Search Results - "Cantù, G."

Head and neck soft tissue sarcomas: prognostic factors and outcome in a series of patients treated at a single institution by Mattavelli, D., Miceli, R., Radaelli, S., Mattavelli, F., Cantù, G., Barisella, M., Quattrone, P., Stacchiotti, S., Sangalli, C., Casali, P.G., Gronchi, A., Fiore, M.

“…Head and neck soft tissue sarcomas (STS) represent a rare disease. One hundred and sixty-seven patients underwent surgery at our institution with an…”
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Conservative management of early-stage epithelial ovarian cancer: results of a large retrospective series by Fruscio, R., Corso, S., Ceppi, L., Garavaglia, D., Garbi, A., Floriani, I., Franchi, D., Cantù, M.G., Bonazzi, C.M., Milani, R., Mangioni, C., Colombo, N.

“…To assess the long-term oncological outcome and the fertility of young women with early-stage epithelial ovarian cancer (ES/EOC) treated with fertility-sparing…”
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Prediction of TP53 Status for Primary Cisplatin, Fluorouracil, and Leucovorin Chemotherapy in Ethmoid Sinus Intestinal-Type Adenocarcinoma by LICITRA, L, SUARDI, S, PIEROTTI, M. A, PILOTTI, S, BOSSI, P, LOCATI, L. D, MARIANI, L, QUATTRONE, P, LO VULLO, S, OGGIONNI, M, OLMI, P, CANTA, G

“…To assess the role of TP53 status in predicting pathologic complete remission after primary chemotherapy in patients with ethmoidal intestinal-type…”
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A Non-Heme Diiron Complex for (Electro)catalytic Reduction of Dioxygen: Tuning the Selectivity through Electron Delivery by Wang, Lianke, Gennari, Marcello, Cantú Reinhard, Fabián G, Gutiérrez, Javier, Morozan, Adina, Philouze, Christian, Demeshko, Serhiy, Artero, Vincent, Meyer, Franc, de Visser, Sam P, Duboc, Carole

“…In the oxygen reduction reaction (ORR) domain, the investigation of new homogeneous catalysts is a crucial step toward the full comprehension of the key…”
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Baseline characteristics of cancer Patients demanding integrative oncology (IO) support. The experience of Nuova Oncologia Integrata (NOI), an Italian non-profit organization by Bidin, L., Marafante, G., Pellacani, B., Andreoni, A., Macca, G., Fiocchi, E., Boni, L., Cantù, G., Garnerone, L., Sgorbati, R., Putignano, F., Belfiglio, B., Franchi, F., Corda, C., La Guzza, C., Ferri, C., Giuffredi, I., Lamanuzzi, E., Pigaiani, L., Casini, M., Mazzoni, M.

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Randomized Controlled Trial of Single-Agent Paclitaxel Versus Cyclophosphamide, Doxorubicin, and Cisplatin in Patients With Recurrent Ovarian Cancer Who Responded to First-Line Platinum-Based Regimens by Cantu, M. G.

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Keto–Enol Tautomerization Triggers an Electrophilic Aldehyde Deformylation Reaction by a Nonheme Manganese(III)-Peroxo Complex by Cantú Reinhard, Fabián G, Barman, Prasenjit, Mukherjee, Gourab, Kumar, Jitendra, Kumar, Deep, Kumar, Devesh, Sastri, Chivukula V, de Visser, Sam P

“…Oxygen atom transfer by high-valent enzymatic intermediates remains an enigma in chemical catalysis. In particular, manganese is an important first-row metal…”
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Substrate Sulfoxidation by an Iron(IV)-Oxo Complex: Benchmarking Computationally Calculated Barrier Heights to Experiment by Cantú Reinhard, Fabián G, Faponle, Abayomi S, de Visser, Sam P

“…High-valent metal-oxo oxidants are common reactive species in synthetic catalysts as well as heme and nonheme iron enzymes. In general, they efficiently react…”
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Singlet versus Triplet Reactivity in an Mn(V)–Oxo Species: Testing Theoretical Predictions Against Experimental Evidence by Yang, Tzuhsiung, Quesne, Matthew G, Neu, Heather M, Cantú Reinhard, Fabián G, Goldberg, David P, de Visser, Sam P

“…Discerning the factors that control the reactivity of high-valent metal–oxo species is critical to both an understanding of metalloenzyme reactivity and…”
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Patients' survival after free flap reconstructive surgery of head and neck squamous cell carcinoma: a retrospective multicentre study by Salvatori, P, Paradisi, S, Calabrese, L, Zani, A, Cantù, G, Cappiello, J, Benazzo, M, Bozzetti, A, Bellocchi, G, Rinaldi Ceroni, A, Succo, G, Pastore, A, Chiesa, F, Riccio, S, Piazza, C, Occhini, A, Sozzi, D, Damiani, V, Caliceti, U, Crosetti, E, Pelucchi, S, Squadrelli Saraceno, M, Podrecca, S

“…Head and neck squamous cell carcinoma of the (HNSCC) represents approximately 5% of malignant tumours in Italy. HNSCC are commonly treated with surgery or…”
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A complete remission with androgen-deprivation therapy in a recurrent androgen receptor-expressing adenocarcinoma of the parotid gland by Locati, L. D., Quattrone, P., Bossi, P., Marchianò, A. V., Cantù, G, Licitra, L.

