Search Results - "Canniff, John"
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Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma
Published in Cell reports (Cambridge) (25-06-2024)“…Renal cell carcinoma with sarcomatoid differentiation (sRCC) is associated with poor survival and a heightened response to immune checkpoint inhibitors (ICIs)…”
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Detection of neuroendocrine prostate cancer through plasma-based epigenomic profiling
Published in Journal of clinical oncology (01-02-2024)“…201 Background: Neuroendocrine prostate cancer (NEPC) is an aggressive resistance phenotype that can develop in men with metastatic prostate adenocarcinoma…”
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43 Epigenomic profiling of translocation renal cell carcinoma via liquid biopsy
Published in The oncologist (Dayton, Ohio) (06-08-2024)“…Abstract Background Translocation renal cell carcinoma (tRCC) is an aggressive subtype of kidney cancer usually driven by a fusion involving the TFE3 gene. Due…”
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Liquid biopsy epigenomic profiling for cancer subtyping
Published in Nature medicine (01-11-2023)“…Although circulating tumor DNA (ctDNA) assays are increasingly used to inform clinical decisions in cancer care, they have limited ability to identify the…”
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Detection of sarcomatoid renal cell carcinoma using plasma cell-free DNA methylation
Published in Journal of clinical oncology (01-02-2024)“…449 Background: Sarcomatoid differentiation (SD) in renal cell carcinoma (RCC) is associated with poor survival and heightened response to immune checkpoint…”
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46 Radiological tumor burden is an independent risk factor for survival in patients with metastatic clear cell renal cell carcinoma (mccRCC) treated with first line immunotherapy (IO)-based regimens
Published in The oncologist (Dayton, Ohio) (06-08-2024)“…Abstract Background IO-based regimens (IO + IO or IO + VEGF inhibitor) represent current standard of care systemic therapies for the management of patients…”
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44 Liquid biopsy epigenomic profiling for the detection of sarcomatoid renal cell carcinoma
Published in The oncologist (Dayton, Ohio) (06-08-2024)“…Abstract Background Sarcomatoid differentiation (SD) in renal cell carcinoma (RCC) is associated with poor survival and heightened response to immune…”
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Detecting small cell transformation in patients with advanced EGFR mutant lung adenocarcinoma through epigenomic cfDNA profiling
Published in Clinical cancer research (03-09-2024)“…Histologic transformation to small cell lung cancer (SCLC) is a mechanism of treatment resistance in patients with advanced oncogene-driven lung adenocarcinoma…”
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Author Correction: Liquid biopsy epigenomic profiling for cancer subtyping
Published in Nature medicine (01-03-2024)Get full text
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Abstract PS06-07: Liquid biopsy determination of HER2 status in breast cancer: results from a novel epigenomic platform
Published in Cancer research (Chicago, Ill.) (02-05-2024)“…Abstract Background: Tumor HER2 status remains a critical predictive biomarker for patients with breast cancer given the availability of highly effective…”
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