Search Results - "Canning, J"

Fibre gratings and devices for sensors and lasers by Canning, J.

“…Although mainstream grating writing, more often than not using single photon excitation of germanosilicate based defects with CW 244 nm light, remains the key…”
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Reflex regulation of airway smooth muscle tone by Canning, Brendan J

“…Johns Hopkins Asthma and Allergy Center, Baltimore, Maryland Autonomic nerves in most mammalian species mediate both contractions and relaxations of airway…”
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EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction by Zhao, Jing, Blayney, Alan, Liu, Xiaorong, Gandy, Lauren, Jin, Weihua, Yan, Lufeng, Ha, Jeung-Hoi, Canning, Ashley J., Connelly, Michael, Yang, Chao, Liu, Xinyue, Xiao, Yuanyuan, Cosgrove, Michael S., Solmaz, Sozanne R., Zhang, Yingkai, Ban, David, Chen, Jianhan, Loh, Stewart N., Wang, Chunyu

“…Epigallocatechin gallate (EGCG) from green tea can induce apoptosis in cancerous cells, but the underlying molecular mechanisms remain poorly understood. Using…”
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ALS-Linked Mutations Affect UBQLN2 Oligomerization and Phase Separation in a Position- and Amino Acid-Dependent Manner by Dao, Thuy P., Martyniak, Brian, Canning, Ashley J., Lei, Yongna, Colicino, Erica G., Cosgrove, Michael S., Hehnly, Heidi, Castañeda, Carlos A.

“…Proteasomal shuttle factor UBQLN2 is recruited to stress granules and undergoes liquid-liquid phase separation (LLPS) into protein-containing droplets…”
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First evaluation of neustonic microplastics in the Macaronesian region, NE Atlantic by Herrera, A., Raymond, E., Martínez, I., Álvarez, S., Canning-Clode, J., Gestoso, I., Pham, C.K., Ríos, N., Rodríguez, Y., Gómez, M.

“…Marine microplastic pollution is an issue of great concern nowadays since high concentrations have been detected in the ocean, mainly in the subtropical gyres…”
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Encoding of the cough reflex in anesthetized guinea pigs by Canning, Brendan J, Mori, Nanako

“…We have previously described the physiological and morphological properties of the cough receptors and their sites of termination in the airways and centrally…”
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Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling by Hollenhorst, Monika I., Jurastow, Innokentij, Nandigama, Rajender, Appenzeller, Silke, Li, Lei, Vogel, Jörg, Wiederhold, Stephanie, Althaus, Mike, Empting, Martin, Altmüller, Janine, Hirsch, Anna K. H., Flockerzi, Veit, Canning, Brendan J., Saliba, Antoine‐Emmanuel, Krasteva‐Christ, Gabriela

“…For protection from inhaled pathogens many strategies have evolved in the airways such as mucociliary clearance and cough. We have previously shown that…”
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Cholinergic chemosensory cells in the trachea regulate breathing by Krasteva, Gabriela, Canning, Brendan J., Hartmann, Petra, Veres, Tibor Z., Papadakis, Tamara, Mühlfeld, Christian, Schliecker, Kirstin, Tallini, Yvonne N., Braun, Armin, Hackstein, Holger, Baal, Nelli, Weihe, Eberhard, Schütz, Burkhard, Kotlikoff, Michael, Ibanez-Tallon, Ines, Kummer, Wolfgang

“…In the epithelium of the lower airways, a cell type of unknown function has been termed "brush cell" because of a distinctive ultrastructural feature, an…”
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Parallel functional annotation of cancer-associated missense mutations in histone methyltransferases by Canning, Ashley J., Viggiano, Susan, Fernandez-Zapico, Martin E., Cosgrove, Michael S.

“…Using exome sequencing for biomarker discovery and precision medicine requires connecting nucleotide-level variation with functional changes in encoded…”
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Evidence for autocrine and paracrine regulation of allergen-induced mast cell mediator release in the guinea pig airways by Yu, Li, Liu, Qi, Canning, Brendan J.

“…Mast cells play an essential role in immediate type hypersensitivity reactions and in chronic allergic diseases of the airways, including asthma. Mast cell…”
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Morphologic Characterization of Nerves in Whole-Mount Airway Biopsies by West, Peter W, Canning, Brendan J, Merlo-Pich, Emilio, Woodcock, Ashley A, Smith, Jaclyn A

“…Neuroplasticity of bronchopulmonary afferent neurons that respond to mechanical and chemical stimuli may sensitize the cough reflex. Afferent drive in cough is…”
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Shigella IpaH9.8 limits GBP1-dependent LPS release from intracytosolic bacteria to suppress caspase-4 activation by Goers, Lisa, Kim, Kyungsub, Stedman, Teagan C, Canning, Patrick J, Mou, Xiangyu, Ernst, Nadja Heinz, Coers, Jörn, Lesser, Cammie F

“…Pyroptosis is an inflammatory form of cell death induced upon recognition of invading microbes. During an infection, pyroptosis is enhanced in…”
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A study of regenerated gratings produced in germanosilicate fibers by high temperature annealing by Bandyopadhyay, S, Canning, J, Biswas, P, Stevenson, M, Dasgupta, K

“…In light of recent proposals linking structural change and stresses within regenerated gratings, the details of regeneration of a seed Type-I Bragg grating…”
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Central regulation of the cough reflex: Therapeutic implications by Canning, Brendan J

“…Abstract In many species including humans, antagonists of NMDA-type glutamate receptors such as dextromethorphan, when used at sufficient doses, have been…”
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Afferent Nerves Regulating the Cough Reflex: Mechanisms and Mediators of Cough in Disease by Canning, Brendan J., PhD

“…Bronchopulmonary C fibers and acid-sensitive, capsaicin-insensitive mechanoreceptors innervating the larynx, trachea, and large bronchi regulate the cough…”
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The role of trigeminal nasal TRPM8-expressing afferent neurons in the antitussive effects of menthol by Plevkova, J, Kollarik, M, Poliacek, I, Brozmanova, M, Surdenikova, L, Tatar, M, Mori, N, Canning, B J

“…The cold-sensitive cation channel TRPM8 is a target for menthol, which is used routinely as a cough suppressant and as an additive to tobacco and food…”
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Parainfluenza 3-Induced Cough Hypersensitivity in the Guinea Pig Airways by Zaccone, Eric J, Lieu, TinaMarie, Muroi, Yukiko, Potenzieri, Carl, Undem, Blair E, Gao, Peisong, Han, Liang, Canning, Brendan J, Undem, Bradley J

“…The effect of respiratory tract viral infection on evoked cough in guinea pigs was evaluated. Guinea pigs were inoculated intranasally with either…”
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Synergistic interactions between airway afferent nerve subtypes regulating the cough reflex in guinea-pigs by Mazzone, Stuart B., Mori, Nanako, Canning, Brendan J.

“…Cough initiated from the trachea and larynx in anaesthetized guinea-pigs is mediated by capsaicin-insensitive, mechanically sensitive vagal afferent neurones…”
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Nanophotonics inside structured optical fibres by Canning, J.

“…Adding functionality to structured optical fibres promises to enhance their application range. This functionality critically depends on the evanescent field…”
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Opposing effects of bronchopulmonary C-fiber subtypes on cough in guinea pigs by Chou, Yang-Ling, Mori, Nanako, Canning, Brendan J

“…We have addressed the hypothesis that the opposing effects of bronchopulmonary C-fiber activation on cough are attributable to the activation of C-fiber…”
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