Search Results - "Cancer prevention research (Philadelphia, Pa.)"

Disparities in Cancer Prevention in the COVID-19 Era by Carethers, John M, Sengupta, Rajarshi, Blakey, Rea, Ribas, Antoni, D'Souza, Gypsyamber

“…Screening for cancer is a proven and recommended approach to prevent deaths from cancer; screening can locate precursor lesions and/or cancer at early stages…”
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Effects of Switching to Electronic Cigarettes with and without Concurrent Smoking on Exposure to Nicotine, Carbon Monoxide, and Acrolein by McRobbie, Hayden, Phillips, Anna, Goniewicz, Maciej L, Smith, Katie Myers, Knight-West, Oliver, Przulj, Dunja, Hajek, Peter

“…Concern has been raised about the presence of toxicants in electronic cigarette (EC) aerosol, particularly carbonyl compounds (e.g., acrolein) that can be…”
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Tobacco Treatment Program Implementation at NCI Cancer Centers: Progress of the NCI Cancer Moonshot-Funded Cancer Center Cessation Initiative by D'Angelo, Heather, Rolland, Betsy, Adsit, Robert, Baker, Timothy B, Rosenblum, Marika, Pauk, Danielle, Morgan, Glen D, Fiore, Michael C

“…Quitting smoking leads to improved outcomes for patients with cancer, yet too few patients receive cessation services during their oncology healthcare visits…”
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Comparison of Systemic Exposure to Toxic and/or Carcinogenic Volatile Organic Compounds (VOC) during Vaping, Smoking, and Abstention by St Helen, Gideon, Liakoni, Evangelia, Nardone, Natalie, Addo, Newton, Jacob, 3rd, Peyton, Benowitz, Neal L

“…Comparisons of systemic exposure to toxicants during monitored cigarette smoking, electronic cigarette (e-cigarette) use, and abstention are needed to enhance…”
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DNA Hypomethylation Contributes to Genomic Instability and Intestinal Cancer Initiation by Sheaffer, Karyn L, Elliott, Ellen N, Kaestner, Klaus H

“…Intestinal cancer is a heterogeneous disease driven by genetic mutations and epigenetic changes. Approximately 80% of sporadic colorectal cancers are initiated…”
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A Phase I Trial of Berberine in Chinese with Ulcerative Colitis by Xu, Li, Zhang, Yujie, Xue, Xianmin, Liu, Jie, Li, Zeng-Shan, Yang, Guang-Yu, Song, Ying, Pan, Yan, Ma, Yueyun, Hu, Sijun, Wen, Aidong, Jia, Yanyan, Rodriguez, Luz Maria, Tull, Mary Beth, Benante, Kelly, Khan, Seema A, Cao, Ying, Jovanovic, Borko, Richmond, Ellen, Umar, Asad, Bergan, Raymond, Wu, Kaichun

“…The Chinese natural product, berberine, has biological properties that support its potential efficacy as a colon cancer prevention agent. Its longstanding use…”
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Adherence to endocrine therapy in breast cancer adjuvant and prevention settings by Chlebowski, Rowan T, Kim, Jisang, Haque, Reina

“…Adherence to oral endocrine therapy in adjuvant breast cancer settings is a substantial clinical problem. To provide current perspective on adherence to oral…”
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Dietary Tomato Powder Inhibits High-Fat Diet-Promoted Hepatocellular Carcinoma with Alteration of Gut Microbiota in Mice Lacking Carotenoid Cleavage Enzymes by Xia, Hui, Liu, Chun, Li, Cheng-Chung, Fu, Maobin, Takahashi, Shingo, Hu, Kang-Quan, Aizawa, Koichi, Hiroyuki, Suganuma, Wu, Guojun, Zhao, Liping, Wang, Xiang-Dong

“…Both incidence and death rate due to liver cancer have increased in the United States. Higher consumption of lycopene-rich tomato and tomato products is…”
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Clonal Evolution in Healthy and Premalignant Tissues: Implications for Early Cancer Interception Strategies by Rane, Jayant K, Frankell, Alexander M, Weeden, Clare E, Swanton, Charles

“…Histologically normal human tissues accumulate significant mutational burden with age. The extent and spectra of mutagenesis are comparable both in rapidly…”
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Targeting Inflammation in Cancer Prevention and Therapy by Todoric, Jelena, Antonucci, Laura, Karin, Michael

“…Inflammation is associated with the development and malignant progression of most cancers. As most of the cell types involved in cancer-associated inflammation…”
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Protein Advanced Glycation End Products and Their Implications in Pancreatic Cancer by Senavirathna, Lakmini, Pan, Sheng, Chen, Ru

