Search Results - "Canaud, Guillaume"

Inhibition of the mTORC Pathway in the Antiphospholipid Syndrome by Canaud, Guillaume, Bienaimé, Frank, Tabarin, Fanny, Bataillon, Guillaume, Seilhean, Danielle, Noël, Laure-Hélène, Dragon-Durey, Marie-Agnès, Snanoudj, Renaud, Friedlander, Gérard, Halbwachs-Mecarelli, Lise, Legendre, Christophe, Terzi, Fabiola

“…This study shows that the mTORC pathway is central to the antiphospholipid syndrome. Among patients with kidney transplants and antiphospholipid syndrome, 70%…”
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A review of mechanisms of disease across PIK3CA-related disorders with vascular manifestations by Canaud, Guillaume, Hammill, Adrienne M, Adams, Denise, Vikkula, Miikka, Keppler-Noreuil, Kim M

“…Abstract Background PIK3CA -related disorders include vascular malformations and overgrowth of various tissues that are caused by postzygotic, somatic variants…”
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AKT2 is essential to maintain podocyte viability and function during chronic kidney disease by Canaud, Guillaume, Bienaimé, Frank, Viau, Amandine, Treins, Caroline, Baron, William, Nguyen, Clément, Burtin, Martine, Berissi, Sophie, Giannakakis, Konstantinos, Muda, Andrea Onetti, Zschiedrich, Stefan, Huber, Tobias B, Friedlander, Gérard, Legendre, Christophe, Pontoglio, Marco, Pende, Mario, Terzi, Fabiola

“…Rapamycin (also known as sirolimus) is a potent immunosuppressive drug that is often used after organ transplant to prevent rejection, but it also can cause…”
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A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation by Delville, Marianne, Sigdel, Tara K, Wei, Changli, Li, Jing, Hsieh, Szu-Chuan, Fornoni, Alessia, Burke, George W, Bruneval, Patrick, Naesens, Maarten, Jackson, Annette, Alachkar, Nada, Canaud, Guillaume, Legendre, Christophe, Anglicheau, Dany, Reiser, Jochen, Sarwal, Minnie M

“…Recurrence of focal segmental glomerulosclerosis (rFSGS) after kidney transplantation is a cause of accelerated graft loss. To evaluate pathogenic antibodies…”
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Rituximab for Recurrence of Primary Focal Segmental Glomerulosclerosis After Kidney Transplantation: Clinical Outcomes by Garrouste, Cyril, Canaud, Guillaume, Büchler, Mathias, Rivalan, Joseph, Colosio, Charlotte, Martinez, Frank, Aniort, Julien, Dudreuilh, Caroline, Pereira, Bruno, Caillard, Sophie, Philipponnet, Carole, Anglicheau, Dany, Heng, Anne Elisabeth

“…BACKGROUNDRituximab has shown encouraging results for the treatment of kidney transplantation recipients with focal segmental glomerulosclerosis (FSGS)…”
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Recurrence of Focal and Segmental Glomerulosclerosis After Transplantation by Canaud, Guillaume, Delville, Marianne, Legendre, Christophe

“…ABSTRACTFocal segmental glomerulosclerosis, which is a common glomerular disorder, manifests clinically with a nephrotic syndrome and has a high propensity for…”
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INF2 Mutations in Charcot–Marie–Tooth Disease with Glomerulopathy by Boyer, Olivia, Nevo, Fabien, Plaisier, Emmanuelle, Funalot, Benoit, Gribouval, Olivier, Benoit, Geneviève, Cong, Evelyne Huynh, Arrondel, Christelle, Tête, Marie-Josèphe, Montjean, Rodrick, Richard, Laurence, Karras, Alexandre, Pouteil-Noble, Claire, Balafrej, Leila, Bonnardeaux, Alain, Canaud, Guillaume, Charasse, Christophe, Dantal, Jacques, Deschenes, Georges, Deteix, Patrice, Dubourg, Odile, Petiot, Philippe, Pouthier, Dominique, Leguern, Eric, Guiochon-Mantel, Anne, Broutin, Isabelle, Gubler, Marie-Claire, Saunier, Sophie, Ronco, Pierre, Vallat, Jean-Michel, Alonso, Miguel Angel, Antignac, Corinne, Mollet, Géraldine

“…The authors report that INF2 mutations are present in patients with focal segmental glomerulosclerosis (FSGS) associated with Charcot–Marie–Tooth neuropathy…”
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Temporal virus serological profiling of kidney graft recipients using VirScan by Isnard, Pierre, Kula, Tomasz, Fenoel, Véronique Avettand, Anglicheau, Dany, Terzi, Fabiola, Legendre, Christophe, Elledge, Stephen J., Canaud, Guillaume

“…At this time, pretransplant viral screening of donors and recipients is based on serological status and limited to certain viruses. After transplantation,…”
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A cystic and bullous lung disease associated with a PIK3CA-related overgrowth syndrome by Halitim, Pierre, Pastré, Jean, Mirault, Tristan, Canaud, Guillaume, Israël-Biet, Dominique

“…https://bit.ly/48GnoJy…”
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Activation of the PI3K/AKT/mTOR Pathway in Cajal-Retzius Cells Leads to Their Survival and Increases Susceptibility to Kainate-Induced Seizures by Ramezanidoraki, Nasim, Ouardi, Driss El, Le, Margaux, Moriceau, Stéphanie, Ahmadi, Mahboubeh, Elena, Dossi, Rolland, Danae, Bun, Philippe, Le Pen, Gwenaëlle, Canaud, Guillaume, Bahi-Buisson, Nadia, Rouach, Nathalie, Piskorowski, Rebecca, Pierani, Alessandra, Billuart, Pierre

