Search Results - "Candido, E Peter M"
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Functional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteins
Published in Genome biology (12-12-2001)“…BACKGROUND: The eukaryotic ubiquitin-conjugation system sets the turnover rate of many proteins and includes activating enzymes (E1s), conjugating enzymes…”
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Microwave radiation can alter protein conformation without bulk heating
Published in FEBS letters (22-05-2003)“…Exposure to microwave radiation enhances the aggregation of bovine serum albumin in vitro in a time- and temperature-dependent manner. Microwave radiation also…”
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Structure-Function Studies on Small Heat Shock Protein Oligomeric Assembly and Interaction with Unfolded Polypeptides
Published in The Journal of biological chemistry (26-09-1997)“…The small heat shock protein (smHSP) and α-crystallin genes encode a family of 12–43-kDa proteins which assemble into large multimeric structures, function as…”
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Functional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteins
Published in Genome biology (01-01-2002)“…The eukaryotic ubiquitin-conjugation system sets the turnover rate of many proteins and includes activating enzymes (E1s), conjugating enzymes (UBCs/E2s), and…”
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Characterization of C. elegans RING finger protein 1, a binding partner of ubiquitin-conjugating enzyme 1
Published in Developmental biology (15-01-2004)“…In a yeast two-hybrid screen, RING finger protein 1 (RFP-1) and UBR1 were identified as potential binding partners of C. elegans UBC-1, a ubiquitin-conjugating…”
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HSP25, a Small Heat Shock Protein Associated with Dense Bodies and M-lines of Body Wall Muscle in Caenorhabditis elegans
Published in The Journal of biological chemistry (31-03-2000)“…HSP25, a previously uncharacterized member of the α-crystallin family of small heat shock proteins inCaenorhabditis elegans, has been examined using…”
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Unique Structural Features of a Novel Class of Small Heat Shock Proteins
Published in The Journal of biological chemistry (09-05-1997)“…Small heat shock proteins (smHSPs) and α-crystallins constitute a family of related molecular chaperones that exhibit striking variability in size, ranging…”
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Biochemical characterization of Caenorhabditis elegans UBC-1: self-association and auto-ubiquitination of a RAD6-like ubiquitin-conjugating enzyme in vitro
Published in Biochemical journal (15-10-1997)“…The Caenorhabditis elegans ubiquitin-conjugating enzyme UBC-1 is distinct from other RAD6 homologues in possessing a C-terminal tail 40 amino acid residues…”
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Construction and evaluation of a transgenic hsp16-GFP-lacZ Caenorhabditis elegans strain for environmental monitoring
Published in Environmental toxicology and chemistry (01-01-2003)“…A novel integrated transgenic Caenorhabditis elegans strain (PC161) incorporates a double reporter construct with green fluorescent protein (GFP) and lacZ…”
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Heat shock protein accumulation is upregulated in a long-lived mutant of Caenorhabditis elegans
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-07-2001)“…We present evidence for elevated levels of heat shock protein 16 (HSP16) in an intrinsically thermotolerant, long-lived strain of Caenorhabditis elegans during…”
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The NED-8 Conjugating System in Caenorhabditis elegans Is Required for Embryogenesis and Terminal Differentiation of the Hypodermis
Published in Developmental biology (01-10-2000)“…This work has identified the enzymes involved in the activation and conjugation of the ubiquitin-like protein NED-8 in Caenorhabditis elegans. A C. elegans…”
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Construction and evaluation of a transgenic hsp16-GFP-lacZ Caenorhabditis elegans strain for environmental monitoring
Published in Environmental toxicology and chemistry (01-01-2003)“…A novel integrated transgenic Caenorhabditis elegans strain (PC 161) incorporates a double reporter construct with green fluorescent protein (GFP) and lacZ…”
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Histone deacetylase from HeLa cells: properties of the high molecular weight complex
Published in Biochemistry (Easton) (01-12-1983)“…In previous work [Hay, C. W., & Candido, E. P. M. (1983) J. Biol. Chem. 258, 3726-3734], we have shown that the histone deacetylase from HeLa cell nuclei is…”
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Association of several small heat-shock proteins with reproductive tissues in the nematode Caenorhabditis elegans
Published in Biochemical journal (01-10-2000)“…Immunohistochemical data on 10 of the 14 small heat-shock (smHSPs) proteins in fourth larval stage and adult Caenorhabditis elegans show that the tissues…”
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HSP43, a small heat-shock protein localized to specific cells of the vulva and spermatheca in the nematode Caenorhabditis elegans
Published in Biochemical journal (15-07-2000)“…Heat-shock protein 43 (HSP43) of Caenorhabditis elegans is prominently expressed in the utse cell, which attaches the uterus to the hypodermis, the uv1 cells…”
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Temporal and spatial expression patterns of the small heat shock (hsp16) genes in transgenic Caenorhabditis elegans
Published in Molecular biology of the cell (01-02-1992)“…The expression of the hsp16 gene family in Caenorhabditis elegans has been examined by introducing hsp16-lacZ fusions into the nematode by transformation…”
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Targeted single-cell induction of gene products in Caenorhabditis elegans: a new tool for developmental studies
Published in The Journal of experimental zoology (01-07-1993)“…Heat shock promoters have been employed to achieve tightly regulated expression of transformed genes in a wide variety of model systems including tissue…”
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Caenorhabditis elegans small heat-shock proteins Hsp12.2 and Hsp12.3 form tetramers and have no chaperone-like activity
Published in FEBS letters (21-08-1998)“…Four 12.2–12.6 kDa small heat-shock proteins (sHSPs) of Caenorhabditis elegans are the smallest known members of the sHSP family. They essentially comprise the…”
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