Luís, Castro, Fernando, Palma de Sousa, Susana, Gonçalves, Céline S., Costa, Bruno Marques, Henrique, Rui, Jerónimo, Carmen

“…Breast cancer (BrC) remains the leading cause of cancer-related death in women, mainly due to recurrent and/or metastatic events, entailing the need for…”
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Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors by Lobo, João, Constâncio, Vera, Guimarães‐Teixeira, Catarina, Leite‐Silva, Pedro, Miranda‐Gonçalves, Vera, Sequeira, José Pedro, Pistoni, Laura, Guimarães, Rita, Cantante, Mariana, Braga, Isaac, Maurício, Joaquina, Looijenga, Leendert H. J., Henrique, Rui, Jerónimo, Carmen

“…Testicular germ cell tumors (TGCTs) are the most common cancers in men aged 15–39 years and are divided into two major groups, seminomas and nonseminomas…”
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The component of the m6A writer complex VIRMA is implicated in aggressive tumor phenotype, DNA damage response and cisplatin resistance in germ cell tumors by Miranda-Gonçalves, Vera, Lobo, João, Guimarães-Teixeira, Catarina, Barros-Silva, Daniela, Guimarães, Rita, Cantante, Mariana, Braga, Isaac, Maurício, Joaquina, Oing, Christoph, Honecker, Friedemann, Nettersheim, Daniel, Looijenga, Leendert H. J, Henrique, Rui, Jerónimo, Carmen

“…Background Germ cell tumors (GCTs) are developmental cancers, tightly linked to embryogenesis and germ cell development. The recent and expanding field of RNA…”
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Cadherin switches during epithelial-mesenchymal transition: CDH4/RCAD downregulation reduces bladder cancer progression by Martins-Lima, Cláudia, Miranda-Gonçalves, Vera, Lobo, João, Constâncio, Vera, Leite-Silva, Pedro, Guimarães-Teixeira, Catarina, Monteiro-Reis, Sara, Sequeira, José Pedro, Cantante, Mariana, Gonçalves, Céline S., Costa, Bruno M., Henrique, Rui, Jerónimo, Carmen

“…Purpose Non-muscle invasive bladder cancer (NMIBC) is a highly recurrent disease that progresses to muscle-invasive bladder cancer (MIBC) in 5–25% of the…”
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Ki67 and LSD1 Expression in Testicular Germ Cell Tumors Is Not Associated with Patient Outcome: Investigation Using a Digital Pathology Algorithm by Lourenço, Beatriz Chaves, Guimarães-Teixeira, Catarina, Flores, Bianca C T, Miranda-Gonçalves, Vera, Guimarães, Rita, Cantante, Mariana, Lopes, Paula, Braga, Isaac, Maurício, Joaquina, Jerónimo, Carmen, Henrique, Rui, Lobo, João

“…TGCTs represent a model of curable disease afflicting especially young men. Defining tumor biological characteristics is crucial to increase current knowledge…”
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Detailed bladder cancer immunoprofiling reveals new clues for immunotherapeutic strategies by Viveiros, Nicole, Flores, Bianca CT, Lobo, João, Martins‐Lima, Cláudia, Cantante, Mariana, Lopes, Paula, Deantonio, Cecilia, Palu, Cintia, Sainson, Richard CA, Henrique, Rui, Jerónimo, Carmen

“…Objectives Bladder cancer (BlCa) is the tenth most frequent malignancy worldwide and the costliest to treat and monitor. Muscle‐invasive BlCa (MIBC) has a…”
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Testicular germ cell tumors: revisiting a series in light of the new WHO classification and AJCC staging systems, focusing on challenges for pathologists by Lobo, João, Costa, Ana Laura, Vilela-Salgueiro, Bárbara, Rodrigues, Ângelo, Guimarães, Rita, Cantante, Mariana, Lopes, Paula, Antunes, Luís, Jerónimo, Carmen, Henrique, Rui

“…Testicular germ cell tumors (TGCTs) are strikingly heterogeneous, reflecting a complex tumor model, posing serious challenges for pathologists. Accurate…”
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Detailed Characterization of Immune Cell Infiltrate and Expression of Immune Checkpoint Molecules PD-L1/CTLA-4 and MMR Proteins in Testicular Germ Cell Tumors Disclose Novel Disease Biomarkers by Lobo, João, Rodrigues, Ângelo, Guimarães, Rita, Cantante, Mariana, Lopes, Paula, Maurício, Joaquina, Oliveira, Jorge, Jerónimo, Carmen, Henrique, Rui

“…The immune infiltrate plays an important part in testicular germ cell tumors, but it remains scarcely studied. We aimed at thoroughly characterizing the immune…”
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Profiling the Adrenergic System in Breast Cancer and the Development of Metastasis by Sousa, Daniela M, Fernandes, Veronica, Lourenço, Catarina, Carvalho-Maia, Carina, Estevão-Pereira, Helena, Lobo, João, Cantante, Mariana, Couto, Marina, Conceição, Francisco, Jerónimo, Carmen, Pereira, Luisa, Lamghari, Meriem

