Search Results - "Canman, Julie C."

A bidirectional relationship between sleep and oxidative stress in Drosophila by Hill, Vanessa M, O'Connor, Reed M, Sissoko, Gunter B, Irobunda, Ifeoma S, Leong, Stephen, Canman, Julie C, Stavropoulos, Nicholas, Shirasu-Hiza, Mimi

“…Although sleep appears to be broadly conserved in animals, the physiological functions of sleep remain unclear. In this study, we sought to identify a…”
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Circadian autophagy drives iTRF-mediated longevity by Ulgherait, Matt, Midoun, Adil M., Park, Scarlet J., Gatto, Jared A., Tener, Samantha J., Siewert, Julia, Klickstein, Naomi, Canman, Julie C., Ja, William W., Shirasu-Hiza, Mimi

“…Time-restricted feeding (TRF) has recently gained interest as a potential anti-ageing treatment for organisms from  Drosophila  to humans 1 – 5 . TRF restricts…”
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Chromosome segregation occurs by microtubule pushing in oocytes by Laband, Kimberley, Le Borgne, Rémi, Edwards, Frances, Stefanutti, Marine, Canman, Julie C., Verbavatz, Jean-Marc, Dumont, Julien

“…During cell division, spindle microtubules ensure an equal repartition of chromosomes between the two daughter cells. While the kinetochore-dependent…”
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Circadian regulation of mitochondrial uncoupling and lifespan by Ulgherait, Matt, Chen, Anna, McAllister, Sophie F., Kim, Han X., Delventhal, Rebecca, Wayne, Charlotte R., Garcia, Christian J., Recinos, Yocelyn, Oliva, Miles, Canman, Julie C., Picard, Martin, Owusu-Ansah, Edward, Shirasu-Hiza, Mimi

“…Because old age is associated with defects in circadian rhythm, loss of circadian regulation is thought to be pathogenic and contribute to mortality. We show…”
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Maternal inheritance of functional centrioles in two parthenogenetic nematodes by Perrier, Aurélien, Guiglielmoni, Nadège, Naquin, Delphine, Gorrichon, Kevin, Thermes, Claude, Lameiras, Sonia, Dammermann, Alexander, Schiffer, Philipp H., Brunstein, Maia, Canman, Julie C., Dumont, Julien

“…Centrioles are the core constituent of centrosomes, microtubule-organizing centers involved in directing mitotic spindle assembly and chromosome segregation in…”
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Kinetochore component function in C. elegans oocytes revealed by 4D tracking of holocentric chromosomes by Pitayu-Nugroho, Laras, Aubry, Mélanie, Laband, Kimberley, Geoffroy, Hélène, Ganeswaran, Thadshagine, Primadhanty, Audi, Canman, Julie C., Dumont, Julien

“…During cell division, chromosome congression to the spindle center, their orientation along the spindle long axis and alignment at the metaphase plate depend…”
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Rho GTPases in animal cell cytokinesis: An occupation by the one percent by Jordan, Shawn N., Canman, Julie C.

“…Rho GTPases are molecular switches that elicit distinct effects on the actomyosin cytoskeleton to accurately promote cytokinesis. Although they represent less…”
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High-Resolution Temporal Analysis Reveals a Functional Timeline for the Molecular Regulation of Cytokinesis by Davies, Tim, Jordan, Shawn N., Chand, Vandana, Sees, Jennifer A., Laband, Kimberley, Carvalho, Ana X., Shirasu-Hiza, Mimi, Kovar, David R., Dumont, Julien, Canman, Julie C.

“…To take full advantage of fast-acting temperature-sensitive mutations, thermal control must be extremely rapid. We developed the Therminator, a device capable…”
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Polyploid Superficial Cells that Maintain the Urothelial Barrier Are Produced via Incomplete Cytokinesis and Endoreplication by Wang, Jia, Batourina, Ekatherina, Schneider, Kerry, Souza, Spenser, Swayne, Theresa, Liu, Chang, George, Christopher D., Tate, Tiffany, Dan, Hanbin, Wiessner, Gregory, Zhuravlev, Yelena, Canman, Julie C., Mysorekar, Indira U., Mendelsohn, Cathy Lee

“…The urothelium is an epithelia barrier lined by a luminal layer of binucleated, octoploid, superficial cells. Superficial cells are critical for production and…”
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Inhibition of Rac by the GAP Activity of Centralspindlin Is Essential for Cytokinesis by Canman, Julie C, Lewellyn, Lindsay, Laband, Kimberley, Smerdon, Stephen J, Desai, Arshad, Bowerman, Bruce, Oegema, Karen

“…During cytokinesis, the guanosine triphosphatase (GTPase) RhoA orchestrates contractile ring assembly and constriction. RhoA signaling is controlled by the…”
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FLIRT: fast local infrared thermogenetics for subcellular control of protein function by Hirsch, Sophia M., Sundaramoorthy, Sriramkumar, Davies, Tim, Zhuravlev, Yelena, Waters, Jennifer C., Shirasu-Hiza, Mimi, Dumont, Julien, Canman, Julie C.

