Search Results - "Can Çubukçu, Hikmet"

Effectiveness of Mesenchymal Stem Cell Therapy for COVID-19 Patients in the Intensive Care Unit: A Case-Control Study by Canbaz, Hayri, İdiz, Ufuk Oğuz, Cankar Dal, Hayriye, Kaçıroğlu, Fatih, Taş, Seher, Çubukçu, Hikmet Can, Beştemir, Attila, Gülşen, Murat, Polat, İstemi Taha, Laloğlu, Abubekir, Tör, İbrahim Hakkı, Akkurt, Halik Ekrem, Ateş, Utku, Reisli, İsmail, Koç, Esin, İnkaya, Ahmet Çağkan, Karakükçü, Musa, Ceylan, Mustafa, Haznedaroğlu, İbrahim Celalettin, Akın, Haluk

“…Many methods are used in the treatment of coronavirus disease 2019 (COVID-19), which causes acute respiratory distress syndrome (ARDS), and there are…”
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Machine learning-based clinical decision support using laboratory data by Çubukçu, Hikmet Can, Topcu, Deniz İlhan, Yenice, Sedef

“…Artificial intelligence (AI) and machine learning (ML) are becoming vital in laboratory medicine and the broader context of healthcare. In this review article,…”
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Detection of COVID-19 by Machine Learning Using Routine Laboratory Tests by Çubukçu, Hikmet Can, Topcu, Deniz İlhan, Bayraktar, Nilüfer, Gülşen, Murat, Sarı, Nuran, Arslan, Ayşe Hande

“…Abstract Objectives The present study aimed to develop a clinical decision support tool to assist coronavirus disease 2019 (COVID-19) diagnoses with machine…”
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Performance evaluation of internal quality control rules, EWMA, CUSUM, and the novel machine learning model by Çubukçu, Hikmet Can

“…The present study set out to build a machine learning model to incorporate conventional quality control (QC) rules, exponentially weighted moving average…”
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Estimation of Low-Density Lipoprotein Cholesterol Concentration Using Machine Learning by Çubukçu, Hikmet Can, Topcu, Deniz İlhan

“…Abstract Objective Low-density lipoprotein cholesterol (LDL-C) can be estimated using the Friedewald and Martin-Hopkins formulas. We developed LDL-C prediction…”
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An approach for determining allowable between reagent lot variation by van Schrojenstein Lantman, Marith, Çubukçu, Hikmet Can, Boursier, Guilaine, Panteghini, Mauro, Bernabeu-Andreu, Francisco A, Milinkovic, Neda, Mesko Brguljan, Pika, Linko, Solveig, Brugnoni, Duilio, O'Kelly, Ruth, Kroupis, Christos, Lohmander, Maria, Šprongl, Luděk, Vanstapel, Florent, Thelen, Marc

“…Clinicians trust medical laboratories to provide reliable results on which they rely for clinical decisions. Laboratories fulfil their responsibility for…”
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Voluntary imitation of dynamic facial expressions in attention deficit hyperactivity disorder: a facial-behavior analysis by Yildirim Demİrdöğen, Esen, Turan, Bahadır, Gülşen, Murat, Çubukçu, Hikmet Can, Dursun, Onur Burak

“…The difficulties involved in social interaction among children with attention deficit hyperactivity disorder (ADHD) have been shown in many studies. Based on…”
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Effects of cigarette smoke on oxidant-antioxidant system of lung tissue by Çubukçu, Hikmet Can, Durak, İlker

“…The present study set out to investigate the effects of cigarette smoke on oxidant-antioxidant systems of homogenized bovine lung tissue and the possible…”
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Ex vivo expansion of natural killer cells for hematological cancer immunotherapy: a systematic review and meta-analysis by Çubukçu, Hikmet Can, Mesutoğlu, Pınar Yurdakul, Seval, Güldane Cengiz, Beksaç, Meral

“…The present systematic review aimed to investigate natural killer (NK) cell ex vivo expansion protocols within the scope of clinical trials targeting…”
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Different effects of heating and freezing treatments on the antioxidant properties of broccoli, cauliflower, garlic and onion. An experimental in vitro study by Çubukçu, Hikmet Can, Kılıçaslan, Nazlı Seda Durak, Durak, İlker

