Search Results - "Cancers"

Breast Cancer—Epidemiology, Risk Factors, Classification, Prognostic Markers, and Current Treatment Strategies—An Updated Review by Łukasiewicz, Sergiusz, Czeczelewski, Marcin, ma, Alicja, Baj, Jacek, Sitarz, Robert, Stanisławek, Andrzej

“…Breast cancer (BC) is the most frequently diagnosed cancer in women worldwide with more than 2 million new cases in 2020. Its incidence and death rates have…”
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Review of Indications of FDA-Approved Immune Checkpoint Inhibitors per NCCN Guidelines with the Level of Evidence by Vaddepally, Raju K, Kharel, Prakash, Pandey, Ramesh, Garje, Rohan, Chandra, Abhinav B

“…Cancer is associated with higher morbidity and mortality and is the second leading cause of death in the US. Further, in some nations, cancer has overtaken…”
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Colorectal Cancer: A Review of Carcinogenesis, Global Epidemiology, Current Challenges, Risk Factors, Preventive and Treatment Strategies by Hossain, Md Sanower, Karuniawati, Hidayah, Jairoun, Ammar Abdulrahman, Urbi, Zannat, Ooi, Der Jiun, John, Akbar, Lim, Ya Chee, Kibria, K M Kaderi, Mohiuddin, A K M, Ming, Long Chiau, Goh, Khang Wen, Hadi, Muhammad Abdul

“…Colorectal cancer (CRC) is the second most deadly cancer. Global incidence and mortality are likely to be increased in the coming decades. Although the deaths…”
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A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis by Sawicki, Tomasz, Ruszkowska, Monika, Danielewicz, Anna, Niedźwiedzka, Ewa, Arłukowicz, Tomasz, Przybyłowicz, Katarzyna E

“…This review article contains a concise consideration of genetic and environmental risk factors for colorectal cancer. Known risk factors associated with…”
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A Comprehensive Review on MAPK: A Promising Therapeutic Target in Cancer by Braicu, Cornelia, Buse, Mihail, Busuioc, Constantin, Drula, Rares, Gulei, Diana, Raduly, Lajos, Rusu, Alexandru, Irimie, Alexandru, Atanasov, Atanas G., Slaby, Ondrej, Ionescu, Calin, Berindan-Neagoe, Ioana

“…The mitogen-activated protein kinase (MAPK) pathway is an important bridge in the switch from extracellular signals to intracellular responses. Alterations of…”
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JAK-STAT Signaling: A Double-Edged Sword of Immune Regulation and Cancer Progression by Owen, Katie L, Brockwell, Natasha K, Parker, Belinda S

“…Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling mediates almost all immune regulatory processes, including those that are…”
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Recent Advances in Zinc Oxide Nanoparticles (ZnO NPs) for Cancer Diagnosis, Target Drug Delivery, and Treatment by Anjum, Sumaira, Hashim, Mariam, Malik, Sara Asad, Khan, Maha, Lorenzo, José M, Abbasi, Bilal Haider, Hano, Christophe

“…Cancer is regarded as one of the most deadly and mirthless diseases and it develops due to the uncontrolled proliferation of cells. To date, varieties of…”
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Active Targeting Strategies Using Biological Ligands for Nanoparticle Drug Delivery Systems by Yoo, Jihye, Park, Changhee, Yi, Gawon, Lee, Donghyun, Koo, Heebeom

“…Targeting nanoparticle (NP) carriers to sites of disease is critical for their successful use as drug delivery systems. Along with optimization of…”
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Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways by Wee, Ping, Wang, Zhixiang

“…The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly upregulated in cancers such as in non-small-cell lung cancer,…”
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Flavonoids in Cancer and Apoptosis by Abotaleb, Mariam, Samuel, Samson Mathews, Varghese, Elizabeth, Varghese, Sharon, Kubatka, Peter, Liskova, Alena, Büsselberg, Dietrich

