Search Results - "Cannon, Robert C"
-
1
Stochastic ion channel gating in dendritic neurons: morphology dependence and probabilistic synaptic activation of dendritic spikes
Published in PLoS computational biology (01-08-2010)“…Neuronal activity is mediated through changes in the probability of stochastic transitions between open and closed states of ion channels. While differences in…”
Get full text
Journal Article -
2
NeuroML: a language for describing data driven models of neurons and networks with a high degree of biological detail
Published in PLoS computational biology (01-06-2010)“…Biologically detailed single neuron and network models are important for understanding how ion channels, synapses and anatomical connectivity underlie the…”
Get full text
Journal Article -
3
LEMS: a language for expressing complex biological models in concise and hierarchical form and its use in underpinning NeuroML 2
Published in Frontiers in neuroinformatics (25-09-2014)“…Computational models are increasingly important for studying complex neurophysiological systems. As scientific tools, it is essential that such models can be…”
Get full text
Journal Article -
4
The ion channel inverse problem: neuroinformatics meets biophysics
Published in PLoS computational biology (01-08-2006)“…Ion channels are the building blocks of the information processing capability of neurons: any realistic computational model of a neuron must include reliable…”
Get full text
Journal Article -
5
The role of type 4 phosphodiesterases in generating microdomains of cAMP: large scale stochastic simulations
Published in PloS one (22-07-2010)“…Cyclic AMP (cAMP) and its main effector Protein Kinase A (PKA) are critical for several aspects of neuronal function including synaptic plasticity. Specificity…”
Get full text
Journal Article -
6
Modeling goal-directed spatial navigation in the rat based on physiological data from the hippocampal formation
Published in Neural networks (01-06-2003)“…We investigated the importance of hippocampal theta oscillations and the significance of phase differences of theta modulation in the cortical regions that are…”
Get full text
Journal Article Conference Proceeding -
7
Open Source Brain: A Collaborative Resource for Visualizing, Analyzing, Simulating, and Developing Standardized Models of Neurons and Circuits
Published in Neuron (Cambridge, Mass.) (07-08-2019)“…Computational models are powerful tools for exploring the properties of complex biological systems. In neuroscience, data-driven models of neural circuits that…”
Get full text
Journal Article -
8
Open source software development for neuroinformatics
Published in Frontiers in neuroinformatics (03-04-2008)“…A commentary on Concierge: Personal database software for managing digital research resources by Hiroyuki Sakai, Toshihiro Aoyama, Kazutsuna Yamaji and Shiro…”
Get full text
Journal Article -
9
libNeuroML and PyLEMS: using Python to combine procedural and declarative modeling approaches in computational neuroscience
Published in Frontiers in neuroinformatics (23-04-2014)“…NeuroML is an XML-based model description language, which provides a powerful common data format for defining and exchanging models of neurons and neuronal…”
Get full text
Journal Article -
10
Interoperability of neuroscience modeling software: current status and future directions
Published in Neuroinformatics (Totowa, N.J.) (01-04-2007)“…Neuroscience increasingly uses computational models to assist in the exploration and interpretation of complex phenomena. As a result, considerable effort is…”
Get full text
Journal Article -
11
The evolution and final fate of massive Thorne-Żytkow objects
Published in Monthly notices of the Royal Astronomical Society (15-05-1995)“…Massive Thorne-Żytkow objects (TŻOs) are red supergiants with neutron cores which are expected to form as a result of unstable mass transfer in massive X-ray…”
Get full text
Journal Article -
12
From biophysics to behavior: Catacomb2 and the design of biologically-plausible models for spatial navigation
Published in Neuroinformatics (Totowa, N.J.) (2003)“…A variety of approaches are available for using computational models to help understand neural processes over many levels of description, from sub-cellular…”
Get full text
Journal Article -
13
Pro-epileptic changes in synaptic function can be accompanied by pro-epileptic changes in neuronal excitability
Published in Trends in neurosciences (Regular ed.) (01-04-1998)“…Repetitive sensory input, stroboscopic lights or repeated sounds can induce epileptic seizures in susceptible individuals. In order to understand the process…”
Get full text
Journal Article -
14
A small contribution to the giant problem
Published in Monthly notices of the Royal Astronomical Society (11-08-1998)“…We present a simple analytic model of a composite polytropic star, which exhibits a limiting Schönberg—Chandrasekhar core mass fraction strongly analogous to…”
Get full text
Journal Article -
15
Axiope tools for data management and data sharing
Published in Neuroinformatics (Totowa, N.J.) (2003)“…Many areas of biological research generate large volumes of very diverse data. Managing this data can be a difficult and time-consuming process, particularly…”
Get full text
Journal Article -
16
The NeuroML ecosystem for standardized multi-scale modeling in neuroscience
Published in eLife (03-05-2024)“…Data-driven models of neurons and circuits are important for understanding how the properties of membrane conductances, synapses, dendrites and the anatomical…”
Get full text
Journal Article -
17
Stochastic Ion Channel Gating in Dendritic Neurons: Morphology Dependence and Probabilistic Synaptic Activation of Dendritic Spikes: e1000886
Published in PLoS computational biology (01-08-2010)“…Neuronal activity is mediated through changes in the probability of stochastic transitions between open and closed states of ion channels. While differences in…”
Get full text
Journal Article -
18
NeuroML: A Language for Describing Data Driven Models of Neurons and Networks with a High Degree of Biological Detail: e1000815
Published in PLoS computational biology (01-06-2010)“…Biologically detailed single neuron and network models are important for understanding how ion channels, synapses and anatomical connectivity underlie the…”
Get full text
Journal Article -
19
libNeuroML and PyLEMS: using Python to combine imperative and declarative modelling approaches in computational neuroscience
Published in Frontiers in neuroinformatics (01-04-2014)“…NeuroML is an XML-based model description language, which provides a powerful common data format for defining and exchanging models of neurons and neuronal…”
Get full text
Journal Article -
20
Reaction Rate Uncertainties and the Production of 19F in Asymptotic Giant Branch Stars
Published in The Astrophysical journal (10-11-2004)Get full text
Journal Article