Search Results - "Canestrari, E"

KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer by Loupakis, F, Ruzzo, A, Cremolini, C, Vincenzi, B, Salvatore, L, Santini, D, Masi, G, Stasi, I, Canestrari, E, Rulli, E, Floriani, I, Bencardino, K, Galluccio, N, Catalano, V, Tonini, G, Magnani, M, Fontanini, G, Basolo, F, Falcone, A, Graziano, F

“…Background: KRAS codons 12 and 13 mutations predict resistance to anti-EGFR monoclonal antibodies (moAbs) in metastatic colorectal cancer. Also, BRAF V600E…”
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PHLDA1 expression is controlled by an estrogen receptor-NFκB-miR-181 regulatory loop and is essential for formation of ER+ mammospheres by Kastrati, I, Canestrari, E, Frasor, J

“…Crosstalk between estrogen receptor (ER) and the inflammatory nuclear factor κB (NFκB) pathway in ER+ breast cancers may contribute to a more aggressive…”
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Human platelet lysate as a media supplement for ex vivo expansion of immune cells by Canestrari, E, Charlebois, S, Harris, S

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Characterization of a pathogen reduced human platelet lysate by Charlebois, S, Canestrari, E, Harris, S

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Genetic modulation of the Let-7 microRNA binding to KRAS 3′-untranslated region and survival of metastatic colorectal cancer patients treated with salvage cetuximab–irinotecan by Graziano, F, Canestrari, E, Loupakis, F, Ruzzo, A, Galluccio, N, Santini, D, Rocchi, M, Vincenzi, B, Salvatore, L, Cremolini, C, Spoto, C, Catalano, V, D'Emidio, S, Giordani, P, Tonini, G, Falcone, A, Magnani, M

“…There is increasing evidence that the Let-7 microRNA (miRNA) exerts an effect as a tumor suppressor by targeting the KRAS mRNA. The Let-7 complementary site…”
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Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy by Ruzzo, A, Graziano, F, Loupakis, F, Santini, D, Catalano, V, Bisonni, R, Ficarelli, R, Fontana, A, Andreoni, F, Falcone, A, Canestrari, E, Tonini, G, Mari, D, Lippe, P, Pizzagalli, F, Schiavon, G, Alessandroni, P, Giustini, L, Maltese, P, Testa, E, Menichetti, E T, Magnani, M

“…The primary end point of the study was the analysis of associations between polymorphisms with putative influence on 5-fluorouracil/irinotecan activity and…”
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High concordance of BRAF status between primary colorectal tumours and related metastatic sites: implications for clinical practice by Santini, D., Spoto, C., Loupakis, F., Vincenzi, B., Silvestris, N., Cremolini, C., Canestrari, E., Graziano, F., Galluccio, N., Salvatore, L., Caraglia, M., Zito, F.A., Colucci, G., Falcone, A., Tonini, G., Ruzzo, A.

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Molecular predictors of efficacy to anti-EGFR agents in colorectal cancer patients by Ruzzo, Annamaria, Graziano, Francesco, Canestrari, Emanuele, Magnani, Mauro

“…Recent insights into the molecular pathogenesis of colorectal cancer (CRC) have given rise to specific target-directed therapies, including monoclonal…”
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Role of KRAS let-7 LCS6 SNP in metastatic colorectal cancer patients by Ruzzo, A., Canestrari, E., Galluccio, N., Santini, D., Vincenzi, B., Tonini, G., Magnani, M., Graziano, F.

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Interleukin 1B gene (IL-1B) and interleukin 1 receptor antagonist gene (IL-1RN) polymorphisms in Helicobacter pylori-negative gastric cancer of intestinal and diffuse histotype by Ruzzo, A., Graziano, F., Pizzagalli, F., Santini, D., Battistelli, V., Panunzi, S., Canestrari, E., Catalano, V., Humar, B., Ficarelli, R., Bearzi, I., Cascinu, S., Naldi, N., Testa, E., Magnani, M.

