Search Results - "Can, Özgür"
-
1
The water soluble Zn(II) and Mg(II) phthalocyanines: Synthesis, photochemical, DNA photodamage and PDT effects against A549 cells
Published in Journal of photochemistry and photobiology. A, Chemistry. (15-01-2021)“…[Display omitted] •Synthesis of water soluble ZnPcQ and MgPcQ.•The singlet oxygen quantum yield of ZnPcQ is 0.59.•Photonuclease properties of water soluble…”
Get full text
Journal Article -
2
Non-aggregated axially disubstituted silicon phthalocyanines: Synthesis, DNA cleavage and in vitro cytotoxic/phototoxic anticancer activities against SH-SY5Y cell line
Published in Dyes and pigments (01-01-2020)“…In this paper, axially {6-[3-(dimethylamino)phenoxy]hexyl}oxy and {6-[3-(diethylamino)phenoxy]hexyl}oxy groups substituted silicon phthalocyanines were…”
Get full text
Journal Article -
3
Risk factors for infection and mortality among hemodialysis patients during COVID-19 pandemic
Published in International urology and nephrology (01-03-2022)“…Purpose The aim of this study was to evaluate risk factors for COVID-19 infection and mortality and to document if any relation exists between 25 (OH) Vitamin…”
Get full text
Journal Article -
4
DNA interaction, cytotoxic and phototoxic properties of new water‐soluble zinc (II) phthalocyanines
Published in Applied organometallic chemistry (01-12-2022)“…In this paper, we have synthesized water‐soluble peripherally tetra and octa‐({6‐[3‐(dimethylamino)phenoxy]hexyl}oxy) groups substituted zinc (II)…”
Get full text
Journal Article -
5
Synthesis and evaluation of new 1,5-diaryl-3-[4-(methyl-sulfonyl)phenyl]-4,5-dihydro-1H-pyrazole derivatives as potential antidepressant agents
Published in Molecules (Basel, Switzerland) (04-02-2015)“…In an effort to develop potent antidepressant agents, new pyrazoline derivatives 2a-s were synthesized and evaluated for their antidepressant-like activity by…”
Get full text
Journal Article -
6
Peripheral or nonperipheral tetra‐[4‐(9H‐carbazol‐9‐yl)phenoxy] substituted cobalt(II), manganese(III) phthalocyanines: Synthesis, acetylcholinesterase, butyrylcholinesterase, and α‐glucosidase inhibitory effects and anticancer activities
Published in Applied organometallic chemistry (01-01-2021)“…In this work, peripheral or nonperipheral tetra‐[4‐(9H‐carbazol‐9‐yl)phenoxy] substituted cobalt(II), manganese (III) phthalocyanines were synthesized for the…”
Get full text
Journal Article -
7
CRISPR-Cas13 System as a Promising and Versatile Tool for Cancer Diagnosis, Therapy, and Research
Published in ACS synthetic biology (18-06-2021)“…Over the past decades, significant progress has been made in targeted cancer therapy. In precision oncology, molecular profiling of cancer patients enables the…”
Get full text
Journal Article -
8
Evaluation of photodynamic therapy effects of novel zinc (II) phthalocyanine through a possible interaction with toll‐like receptor signaling pathway
Published in Applied organometallic chemistry (01-04-2023)“…In this work, 3‐({6‐[3‐(dimethylamino)phenoxy]hexyl}oxy)phthalonitrile (2) and the target zinc (II) phthalocyanine (3) and its ammonium derivative (3a) are…”
Get full text
Journal Article -
9
In vitro cholinesterases, tyrosinase, α-glucosidase inhibitory and anticancer effects of novel silicon phthalocyanines containing geraniol/phytol
Published in Inorganic chemistry communications (01-07-2024)“…[Display omitted] •Synthesis of axially geraniol/phytol disubstituted silicon (IV) phthalocyanines.•Cytotoxic effects on L-929 cells of silicon (IV)…”
Get full text
Journal Article -
10
Synthesis and Antidepressant Activity Profile of Some Novel Benzothiazole Derivatives
Published in Molecules (Basel, Switzerland) (07-09-2017)“…Within the scope of our new antidepressant drug development efforts, in this study, we synthesized eight novel benzothiazole derivatives - . The chemical…”
Get full text
Journal Article -
11
Axially disubstituted silicon (IV) phthalocyanines containing different isoxazolyl groups: Design, syntheses, binding and in vitro phototoxic activities against SH-SY5Y cells
Published in Journal of molecular structure (15-08-2022)“…•Synthesis of silicon (IV) phthalocyanines containing different isoxazolyl groups.•In vitro phototoxic activities against SH-SY5Y cells of silicon (IV)…”
Get full text
Journal Article -
12
Synthesis of water‐soluble BODIPY dyes and investigation of their DNA interaction properties and cytotoxicity/phototoxicity
Published in Applied organometallic chemistry (01-11-2021)“…In this study, water‐soluble BODIPY dyes (BDPY‐4, BDPY‐5) bearing dimethylamino and diethylamino groups were synthesized for the first time. The DNA…”
Get full text
Journal Article -
13
Synthesis of Some Novel Thiadiazole Derivative Compounds and Screening Their Antidepressant-Like Activities
Published in Molecules (Basel, Switzerland) (21-03-2018)“…Novel thiadiazole derivatives were synthesized through the reaction of acetylated 2-aminothiadiazole and piperazine derivatives. The chemical structures of the…”
Get full text
Journal Article -
14
Opioid system mediated anti-nociceptive effect of agomelatine in mice
Published in Life sciences (1973) (15-10-2016)“…This study was planned to examine the antinociceptive efficacy of agomelatine against acute mechanical, thermal, and chemical nociceptive stimuli, as well as…”
Get full text
Journal Article -
15
Anti-depressant-like effect of vitexin in BALB/c mice and evidence for the involvement of monoaminergic mechanisms
Published in European journal of pharmacology (15-01-2013)“…The present study was designed to investigate the putative effect of vitexin, a flavone C–glucoside present in some drugs, medicinal plants and nutraceuticals,…”
Get full text
Journal Article -
16
Photochemical and in vitro phototoxic properties of Zn (II) phthalocyanine bearing piperidinium groups on different cell lines
Published in Journal of organometallic chemistry (15-08-2020)“…In present work, the photochemical effects (singlet oxygen quantum yield (ΦΔ) and photodegradation quantum yield (Φd)) of the peripherally tetra…”
Get full text
Journal Article -
17
Synthesis, DNA interaction, in vitro/in silico topoisomerase II inhibition and photodynamic therapy activities of two cationic BODIPY derivatives
Published in Dyes and pigments (01-03-2020)“…A new series of BODIPY 3 and 6 with two dimethylamino and diethylamino moieties at their 3,5-positions were prepared via Knoevenagel condensation of BODIPY 2…”
Get full text
Journal Article -
18
Design, synthesis, and AChE inhibitory activity of new benzothiazole–piperazines
Published in Bioorganic & medicinal chemistry letters (15-11-2016)“…Fourteen new benzothiazole–piparazines were designed and synthesised in order to investigate their AChE inhibition potency. Characterised compounds were…”
Get full text
Journal Article -
19
-
20
Antiamnesic effects of tofisopam against scopolamine-induced cognitive impairments in rats
Published in Pharmacology, biochemistry and behavior (01-03-2020)“…In this study, we investigated the potential therapeutic effects of tofisopam, a 2,3-benzodiazepine derivative anxiolytic, on cognitive deficits in rats with…”
Get full text
Journal Article