Search Results - "Cano, JP"

Study of the influence of water vapour and carbon dioxide dilution on pollutants emitted by swirled methane/oxygen-enriched air flames by Vandel, A., Chica Cano, J.P., de Persis, S., Cabot, G.

“…•H2O and CO2 dilution affects pollutant emissions in O2-enriched methane flames.•NOx, CO, CO2 and O2 emissions are measured by a HORIBA PG250 analyser.•N2 to…”
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Increased cytotoxicity and bystander effect of 5-fluorouracil and 5 -deoxy-5-fluorouridine in human colorectal cancer cells transfected with thymidine phosphorylase by EVRARD, A, CUQ, P, CICCOLINI, J, VIAN, L, CANO, J.-P

“…5-Fluorouracil (5-FU) and 5'-deoxy-5-fluorouridine (5'-DFUR), a prodrug of 5-FU, are anticancer agents activated by thymidine phosphorylase (TP). Transfecting…”
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Ultraviolet AI exposure of human skin results in Langerhans cell depletion and reduction of epidermal antigen-presenting cell function: partial protection by a broad-spectrum sunscreen by Dumay, O., Karam, A., Vian, L., Moyal, D., Hourseau, C., Stoebner, P., Peyron, J.L., Meynadier, J., Cano, J.P., Meunier, L.

“…Background Ultraviolet (UV) B‐induced effects on the skin immune system have been extensively investigated, but little is known regarding the immunological…”
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Transient protection by peripheral benzodiazepine receptors during the early events of ultraviolet light-induced apoptosis by Stoebner, P E, Carayon, P, Casellas, P, Portier, M, Lavabre-Bertrand, T, Cuq, P, Cano, J P, Meynadier, J, Meunier, L

“…The peripheral benzodiazepine receptor (PBR) is a mitochondrial protein involved in the formation of mitochondrial permeability transition (PT) pores which…”
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An attempt to determine the true stress-strain curves of amorphous polymers by nanoindentation by Hochstetter, G., Jimenez, A., Cano, J.P., Felder, E.

“…We have made an attempt to identify the true material stress-strain curves of some amorphous polymers (PC, PMMA, CR39 (diethylene glycol bis(allyl carbonate))…”
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Combination of thymidine phosphorylase gene transfer and deoxyinosine treatment greatly enhances 5-fluorouracil antitumor activity in vitro and in vivo by Ciccolini, J, Cuq, P, Evrard, A, Giacometti, S, Pelegrin, A, Aubert, C, Cano, J P, Iliadis, A

“…We reported previously that 5-fluorouracil (FUra) efficacy could be enhanced by increasing tumoral thymidine phosphorylase (TP) activity. Potentiated TP yield…”
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Immunosuppression induced by acute solar-simulated ultraviolet exposure in humans: Prevention by a sunscreen with a sun protection factor of 15 and high UVA protection by Serre, Isabelle, Cano, Jean Paul, Picot, Marie-Christine, Meynadier, Jean, Meunier, Laurent

“…Background: Cutaneous exposure to UVB radiation impairs the induction of contact hypersensitivity (CHS). Variable results have been found among studies…”
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In vitro detection of indirect-acting genotoxins in the comet assay using Hep G2 cells by Yusuf, Ayda Trisnawaty, Vian, Laurence, Sabatier, Robert, Cano, Jean-Paul

“…The induction of DNA damage by four known promutagens (cyclophosphamide (CP), benzo( a)pyrene (BP), dimethylbenz( a)anthracene and 2-acetylaminofluorene (2AAF)…”
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The expression of peripheral benzodiazepine receptors in human skin: the relationship with epidermal cell differentiation by STOEBNER, P. E, CARAYON, P, PENARIER, G, FRECHIN, N, BARNEON, G, CASELLAS, P, CANO, J. P, MEYNADIER, J, MEUNIER, L