“…Background:: Polymorphisms in the interleukin 1β gene (IL-1B-31T/C and IL-1B-511C/T single nucleotide changes) and in the interleukin 1 receptor anatagonist…”
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Liver-only metastatic colorectal cancer patients and thymidylate synthase polymorphisms for predicting response to 5-fluorouracil-based chemotherapy by Graziano, F, Ruzzo, A, Loupakis, F, Santini, D, Catalano, V, Canestrari, E, Maltese, P, Bisonni, R, Fornaro, L, Baldi, G, Masi, G, Falcone, A, Tonini, G, Giordani, P, Alessandroni, P, Giustini, L, Vincenzi, B, Magnani, M

“…We investigated the association between thymidylate synthase ( TS ) germline polymorphisms and response to 5-fluorouracil-based chemotherapy in 80 patients…”
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Variations in the interleukin-1 receptor antagonist gene impact on survival of patients with advanced colorectal cancer by Graziano, F, Ruzzo, A, Canestrari, E, Loupakis, F, Santini, D, Rulli, E, Humar, B, Galluccio, N, Bisonni, R, Floriani, I, Maltese, P, Falcone, A, Tonini, G, Catalano, V, Fontana, A, Giustini, L, Masi, G, Vincenzi, B, Alessandroni, P, Magnani, M

“…The interleukin-1 receptor antagonist (IL-1RA) cytokine is thought to counteract tumor angiogenesis/metastasis. Two single nucleotide polymorphisms in the…”
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171 - Human platelet lysate as a media supplement for ex vivo expansion of immune cells by Canestrari, E., Charlebois, S., Harris, S.

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170 - Characterization of a pathogen reduced human platelet lysate by Charlebois, S., Canestrari, E., Harris, S.

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6115 VEGF gene polymorphisms in the prediction of benefit from first-line FOLFIRI plus bevacizumab (BV) in metastatic colorectal cancer (mCRC) patients (pts) by Loupakis, F, Ruzzo, A, Salvatore, L, Canestrari, E, Cremolini, C, Santini, D, Bencardino, K, Manzoni, M, Falcone, A, Graziano, F

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PHLDA1 expression is controlled by an estrogen receptor-NF[kappa]B-miR-181 regulatory loop and is essential for formation of ER+ mammospheres by Kastrati, I, Canestrari, E, Frasor, J

“…Crosstalk between estrogen receptor (ER) and the inflammatory nuclear factor κB (NFκB) pathway in ER+ breast cancers may contribute to a more aggressive…”
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397 AUTOLOGOUS MUSCLE DERIVED CELLS TREATMENT OF FECAL INCONTINENCE: AN ANALYSIS OF EFFICACY IN WOMEN WITH OBSTETRIC INJURY by C Knowles, E Canestrari, K Cardello, R Jankowski, M Raval

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397 AUTOLOGOUS MUSCLE DERIVED CELLS TREATMENT OF FECAL INCONTINENCE: AN ANALYSIS OF EFFICACY IN WOMEN WITH OBSTETRIC INJURY by Knowles, C, Canestrari, E, Cardello, K, Jankowski, R, Raval, M

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Pharmacogenetic Profiling and Clinical Outcome of Patients With Advanced Gastric Cancer Treated With Palliative Chemotherapy by RUZZO, Annamaria, GRAZIANO, Francesco, MARI, Davide, TESTA, Enrica, SILVA, Rosarita, VINCENZI, Bruno, GIORDANI, Paolo, CASCINU, Stefano, GIUSTINI, Lucio, TONINI, Giuseppe, MAGNANI, Mauro, KAWAKAMI, Kazuyuki, WATANABE, Go, SANTINI, Daniele, CATALANO, Vincenzo, BISONNI, Renato, CANESTRARI, Emanuele, FICARELLI, Rita, MENICHETTI, Ettore Tito

“…To investigate whether polymorphisms with putative influence on fluorouracil/cisplatin activity are associated with clinical outcomes of patients with advanced…”
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Let-7a microRNA levels in KRAS -mutated colorectal carcinomas determine survival differences in patients treated with anti-EGFR by Canestrari, E., Ruzzo, A., Vincenzi, B., Galluccio, N., Perrone, G., Andreoni, F., Lorenzini, P., Rulli, E., d'Emidio, S., Catalano, V., Loupakis, F., Bisonni, R., Floriani, I., De Nictolis, M., Santini, D., Salvatore, L., Tonini, G., Falcone, A., Magnani, M., Graziano, F.

“…Abstract only…”
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