Search Results - "Cancer and metastasis reviews"

EMT, cell plasticity and metastasis by Chaffer, Christine L., San Juan, Beatriz P., Lim, Elgene, Weinberg, Robert A.

“…Carcinoma cells that are induced to suppress their epithelial features and upregulate mesenchymal gene expression programs acquire traits that promote an…”
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Applications of Raman spectroscopy in cancer diagnosis by Auner, Gregory W., Koya, S. Kiran, Huang, Changhe, Broadbent, Brandy, Trexler, Micaela, Auner, Zachary, Elias, Angela, Mehne, Katlyn Curtin, Brusatori, Michelle A.

“…Novel approaches toward understanding the evolution of disease can lead to the discovery of biomarkers that will enable better management of disease…”
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Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19? by Panigrahy, Dipak, Gilligan, Molly M., Huang, Sui, Gartung, Allison, Cortés-Puch, Irene, Sime, Patricia J., Phipps, Richard P., Serhan, Charles N., Hammock, Bruce D.

“…Severe coronavirus disease (COVID-19) is characterized by pulmonary hyper-inflammation and potentially life-threatening “cytokine storms”. Controlling the…”
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Causes, consequences, and therapy of tumors acidosis by Pillai, Smitha R., Damaghi, Mehdi, Marunaka, Yoshinori, Spugnini, Enrico Pierluigi, Fais, Stefano, Gillies, Robert J.

“…While cancer is commonly described as “a disease of the genes,” it is also associated with massive metabolic reprogramming that is now accepted as a disease…”
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PI3K/AKT/mTOR: role in breast cancer progression, drug resistance, and treatment by Guerrero-Zotano, Angel, Mayer, Ingrid A., Arteaga, Carlos L.

“…Anti-cancer cancer-targeted therapies are designed to exploit a particular vulnerability in the tumor, which in most cases results from its dependence on an…”
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Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review by Azmi, Asfar S., Bao, Bin, Sarkar, Fazlul H.

“…Trafficking of biological material across membranes is an evolutionary conserved mechanism and is part of any normal cell homeostasis. Such transport is…”
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RNA interference-based therapy and its delivery systems by Chen, Xiuhui, Mangala, Lingegowda S., Rodriguez-Aguayo, Cristian, Kong, Xianchao, Lopez-Berestein, Gabriel, Sood, Anil K.

“…RNA interference (RNAi) is considered a highly specific approach for gene silencing and holds tremendous potential for treatment of various pathologic…”
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The proteasome and proteasome inhibitors in multiple myeloma by Gandolfi, Sara, Laubach, Jacob P., Hideshima, Teru, Chauhan, Dharminder, Anderson, Kenneth C., Richardson, Paul G.

“…Proteasome inhibitors are one of the most important classes of agents to have emerged for the treatment of multiple myeloma in the past two decades, and now…”
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The Warburg metabolism fuels tumor metastasis by Lu, Jianrong

“…The Warburg effect is prevalent in human cancer. Accordingly, most cancer cells display highly elevated glycolysis without proportionally increasing pyruvate…”
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Glioma: molecular signature and crossroads with tumor microenvironment by Barthel, Lennart, Hadamitzky, Martin, Dammann, Philipp, Schedlowski, Manfred, Sure, Ulrich, Thakur, Basant Kumar, Hetze, Susann

“…In patients with glioblastoma, the average survival time with current treatments is short, mainly due to recurrences and resistance to therapy. This…”
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Hepatocellular carcinoma: molecular mechanism, targeted therapy, and biomarkers by Wang, Yu, Deng, Baocheng

“…Hepatocellular carcinoma (HCC) is a common malignancy and one of the leading causes of cancer-related death. The biological process of HCC is complex, with…”
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The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer by Hsu, Jennifer L., Hung, Mien-Chie

“…Breast cancer affects approximately 1 in 8 women, and it is estimated that over 246,660 women in the USA will be diagnosed with breast cancer in 2016. Breast…”
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Cancer-associated fibroblasts as key regulators of the breast cancer tumor microenvironment by Houthuijzen, J. M., Jonkers, J.

“…Tumor cells exist in close proximity with non-malignant cells. Extensive and multilayered crosstalk between tumor cells and stromal cells tailors the tumor…”
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Lung cancer identification: a review on detection and classification by Thakur, Shailesh Kumar, Singh, Dhirendra Pratap, Choudhary, Jaytrilok

“…Lung cancer is one of the most common diseases among humans and one of the major causes of growing mortality. Medical experts believe that diagnosing lung…”
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Update on gastric cancer treatments and gene therapies by Biagioni, Alessio, Skalamera, Ileana, Peri, Sara, Schiavone, Nicola, Cianchi, Fabio, Giommoni, Elisa, Magnelli, Lucia, Papucci, Laura

“…Gastric cancer is an active topic of clinical and basic research due to high morbidity and mortality. To date, gastrectomy and chemotherapy are the only…”
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Tumor pH and metastasis: a malignant process beyond hypoxia by Thews, Oliver, Riemann, Anne

“…Tumors often show, compared to normal tissues, a markedly decreased extracellular pH resulting from anaerobic or aerobic glycolysis in combination with a…”
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HER2 expression status in diverse cancers: review of results from 37,992 patients by Yan, Min, Schwaederle, Maria, Arguello, David, Millis, Sherri Z., Gatalica, Zoran, Kurzrock, Razelle

“…Human epidermal growth factor receptor 2 (HER2) amplification/overexpression is an effective therapeutic target in breast and gastric cancer. Although HER2…”
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miR-155 in cancer drug resistance and as target for miRNA-based therapeutics by Bayraktar, Recep, Van Roosbroeck, Katrien

“…Small non-coding microRNAs (miRNAs) are instrumental in physiological processes, such as proliferation, cell cycle, apoptosis, and differentiation, processes…”
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EGFR-targeted therapies in the post-genomic era by Xu, Mary Jue, Johnson, Daniel E., Grandis, Jennifer R.

“…Over 90% of head and neck cancers overexpress the epidermal growth factor receptor (EGFR). In diverse tumor types, EGFR overexpression has been associated with…”
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Stromal cells in tumor microenvironment and breast cancer by Mao, Yan, Keller, Evan T., Garfield, David H., Shen, Kunwei, Wang, Jianhua

“…Cancer is a systemic disease encompassing multiple components of both tumor cells themselves and host stromal cells. It is now clear that stromal cells in the…”
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