“…Epidemiological studies and preclinical models suggest that chronic stress might accelerate breast cancer (BC) growth and the development of metastasis via…”
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DNA methylation profiling as a tool for testicular germ cell tumors subtyping by Costa, Ana L, Moreira-Barbosa, Catarina, Lobo, João, Vilela-Salgueiro, Bárbara, Cantante, Mariana, Guimarães, Rita, Lopes, Paula, Braga, Isaac, Oliveira, Jorge, Antunes, Luís, Henrique, Rui, Jerónimo, Carmen

“…Assess differential patterns of selected five genes' promoter methylation among testicular germ cell tumors (TGCT) subtypes. , , , and promoter methylation…”
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Germ cell tumour subtypes display differential expression of microRNA371a-3p by Vilela-Salgueiro, Bárbara, Barros-Silva, Daniela, Lobo, João, Costa, Ana Laura, Guimarães, Rita, Cantante, Mariana, Lopes, Paula, Braga, Isaac, Oliveira, Jorge, Henrique, Rui, Jerónimo, Carmen

“…Testicular germ cell tumours (TGCTs) are a heterogeneous group of neoplasms, mostly affecting young men. Curability rates are high and adequate treatment…”
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Efficacy of HDAC Inhibitors Belinostat and Panobinostat against Cisplatin-Sensitive and Cisplatin-Resistant Testicular Germ Cell Tumors by Lobo, João, Guimarães-Teixeira, Catarina, Barros-Silva, Daniela, Miranda-Gonçalves, Vera, Camilo, Vânia, Guimarães, Rita, Cantante, Mariana, Braga, Isaac, Maurício, Joaquina, Oing, Christoph, Honecker, Friedemann, Nettersheim, Daniel, Looijenga, Leendert H. J., Henrique, Rui, Jerónimo, Carmen

“…Novel treatment options are needed for testicular germ cell tumor (TGCT) patients, particularly important for those showing or developing cisplatin resistance,…”
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p53 and MDM2 expression in primary and metastatic testicular germ cell tumors: Association with clinical outcome by Lobo, João, Alzamora, Maria Ana, Guimarães, Rita, Cantante, Mariana, Lopes, Paula, Braga, Isaac, Maurício, Joaquina, Jerónimo, Carmen, Henrique, Rui

“…Background Testicular germ cell tumors (TGCTs) are highly sensitive to platinum‐based chemotherapy, and wild‐type p53 seems to play a pivotal role in this…”
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XIST -Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality by Lobo, João, Nunes, Sandra P, Gillis, Ad J M, Barros-Silva, Daniela, Miranda-Gonçalves, Vera, Berg, Annette van den, Cantante, Mariana, Guimarães, Rita, Henrique, Rui, Jerónimo, Carmen, Looijenga, Leendert H J

“…The event of X chromosome inactivation induced by , which is physiologically observed in females, is retained in testicular germ cell tumors (TGCTs), as a…”
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Differential methylation EPIC analysis discloses cisplatin-resistance related hypermethylation and tumor-specific heterogeneity within matched primary and metastatic testicular germ cell tumor patient tissue samples by Lobo, João, Constâncio, Vera, Leite-Silva, Pedro, Guimarães, Rita, Cantante, Mariana, Braga, Isaac, Maurício, Joaquina, Looijenga, Leendert H J, Henrique, Rui, Jerónimo, Carmen

“…Testicular germ cell tumors (TGCTs) are among the most common solid malignancies in young-adult men, and currently most mortality is due to metastatic disease…”
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Differential expression of DNA methyltransferases and demethylases among the various testicular germ cell tumor subtypes by Lobo, João, Guimarães, Rita, Miranda-Gonçalves, Vera, Monteiro-Reis, Sara, Cantante, Mariana, Antunes, Luís, Braga, Isaac, Maurício, Joaquina, Looijenga, Leendert Hj, Jerónimo, Carmen, Henrique, Rui

“…Characterize DNA methyltransferases/demethylases expression in testicular germ cell tumors (TGCTs). analysis of TCGA database, assessment of transcript levels…”
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The component of the m 6 A writer complex VIRMA is implicated in aggressive tumor phenotype, DNA damage response and cisplatin resistance in germ cell tumors by Miranda-Gonçalves, Vera, Lobo, João, Guimarães-Teixeira, Catarina, Barros-Silva, Daniela, Guimarães, Rita, Cantante, Mariana, Braga, Isaac, Maurício, Joaquina, Oing, Christoph, Honecker, Friedemann, Nettersheim, Daniel, Looijenga, Leendert H J, Henrique, Rui, Jerónimo, Carmen

“…Germ cell tumors (GCTs) are developmental cancers, tightly linked to embryogenesis and germ cell development. The recent and expanding field of RNA…”
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RAD51B me Levels as a Potential Predictive Biomarker for PD-1 Blockade Response in Non-Small Cell Lung Cancer by Guerreiro, Inês Maria, Barros-Silva, Daniela, Lopes, Paula, Cantante, Mariana, Cunha, Ana Luísa, Lobo, João, Antunes, Luís, Rodrigues, Ana, Soares, Marta, Henrique, Rui, Jerónimo, Carmen

“…Lung cancer (LC) cells frequently express high levels of programmed death-ligand 1 (PD-L1). Although these levels grossly correlate with the likelihood of…”
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