“…Cancer is the second leading cause of death globally. Although, there are many different approaches to cancer treatment, they are often painful due to adverse…”
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Coumarins and Coumarin-Related Compounds in Pharmacotherapy of Cancer by Küpeli Akkol, Esra, Genç, Yasin, Karpuz, Büşra, Sobarzo-Sánchez, Eduardo, Capasso, Raffaele

“…Cancer is one of the most common causes of disease-related deaths worldwide. Despite the discovery of many chemotherapeutic drugs that inhibit uncontrolled…”
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Epidemiology of Glioblastoma Multiforme-Literature Review by Grochans, Szymon, Cybulska, Anna Maria, Simińska, Donata, Korbecki, Jan, Kojder, Klaudyna, Chlubek, Dariusz, Baranowska-Bosiacka, Irena

“…Glioblastoma multiforme (GBM) is one of the most aggressive malignancies, with a median overall survival of approximately 15 months. In this review, we analyze…”
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EGFR in Cancer: Signaling Mechanisms, Drugs, and Acquired Resistance by Uribe, Mary Luz, Marrocco, Ilaria, Yarden, Yosef

“…The epidermal growth factor receptor (EGFR) has served as the founding member of the large family of growth factor receptors harboring intrinsic tyrosine…”
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Tyrosine Kinase Inhibitors in Cancer: Breakthrough and Challenges of Targeted Therapy by Pottier, Charles, Fresnais, Margaux, Gilon, Marie, Jérusalem, Guy, Longuespée, Rémi, Sounni, Nor Eddine

“…Receptor tyrosine kinases (RTKs) are key regulatory signaling proteins governing cancer cell growth and metastasis. During the last two decades, several…”
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Organoid and Spheroid Tumor Models: Techniques and Applications by Gunti, Sreenivasulu, Hoke, Austin T K, Vu, Kenny P, London, Jr, Nyall R

“…Techniques to develop three-dimensional cell culture models are rapidly expanding to bridge the gap between conventional cell culture and animal models…”
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Obesity and Cancer: A Current Overview of Epidemiology, Pathogenesis, Outcomes, and Management by Pati, Sukanya, Irfan, Wadeed, Jameel, Ahmad, Ahmed, Shahid, Shahid, Rabia K

“…Obesity or excess body fat is a major global health challenge that has not only been associated with diabetes mellitus and cardiovascular disease but is also a…”
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CA125 and Ovarian Cancer: A Comprehensive Review by Charkhchi, Parsa, Cybulski, Cezary, Gronwald, Jacek, Wong, Fabian Oliver, Narod, Steven A, Akbari, Mohammad R

“…Ovarian cancer is the second most lethal gynecological malignancy. The tumour biomarker CA125 has been used as the primary ovarian cancer marker for the past…”
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Vimentin Is at the Heart of Epithelial Mesenchymal Transition (EMT) Mediated Metastasis by Usman, Saima, Waseem, Naushin H., Nguyen, Thuan Khanh Ngoc, Mohsin, Sahar, Jamal, Ahmad, Teh, Muy-Teck, Waseem, Ahmad

“…Epithelial-mesenchymal transition (EMT) is a reversible plethora of molecular events where epithelial cells gain the phenotype of mesenchymal cells to invade…”
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Gut Microbiota and Cancer: From Pathogenesis to Therapy by Vivarelli, Silvia, Salemi, Rossella, Candido, Saverio, Falzone, Luca, Santagati, Maria, Stefani, Stefania, Torino, Francesco, Banna, Giuseppe Luigi, Tonini, Giuseppe, Libra, Massimo

“…Cancer is a multifactorial pathology and it represents the second leading cause of death worldwide. In the recent years, numerous studies highlighted the dual…”
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The Landscape of Targeted Therapies in TNBC by Vagia, Elena, Mahalingam, Devalingam, Cristofanilli, Massimo

“…Triple negative breast cancer (TNBC) constitutes the most aggressive molecular subtype among breast tumors. Despite progress on the underlying tumor biology,…”
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