“…Cajal-Retzius cells (CRs) are a class of transient neurons in the mammalian cortex that play a critical role in cortical development. Neocortical CRs undergo…”
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Unique presentation of a novel gain-of-function mutation in MTOR by Slimani, Samira, Gagnon, Alex G.I., Schreiber, Simon V., Bergeron, Nicolas A.D., Haydock, Ludwig, Labonté, Sébastien, Huot, Marc-Étienne, Garneau, Alexandre P., Canaud, Guillaume, Isenring, Paul

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Anticardiolipin antibodies and 12-month graft function in kidney transplant recipients: a prognosis cohort survey by Gauthier, Marion, Canoui-Poitrine, Florence, Guéry, Esther, Desvaux, Dominique, Hue, Sophie, Canaud, Guillaume, Stehle, Thomas, Lang, Philippe, Kofman, Tomek, Grimbert, Philippe, Matignon, Marie

“…In kidney transplant recipients, anticardiolipin (ACL) antibodies without antiphospholipid syndrome (APS) are found in up to 38% of patients and could be…”
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HIV-Positive–to–HIV-Positive Kidney Transplantation by Canaud, Guillaume, Avettand-Fenoel, Veronique, Legendre, Christophe, Fulco, Patricia P, Ho, Yu-Hui, Lu, Kevin, Muller, Elmi, Barday, Zunaid, Kahn, Delawir

“…To the Editor: Muller et al. (Feb. 12 issue) 1 report that among 27 patients with human immunodeficiency virus (HIV) infection who received kidneys from…”
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Targeted therapy for capillary-venous malformations by Zerbib, Lola, Ladraa, Sophia, Fraissenon, Antoine, Bayard, Charles, Firpion, Marina, Venot, Quitterie, Protic, Sanela, Hoguin, Clément, Thomas, Amandine, Fraitag, Sylvie, Duong, Jean-Paul, Kaltenbach, Sophie, Balducci, Estelle, Lefevre, Coline, Villarese, Patrick, Asnafi, Vahid, Broissand, Christine, Goudin, Nicolas, Nemazanyy, Ivan, Autret, Gwennhael, Tavitian, Bertrand, Legendre, Christophe, Arzouk, Nadia, Minard-Colin, Veronique, Chopinet, Caroline, Dussiot, Michael, Adams, Denise M., Mirault, Tristan, Guibaud, Laurent, Isenring, Paul, Canaud, Guillaume

“…Sporadic venous malformations are genetic conditions primarily caused by somatic gain-of-function mutation of PIK3CA or TEK , an endothelial transmembrane…”
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Minimal change nephrotic syndrome in patients infected with human immunodeficiency virus: a retrospective study of 8 cases by Arrestier, Romain, Satie, Anne-Pascale, Zhang, Shao-Yu, Plaisier, Emmanuelle, Isnard-Bagnis, Corinne, Gatault, Philippe, Raimbourg, Quentin, Buob, David, Vocila, Flavia, Heng, Anne-Elisabeth, Francois, Helene, Moktefi, Anissa, Canaud, Guillaume, Matignon, Marie, Dejucq-Rainsford, Nathalie, Brocheriou, Isabelle, Sahali, Dil, Audard, Vincent

“…Human immunodeficiency virus (HIV) is associated with diverse glomerular diseases. Characteristics of minimal change nephrotic syndrome (MCNS) in this setting…”
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V-ATPase/mTOR Signaling Regulates Megalin-Mediated Apical Endocytosis by Gleixner, Eva Maria, Canaud, Guillaume, Hermle, Tobias, Guida, Maria Clara, Kretz, Oliver, Helmstädter, Martin, Huber, Tobias B., Eimer, Stefan, Terzi, Fabiola, Simons, Matias

“…mTOR kinase is a master growth regulator that can be stimulated by multiple signals, including amino acids and the lysosomal small GTPase Rheb. Recent studies…”
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Treatment strategies for mosaic overgrowth syndromes of the PI3K-AKT-mTOR pathway by Morin, Gabriel, Canaud, Guillaume

“…Mosaic overgrowth syndromes (OS) are a proteiform ensemble of rare diseases displaying asymmetric overgrowth involving any tissue type, with degrees of…”
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PIK3CA-related overgrowth spectrum: animal model and drug discovery by Venot, Quitterie, Canaud, Guillaume

“…This review recapitulates the recent knowledge accumulation on overgrowth syndrome related to gain of function of the phosphoinositide3 kinase (PI3K)-alpha…”
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Therapeutic approach to focal and segmental glomerulosclerosis recurrence in kidney transplant recipients by Canaud, Guillaume, Martinez, Frank, Noël, Laure-Hélène, Mamzer, Marie-France, Niaudet, Patrick, Legendre, Christophe

“…Abstract Primary focal segmental glomerulosclerosis (FSGS) leads to end-stage renal disease in a high proportion of cases. The recurrence of FSGS after kidney…”
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Sotorasib for Vascular Malformations Associated with KRAS G12C Mutation. Reply by Fraissenon, Antoine, Guibaud, Laurent, Canaud, Guillaume

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