“…Protein advanced glycation end products (AGE) formed by nonenzymatic glycation can disrupt the normal structure and function of proteins, and stimulate the…”
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Reversing the Genomic, Epigenetic, and Triple-Negative Breast Cancer-Enhancing Effects of Obesity by Bowers, Laura W, Doerstling, Steven S, Shamsunder, Meghana G, Lineberger, Claire G, Rossi, Emily L, Montgomery, Stephanie A, Coleman, Michael F, Gong, Weida, Parker, Joel S, Howell, Anthony, Harvie, Michelle, Hursting, Stephen D

“…The reversibility of the procancer effects of obesity was interrogated in formerly obese C57BL/6 mice that lost weight via a nonrestricted low-fat diet (LFD)…”
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Germline Testing Identifies Pathogenic/Likely Pathogenic Variants in Patients with Pancreatic Neuroendocrine Tumors by Mohindroo, Chirayu, Baydogan, Seyda, Agarwal, Parul, Wright, Robin D, Prakash, Laura R, Mork, Maureen E, Klein, Alison P, Laheru, Daniel A, Maxwell, Jessica E, Katz, Matthew H G, Dasari, Arvind, Kim, Michael P, He, Jin, McAllister, Florencia, De Jesus-Acosta, Ana

“…Ten percent of pancreatic neuroendocrine tumors (pNET) are related to inherited syndromes (MEN1, MEN4, VHL, NF1, and TSC). Growing evidence suggests that…”
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Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial by Woo, Janghee, Zhai, Tingting, Yang, Fang, Xu, Huilei, Healey, Margaret L, Yates, Denise P, Beste, Michael T, Steensma, David P

“…Clonal hematopoiesis (CH) is more common in older persons and has been associated with an increased risk of hematological cancers and cardiovascular diseases…”
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Fenretinide in Young Women at Genetic or Familial Risk of Breast Cancer: A Placebo-Controlled Biomarker Trial by Aristarco, Valentina, Serrano, Davide, Maisonneuve, Patrick, Guerrieri-Gonzaga, Aliana, Lazzeroni, Matteo, Feroce, Irene, Macis, Debora, Cavadini, Elena, Albertazzi, Elena, Jemos, Costantino, Omodeo Salè, Emanuela, Cortesi, Laura, Massarut, Samuele, Gulisano, Marcella, Daidone, Maria Grazia, Johansson, Harriet, Bonanni, Bernardo

“…Fenretinide, a retinoid with a low-toxicity profile that accumulates in the breast, has been shown to prevent second breast cancer in young women. Fenretinide…”
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Multiyear Clinical Outcomes of Cancers Diagnosed Following Detection by a Blood-Based Multicancer Early Detection Test by Buchanan, Adam H, Lennon, Anne M, Choudhry, Omair A, Elias, Paul Z, Rego, Seema P, Sadler, Jennifer R, Roberta, Julia, Zhang, Yongqiang, Flake, 2nd, Darl D, Salvati, Zachary M, Wagner, Eric S, Fishman, Elliot K, Papadopoulos, Nickolas, Beer, Tomasz M

“…In the US, <20% of cancers are diagnosed by standard-of-care (SoC) screening. Multicancer early detection (MCED) tests offer the opportunity to expand cancer…”
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Preventive Treatment with a CD73 Small Molecule Inhibitor Enhances Immune Surveillance in K-Ras Mutant Pancreatic Intraepithelial Neoplasia by Strickland, Lincoln N, Liu, Wendao, Hussein, Usama, Mardik, Nicolette, Chen, Xian, Mills, Tingting, Vornik, Lana A, Savage, Michelle I, Sei, Shizuko, Clifford, John, Eltzschig, Holger K, Brown, Powel H, Zhao, Zhongming, McAllister, Florencia, Bailey-Lundberg, Jennifer M

“…Immunoprevention is an emerging consideration for solid tumors, including pancreatic ductal adenocarcinoma (PDAC). We and others have shown that Kras mutations…”
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Chemoprevention of Head and Neck Cancer: A Review of Current Approaches and Future Perspectives by Han, Sanghoon, Bommireddy, Ramireddy, Kim, Pauline, Selvaraj, Periasamy, Shin, Dong M

“…Head and neck squamous cell carcinoma (HNSCC) is a spectrum of heterogeneous malignancies. A variety of genetic, environmental, and lifestyle factors…”
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Lung Microbiome in Lung Cancer: A New Horizon in Cancer Study by Kashyap, Pragya, Dutt, Naveen, Ahirwar, Dinesh K, Yadav, Pankaj

“…Lung cancer is the second most prevalent cancer worldwide and a leading cause of cancer-related deaths. Recent technological advancements have revealed that…”
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Biomarker-Driven Personalized Immunoprevention: Toward More Efficient Clinical Trials? by Yendamuri, Sai, Dragnev, Konstantin H

“…In this secondary analysis of specimens from the CANTOS trial, the investigators find that patients with clonal hematopoiesis mutations, particularly in the…”
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