“…Vegetables have some beneficial effects on human health due to their antioxidant compounds, like polyphenols. Cooking leads to many physical and chemical…”
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The trade-off between bias and imprecision: Debunking the myth of bias as the primary culprit in patient result misclassification by Çubukçu, Hikmet Can

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Optimization of patient-based real-time quality control based on the Youden index by İlhan Topcu, Deniz, Can Çubukçu, Hikmet

“…•EWMA is a PBRTQC tool that provides efficient and continuous monitoring.•Optimization of EWMA features is important for an effective EWMA application.•Youden…”
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Validation of SMA screening kits with SMN1 gene analysis in a Turkish cohort by Gülşen, Murat, Ceylan, Ahmet Cevdet, Bahsi, Taha, Çubukçu, Hikmet Can, Dursun, Onur Burak

“…•Quantitative Real-Time Polymerase Chain Reaction validated against MLPA for Spinal Muscular Atrophy screening.•Analysis showed high accuracy of qRT-PCR…”
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False negative results and tolerance limits of SARS-CoV-2 laboratory tests by Çubukçu, Hikmet Can, Coşkun, Abdurrahman

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The weighting factor of exponentially weighted moving average chart by Çubukçu, Hikmet Can

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Measuring the impact: Severity of harm from laboratory errors in 195 tests by Çubukçu, Hikmet Can, Cihan, Murat, Alp, Hamit Hakan, Bolat, Serkan, Zengi, Oğuzhan, Uçar, Kamil Taha, Topcu, Deniz İlhan, Kılınçkaya, Muhammed Fevzi, Özdemir, Habib, Gülşen, Murat, Canbaz, Hayri, Yücel, Doğan, Serdar, Muhittin Abdulkadir

“…This study aimed to objectively assess the potential severity of harm associated with erroneous results in 195 laboratory tests by surveying 514 specialist…”
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Toward the detection of reduced emotion expression intensity: an autism sibling study by Turan, Bahadir, Algedik Demirayak, Pinar, Yildirim Demirdogen, Esen, Gulsen, Murat, Cubukcu, Hikmet Can, Guler, Muhammed, Alarslan, Hatice, Yilmaz, Asım Egemen, Dursun, Onur Burak

“…Expressing emotions through spontaneous facial expression is an important nonverbal social communication skill. In our study, we aimed to demonstrate that both…”
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ISO 15189 is a sufficient instrument to guarantee high-quality manufacture of laboratory developed tests for in-house-use conform requirements of the European In-Vitro -Diagnostics Regulation by Vanstapel, Florent J L A, Orth, Matthias, Streichert, Thomas, Capoluongo, Ettore D, Oosterhuis, Wytze P, Çubukçu, Hikmet Can, Bernabeu-Andreu, Francisco A, Thelen, Marc, Jacobs, Leo H J, Linko, Solveig, Bhattoa, Harjit Pal, Bossuyt, Patrick M M, Meško Brguljan, Pika, Boursier, Guilaine, Cobbaert, Christa M, Neumaier, Michael

“…The EU Diagnostic Device Regulation (IVDR) aims for transparent risk-and purpose-based validation of diagnostic devices, traceability of results to uniquely…”
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Improper coverage factor to compare expanded uncertainty with allowable total error by Çubukçu, Hikmet Can

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Improving the laboratory result release process in the light of ISO 15189:2012 standard by Can Çubukçu, Hikmet, Vanstapel, Florent, Thelen, Marc, Bernabeu-Andreu, Francisco A., van Schrojenstein Lantman, Marith, Brugnoni, Duilio, Mesko Brguljan, Pika, Milinkovic, Neda, Linko, Solveig, Vaubourdolle, Michel, O'Kelly, Ruth, Kroupis, Christos, Lohmander, Maria, Šprongl, Luděk, Panteghini, Mauro, Boursier, Guilaine

“…The ISO 15189:2012 standard section 5.9.1 requires laboratories to review results before release, considering quality control, previous results, and clinical…”
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