“…FLIRT (fast local infrared thermogenetics) is a microscopy-based technology to locally and reversibly manipulate protein function while simultaneously…”
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Dissection of central clock function in Drosophila through cell-specific CRISPR-mediated clock gene disruption by Delventhal, Rebecca, O'Connor, Reed M, Pantalia, Meghan M, Ulgherait, Matthew, Kim, Han X, Basturk, Maylis K, Canman, Julie C, Shirasu-Hiza, Mimi

“…In , ~150 neurons expressing molecular clock proteins regulate circadian behavior. Sixteen of these neurons secrete the neuropeptide Pdf and have been called…”
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Drosophila mutants lacking the glial neurotransmitter-modifying enzyme Ebony exhibit low neurotransmitter levels and altered behavior by Pantalia, Meghan, Lin, Zhi, Tener, Samantha J., Qiao, Bing, Tang, Grace, Ulgherait, Matthew, O’Connor, Reed, Delventhal, Rebecca, Volpi, Julia, Syed, Sheyum, Itzhak, Nissim, Canman, Julie C., Fernández, María Paz, Shirasu-Hiza, Mimi

“…Inhibitors of enzymes that inactivate amine neurotransmitters (dopamine, serotonin), such as catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO),…”
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Synergistic stabilization of microtubules by BUB-1, HCP-1, and CLS-2 controls microtubule pausing and meiotic spindle assembly by Macaisne, Nicolas, Bellutti, Laura, Laband, Kimberley, Edwards, Frances, Pitayu-Nugroho, Laras, Gervais, Alison, Ganeswaran, Thadshagine, Geoffroy, Hélène, Maton, Gilliane, Canman, Julie C, Lacroix, Benjamin, Dumont, Julien

“…During cell division, chromosome segregation is orchestrated by a microtubule-based spindle. Interaction between spindle microtubules and kinetochores is…”
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Neuronal knockdown of Cullin3 as a Drosophila model of autism spectrum disorder by Tener, Samantha J., Lin, Zhi, Park, Scarlet J., Oraedu, Kairaluchi, Ulgherait, Matthew, Van Beek, Emily, Martínez-Muñiz, Andrés, Pantalia, Meghan, Gatto, Jared A., Volpi, Julia, Stavropoulos, Nicholas, Ja, William W., Canman, Julie C., Shirasu-Hiza, Mimi

“…Mutations in Cullin-3 ( Cul3 ), a conserved gene encoding a ubiquitin ligase, are strongly associated with autism spectrum disorder (ASD). Here, we…”
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Kinetochore components are required for central spindle assembly by Maton, Gilliane, Edwards, Frances, Lacroix, Benjamin, Stefanutti, Marine, Laband, Kimberley, Lieury, Tiffany, Kim, Taekyung, Espeut, Julien, Canman, Julie C., Dumont, Julien

“…Using C. elegans zygotes, Dumont and colleagues find that kinetochore proteins, including KNL-1, participate in assembly of central spindle microtubules for…”
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BUB-1 promotes amphitelic chromosome biorientation via multiple activities at the kinetochore by Edwards, Frances, Maton, Gilliane, Gareil, Nelly, Canman, Julie C, Dumont, Julien

“…Accurate chromosome segregation relies on bioriented amphitelic attachments of chromosomes to microtubules of the mitotic spindle, in which sister chromatids…”
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Cell-intrinsic and -extrinsic mechanisms promote cell-type-specific cytokinetic diversity by Davies, Tim, Kim, Han X, Romano Spica, Natalia, Lesea-Pringle, Benjamin J, Dumont, Julien, Shirasu-Hiza, Mimi, Canman, Julie C

“…Cytokinesis, the physical division of one cell into two, is powered by constriction of an actomyosin contractile ring. It has long been assumed that all animal…”
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The Mad1/Mad2 Complex as a Template for Mad2 Activation in the Spindle Assembly Checkpoint by De Antoni, Anna, Pearson, Chad G., Cimini, Daniela, Canman, Julie C., Sala, Valeria, Nezi, Luigi, Mapelli, Marina, Sironi, Lucia, Faretta, Mario, Salmon, Edward D., Musacchio, Andrea

“…Background: The spindle assembly checkpoint (SAC) imparts fidelity to chromosome segregation by delaying anaphase until all sister chromatid pairs have become…”
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Stuck in the middle: Rac, adhesion, and cytokinesis by Davies, Tim, Canman, Julie C

“…Rho family small GTPases (Rac, RhoA, and Cdc42) function at the core of cytokinesis, the physical division of one cell into two. In this issue, Bastos et al…”
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