“…The peripheral benzodiazepine receptor (PBR) is a protein of mitochondrial outer membranes utilizing porphyrins as endogenous ligands. PBR is part of a…”
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Fluoropyrimidine sensitivity of human MCF-7 breast cancer cells stably transfected with human uridine phosphorylase by CUQ, P, ROUQUET, C, EVRARD, A, CICCOLINI, J, VIAN, L, CANO, J-P

“…The relationship between uridine phosphorylase (UP) expression level in cancer cells and the tumour sensitivity to fluoropyrimidines is unclear. In this study,…”
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The Liverbeads® as a tool for the comet assay by Vian, Laurence, Yusuf, Ayda Trismawaty, Guyomard, Claire, Cano, Jean-Paul

“…Liverbeads®, cryopreserved hepatocytes entrapped within an alginate matrix, were examined for their relevance in the comet assay. It was estimated by their…”
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Postweaning multisystemic wasting syndrome in pigs in Venezuela by Cano, J. P., Rodríguez-Cariño, C., Sogbe, E., Utrera, V., Díaz, C. T., Segalés, J., Olvera, A., Calsamiglia, M.

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Characterization of midazolam metabolism using human hepatic microsomal fractions and hepatocytes in suspension obtained by perfusing whole human livers by Fabre, G, Rahmani, R, Placidi, M, Combalbert, J, Covo, J, Cano, J P, Coulange, C, Ducros, M, Rampal, M

“…Isolated human hepatocytes provide a useful model for studying xenobiotic metabolism. However, in vitro studies using human hepatocytes are scarce due to the…”
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Determination of chloroquine and monodesethylchloroquine in hair by Viala, A, Deturmeny, E, Aubert, C, Estadieu, M, Durand, A, Cano, J P, Delmont, J

“…Using thin-layer and gas chromatography and mass spectrometry, chloroquine and its major metabolite (monodesethylchloroquine) were identified in hair samples…”
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Pharmacokinetics and metabolism of Navelbine by Krikorian, A, Rahmani, R, Bromet, M, Bore, P, Cano, J P

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Metabolism of digoxin, digoxigenin digitoxosides and digoxigenin in human hepatocytes and liver microsomes by Lacarelle, B, Rahmani, R, de Sousa, G, Durand, A, Placidi, M, Cano, J P

“…In vitro metabolism of digoxin and its cleavage-related compounds was investigated using hepatocytes in primary culture and microsomal fractions both isolated…”
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Clinical pharmacokinetics of the antitumor drug navelbine (5'-noranhydrovonblastine) by RAHMANI, R, BRUNO, R, ILIADIS, A, FAVRE, R, JUST, S, BARBET, J, CANO, J.-P

“…Eleven patients with advanced cancer received navelbine (15 mg/m2) as a single i.v. bolus injection. At least 1 week later, the patients were given a 2-fold…”
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An in vitro nucleoside analog screening method for cancer gene therapy by Evrard, A, Vian, L, Aubert, C, Cano, J P

“…Suicide genes that sensitize cells to drugs that are normally nontoxic at therapeutic levels represent an important approach in human gene therapy research. We…”
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Interspecies variability in mitoxantrone metabolism using primary cultures of hepatocytes isolated from rat, rabbit and humans by Richard, B, Fabre, G, De Sousa, G, Fabre, I, Rahmani, R, Cano, J P

“…Metabolism of mitoxantrone was studied in primary cultures of hepatocytes freshly obtained from rat, rabbit and humans. Metabolic pattern was evaluated by a…”
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Pharmacokinetics of a new anticancer drug, navelbine, in patients. Comparative study of radioimmunologic and radioactive determination methods by BORE, P, RAHMANI, R, VAN CANTFORT, J, FOCAN, C, CANO, J. P

“…A study was designed to investigate the fate of navelbine (NVB) and its excretion routes in two cancer patients treated with tritiated NVB (30 mg/m2) by i.v…”
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