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Bioengineering of Cytochrome P450 OleTJE: How Does Substrate Positioning Affect the Product Distributions? by Cantú Reinhard, Fabián G., Lin, Yen-Ting, Stańczak, Agnieszka, de Visser, Sam P.

“…The cytochromes P450 are versatile enzymes found in all forms of life. Most P450s use dioxygen on a heme center to activate substrates, but one class of P450s…”
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Review of 346 patients with free-flap reconstruction following head and neck surgery for neoplasm by Podrecca, S., Salvatori, P., Saraceno, M. Squadrelli, Fallahdar, D., Calabrese, L., Cantù, G., Molinari, R.

“…We present our 14-year experience of free tissue transfer following surgery for head and neck neoplasm. We evaluated 346 patients mean age 57 years, 65% had…”
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The Equatorial Ligand Effect on the Properties and Reactivity of Iron(V) Oxo Intermediates by Pattanayak, Santanu, Cantú Reinhard, Fabián G., Rana, Atanu, Gupta, Sayam Sen, de Visser, Sam P.

“…High‐valent metal oxo oxidants are common catalytic‐cycle intermediates in enzymes and known to be highly reactive. To understand which features of these…”
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Hydrogen by Deuterium Substitution in an Aldehyde Tunes the Regioselectivity by a Nonheme Manganese(III)–Peroxo Complex by Barman, Prasenjit, Cantú Reinhard, Fabián G., Bagha, Umesh Kumar, Kumar, Devesh, Sastri, Chivukula V., de Visser, Sam P.

“…Mononuclear nonheme MnIII‐peroxo complexes are important intermediates in biology, and take part in oxygen activation by photosystem II. Herein, we present…”
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A Systematic Account on Aromatic Hydroxylation by a Cytochrome P450 Model Compound I: A Low-Pressure Mass Spectrometry and Computational Study by Cantú Reinhard, Fabián G., Sainna, Mala A., Upadhyay, Pranav, Balan, G. Alex, Kumar, Devesh, Fornarini, Simonetta, Crestoni, Maria Elisa, de Visser, Sam P.

“…Cytochrome P450 enzymes are heme‐containing mono‐oxygenases that mainly react through oxygen‐atom transfer. Specific features of substrate and oxidant that…”
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Oxygen Atom Transfer Using an Iron(IV)‐Oxo Embedded in a Tetracyclic N‐Heterocyclic Carbene System: How Does the Reactivity Compare to Cytochrome P450 Compound I? by Cantú Reinhard, Fabián G, de Visser, Sam P

“…N‐Heterocyclic carbenes (NHC) are commonly featured as ligands in transition metal catalysis. Recently, a cyclic system containing four NHC groups with a…”
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Mechanistic Studies of Fatty Acid Activation by CYP152 Peroxygenases Reveal Unexpected Desaturase Activity by Pickl, Mathias, Kurakin, Sara, Cantú Reinhard, Fabián G, Schmid, Philipp, Pöcheim, Alexander, Winkler, Christoph K, Kroutil, Wolfgang, de Visser, Sam P, Faber, Kurt

“…The majority of cytochrome P450 enzymes (CYPs) predominantly operate as monooxygenases, but recently a class of P450 enzymes was discovered, that can act as…”
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Solvent‐ and Halide‐Induced (Inter)conversion between Iron(II)‐Disulfide and Iron(III)‐Thiolate Complexes by Wang, Lianke, Cantú Reinhard, Fabián G., Philouze, Christian, Demeshko, Serhiy, de Visser, Sam P., Meyer, Franc, Gennari, Marcello, Duboc, Carole

“…Disulfide/thiolate interconversion controlled by Cu is proposed to be involved in relevant biological processes. In analogy to Cu, it can be envisaged that Fe…”
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Intraarterial chemotherapy with polyoxyethylated castor oil free paclitaxel, incorporated in albumin nanoparticles (ABI-007). Phase I study of patients with squamous cell carcinoma of the head and neck and anal canal: preliminary evidence of clinical activity by DAMASCELLI, Bruno, CANTU, Giulio, GARBAGNATI, Francesco, LANOCITA, Rodolfo, MARCHIANO, Alfonso, PATELLI, Gianluigi, SPREAFICO, Carlo, TICHA, Vladimira, VESPRO, Valentina, ZUNINO, Franco, MATTAVELLI, Franco, TAMPLENIZZA, Paolo, BIDOLI, Paolo, LEO, Ermanno, DOSIO, Franco, CERROTTA, Anna M, DI TOLLA, Giuseppe, FRIGERIO, Laura F

“…This study was designed to determine the feasibility, maximum tolerated dose, and toxicities of intraarterial administration of paclitaxel-albumin…”
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