Search Results - "Cant, Natasha"
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Detergent-free purification of ABC (ATP-binding-cassette) transporters
Published in Biochemical journal (15-07-2014)“…ABC (ATP-binding-cassette) transporters carry out many vital functions and are involved in numerous diseases, but study of the structure and function of these…”
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Journal Article -
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Detection of phospho-sites generated by protein kinase CK2 in CFTR: mechanistic aspects of Thr1471 phosphorylation
Published in PloS one (18-09-2013)“…By mass spectrometry analysis of mouse Cystic Fibrosis Transmembrane-conductance Regulator (mCFTR) expressed in yeast we have detected 21 phosphopeptides…”
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Systematic evaluation of PAXgene® tissue fixation for the histopathological and molecular study of lung cancer
Published in The journal of pathology. Clinical research (01-01-2020)“…Whilst adequate for most existing pathological tests, formalin is generally considered a poor DNA preservative and use of alternative fixatives may prove…”
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Structure of the cystic fibrosis transmembrane conductance regulator in the inward-facing conformation revealed by single particle electron microscopy
Published in AIMS biophysics (01-01-2015)“…The most common inherited disease in European populations is cystic fibrosis. Mutations in the gene lead to loss of function of the cystic fibrosis…”
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Journal Article -
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CFTR structure and cystic fibrosis
Published in The international journal of biochemistry & cell biology (01-07-2014)“…CFTR (cystic fibrosis transmembrane conductance regulator) is a member of the ATP-binding cassette family of membrane proteins. Although almost all members of…”
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Abstract 2745: Evaluation of a new system for collection, stabilization, and purification of circulating tumor DNA
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Introduction: The current preanalytical workflows for circulating tumor DNA (ctDNA) analysis have limitations that affect the accurate detection and…”
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Journal Article -
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Purification of the cystic fibrosis transmembrane conductance regulator protein expressed in Saccharomyces cerevisiae
Published in Journal of visualized experiments (10-05-2014)“…Defects in the cystic fibrosis transmembrane conductance regulator (CFTR) protein cause cystic fibrosis (CF), an autosomal recessive disease that currently…”
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A survey of detergents for the purification of stable, active human cystic fibrosis transmembrane conductance regulator (CFTR)
Published in Biochimica et biophysica acta. Biomembranes (01-11-2014)“…Structural knowledge of the cystic fibrosis transmembrane conductance regulator (CFTR) requires developing methods to purify and stabilize this…”
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Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein Expressed in Saccharomyces cerevisiae
Published in Journal of visualized experiments (10-05-2014)Get full text
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Expression and Purification of the Cystic Fibrosis Transmembrane Conductance Regulator From Saccharomyces cerevisiae for High-Resolution Structural Studies
Published 01-01-2014“…The cystic fibrosis transmembrane conductance regulator (CFTR) is an ABC transporter family protein that acts as an ion channel. Mutations in CFTR cause the…”
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Dissertation -
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Expression and purification of the cystic fibrosis transmembrane conductance regulator protein in Saccharomyces cerevisiae
Published in Journal of visualized experiments (10-03-2012)“…The cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride channel, that when mutated, can give rise to cystic fibrosis in humans.There is…”
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Journal Article -
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Expression and Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein in Saccharomyces cerevisiae
Published in Journal of visualized experiments (10-03-2012)Get full text
Journal Article