Search Results - "Cani, Patrice D."
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Human gut microbiome: hopes, threats and promises
Published in Gut (01-09-2018)“…The microbiome has received increasing attention over the last 15 years. Although gut microbes have been explored for several decades, investigations of the…”
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Mucus barrier, mucins and gut microbiota: the expected slimy partners?
Published in Gut (01-12-2020)“…The gastrointestinal tract is often considered as a key organ involved in the digestion of food and providing nutrients to the body for proper maintenance…”
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Microbiota and metabolites in metabolic diseases
Published in Nature reviews. Endocrinology (01-02-2019)“…In 2018, more than 4,000 publications were dedicated to the study of the gut microbiota, and an important proportion investigated cardiometabolic disorders…”
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The gut microbiota in obesity and weight management: microbes as friends or foe?
Published in Nature reviews. Endocrinology (01-05-2023)“…Obesity is caused by a long-term difference between energy intake and expenditure — an imbalance that is seemingly easily restored by increasing exercise and…”
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Gut microbiota — at the intersection of everything?
Published in Nature reviews. Gastroenterology & hepatology (01-06-2017)“…Over the past decade, numerous studies have found an association between the gut microbiota composition and many diseases. However, is it reality? Or is the…”
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The gut microbiome influences host endocrine functions
Published in Endocrine reviews (01-10-2019)“…The gut microbiome is considered an organ contributing to the regulation of host metabolism. Since the relationship between the gut microbiome and specific…”
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Gut microbiome and health: mechanistic insights
Published in Gut (01-05-2022)“…The gut microbiota is now considered as one of the key elements contributing to the regulation of host health. Virtually all our body sites are colonised by…”
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Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling
Published in Cell metabolism (06-10-2015)“…Dietary lipids may influence the abundance of circulating inflammatory microbial factors. Hence, inflammation in white adipose tissue (WAT) induced by dietary…”
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Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila
Published in Frontiers in microbiology (22-09-2017)“…Metabolic disorders associated with obesity and cardiometabolic disorders are worldwide epidemic. Among the different environmental factors, the gut microbiota…”
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Gut Microbes and Health: A Focus on the Mechanisms Linking Microbes, Obesity, and Related Disorders
Published in Obesity (Silver Spring, Md.) (01-05-2018)“…The past decade has been characterized by tremendous progress in the field of the gut microbiota and its impact on host metabolism. Although numerous studies…”
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Diabetes, obesity and gut microbiota
Published in Baillière's best practice & research. Clinical gastroenterology (01-02-2013)“…Abstract The gut microbiota composition has been associated with several hallmarks of metabolic syndrome (e.g., obesity, type 2 diabetes, cardiovascular…”
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How gut microbes talk to organs: The role of endocrine and nervous routes
Published in Molecular metabolism (Germany) (01-09-2016)“…Abstract Background Changes in gut microbiota composition and activity have been associated with different metabolic disorders, including obesity, diabetes,…”
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Towards a more comprehensive concept for prebiotics
Published in Nature reviews. Gastroenterology & hepatology (01-05-2015)“…As understanding of the gut microbiota advances, the focus has shifted to ways to modulate the microbiota to improve health. One such strategy is the use of…”
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Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics
Published in Nature reviews. Gastroenterology & hepatology (01-08-2017)“…With the continued interest in the role of the gut microbiota in health, attention has now turned to how to harness the microbiota for the benefit of the host…”
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Targeting the Enteric Nervous System to Treat Metabolic Disorders? "Enterosynes" as Therapeutic Gut Factors
Published in Neuroendocrinology (2020)“…The gut-brain axis is of crucial importance for controlling glucose homeostasis. Alteration of this axis promotes the type 2 diabetes (T2D) phenotype…”
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How Probiotics Affect the Microbiota
Published in Frontiers in cellular and infection microbiology (15-01-2020)“…Probiotics have been used to treat a variety of diseases for decades; however, what is the rationale for their application? Such a treatment was first proposed…”
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Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
Published in Proceedings of the National Academy of Sciences - PNAS (28-05-2013)“…Obesity and type 2 diabetes are characterized by altered gut microbiota, inflammation, and gut barrier disruption. Microbial composition and the mechanisms of…”
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Gut microorganisms as promising targets for the management of type 2 diabetes
Published in Diabetologia (01-10-2015)“…Each human intestine harbours not only hundreds of trillions of bacteria but also bacteriophage particles, viruses, fungi and archaea, which constitute a…”
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Diet and depression: exploring the biological mechanisms of action
Published in Molecular psychiatry (01-01-2021)“…The field of nutritional psychiatry has generated observational and efficacy data supporting a role for healthy dietary patterns in depression onset and…”
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Microbial regulation of organismal energy homeostasis
Published in Nature metabolism (01-01-2019)“…The gut microbiome has emerged as a key regulator of host metabolism. Here we review the various mechanisms through which the gut microbiome influences the…”
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