Search Results - "Cannella, Lee Anne"
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Acute administration of catalase targeted to ICAM-1 attenuates neuropathology in experimental traumatic brain injury
Published in Scientific reports (19-06-2017)“…Traumatic brain injury (TBI) contributes to one third of injury related deaths in the US. Treatment strategies for TBI are supportive, and the pathophysiology…”
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2
Endothelial progenitor cells in ischemic stroke: an exploration from hypothesis to therapy
Published in Journal of hematology and oncology (11-04-2015)“…As the population ages and lifestyles change in concordance, the number of patients suffering from ischemic stroke and its associated disabilities is…”
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3
Dexamethasone Attenuates the Enhanced Rewarding Effects of Cocaine Following Experimental Traumatic Brain Injury
Published in Cell transplantation (01-07-2017)“…Clinical studies have identified traumatic brain injury (TBI) as a risk factor for the development of cocaine dependence. This claim is supported by our recent…”
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4
Brain interrupted: Early life traumatic brain injury and addiction vulnerability
Published in Experimental neurology (01-07-2019)“…Recent reports provide evidence for increased risk of substance use disorders (SUD) among patients with a history of early-life traumatic brain injury (TBI)…”
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Factors affecting increased risk for substance use disorders following traumatic brain injury: What we can learn from animal models
Published in Neuroscience and biobehavioral reviews (01-06-2017)“…Effects of traumatic brain injury (TBI) on mechanisms implicated in substance use disorders (SUDs). Recent studies find that TBI may affect many key brain…”
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Experimental Traumatic Brain Injury during Adolescence Enhances Cocaine Rewarding Efficacy and Dysregulates Dopamine and Neuroimmune Systems in Brain Reward Substrates
Published in Journal of neurotrauma (01-01-2020)“…Although clinical studies identify traumatic brain injury (TBI) as a risk factor for the development of substance use disorder, much remains unknown about the…”
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7
Reward and immune responses in adolescent females following experimental traumatic brain injury
Published in Behavioural brain research (03-02-2020)“…•Cocaine sensitivity increases after traumatic brain injury (TBI) in male mice.•High levels of female hormones protect against cocaine sensitivity after…”
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8
Glutamate carboxypeptidase II
Published in Psychopharmacology (01-06-2017)“…Rationale Metabotropic glutamate 2 and 3 (mGluR2/3) receptors are implicated in drug addiction as they limit excessive glutamate release during relapse…”
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Adolescent Traumatic Brain Injury Induces Chronic Mesolimbic Neuroinflammation with Concurrent Enhancement in the Rewarding Effects of Cocaine in Mice during Adulthood
Published in Journal of neurotrauma (01-01-2017)“…Clinical psychiatric disorders of depression, anxiety, and substance abuse are most prevalent after traumatic brain injury (TBI). Pre-clinical research has…”
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10
Moderate TBI increases susceptibility to rewarding effects of a subthreshold dose of cocaine in mice
Published in Drug and alcohol dependence (01-02-2017)Get full text
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11
Glutamate carboxypeptidase II (GCPII) inhibitor 2-PMPA reduces rewarding effects of the synthetic cathinone MDPV in rats: a role for N-acetylaspartylglutamate (NAAG)
Published in Psychopharmacology (01-06-2017)“…Rationale Metabotropic glutamate 2 and 3 (mGluR2/3) receptors are implicated in drug addiction as they limit excessive glutamate release during relapse. N…”
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The influence of sleep on emotional and cognitive processing is primarily trait- (but not state-) dependent
Published in Neurobiology of learning and memory (01-10-2016)“…•The effects of sleep on cognition are mostly between- and not within-subject.•REM and SWS differentially affect aspects of emotional reactivity.•SWS and N1/N2…”
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13
Characterization of the Role and Underlying Mechanisms of Traumatic Brain Injury on Reward Seeking Behavior Using Preclinical Animal Models
Published 01-01-2019“…Traumatic brain injury (TBI) is a prominent healthcare concern in the U.S. as millions of TBI-related emergency department visits occur annually. Recent…”
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Dissertation