Search Results - "Camps, Marcel Gm"

Tumor-draining lymph nodes are pivotal in PD-1/PD-L1 checkpoint therapy by Fransen, Marieke F, Schoonderwoerd, Mark, Knopf, Philipp, Camps, Marcel Gm, Hawinkels, Lukas Jac, Kneilling, Manfred, van Hall, Thorbald, Ossendorp, Ferry

“…PD-1/PD-L1 checkpoint therapy for cancer is commonly considered to act by reactivating T cells in the tumor microenvironment. Here, we present data from 2…”
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C1q-Dependent Dendritic Cell Cross-Presentation of In Vivo-Formed Antigen-Antibody Complexes by Ho, Nataschja I, Camps, Marcel G M, de Haas, Edwin F E, Trouw, Leendert A, Verbeek, J Sjef, Ossendorp, Ferry

“…Dendritic cells (DCs) are specialized in Ag engulfment via a wide variety of uptake receptors on their cell surface. In the present study we investigated Ag…”
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Fcγ receptor IIb strongly regulates Fcγ receptor-facilitated T cell activation by dendritic cells by van Montfoort, Nadine, 't Hoen, Peter A C, Mangsbo, Sara M, Camps, Marcel G M, Boross, Peter, Melief, Cornelis J M, Ossendorp, Ferry, Verbeek, J Sjef

“…FcγR ligation by Ag-Ab immune complexes (IC) not only mediates effective Ag uptake, but also strongly initiates dendritic cell (DC) maturation, a requirement…”
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Effect of vesicle size on tissue localization and immunogenicity of liposomal DNA vaccines by Carstens, Myrra G, Camps, Marcel G.M, Henriksen-Lacey, Malou, Franken, Kees, Ottenhoff, Tom H.M, Perrie, Yvonne, Bouwstra, Joke A, Ossendorp, Ferry, Jiskoot, Wim

“…Abstract The formulation of plasmid DNA (pDNA) in cationic liposomes is a promising strategy to improve the potency of DNA vaccines. In this respect,…”
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Multiantigen pan-sarbecovirus DNA vaccines generate protective T cell immune responses by van Bergen, Jeroen, Camps, Marcel Gm, Pardieck, Iris N, Veerkamp, Dominique, Leung, Wing Yan, Leijs, Anouk A, Myeni, Sebenzile K, Kikkert, Marjolein, Arens, Ramon, Zondag, Gerben C, Ossendorp, Ferry

“…SARS-CoV-2 is the third zoonotic coronavirus to cause a major outbreak in humans in recent years, and many more SARS-like coronaviruses with pandemic potential…”
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A Novel Role of Complement Factor C1q in Augmenting the Presentation of Antigen Captured in Immune Complexes to CD8 super(+) T Lymphocytes by van Montfoort, Nadine, de Jong, Judith MH, Schuurhuis, Danita H, van der Voort, Ellen IH, Camps, Marcel GM, Huizinga, Tom WJ, van Kooten, Cees, Daha, Mohamed R, Verbeek, JSjef, Ossendorp, Ferry, Toes, Rene EM

“…Ag-IgG immune complexes (IC) are efficiently taken up, and Ag-derived peptides are subsequently processed and presented by APC. In vitro experiments indicate…”
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ORIGINAL ARTICLE: Dendritic cells, but not macrophages or B cells, activate major histocompatibility complex class II-restricted CD4 super(+) T cells upon immune-complex uptake in vivo by de Jong, Judith MH, Schuurhuis, Danita H, Ioan-Facsinay, Andreea, Welling, Mick M, Camps, Marcel GM, van der Voort, Ellen IH, Huizinga, Tom WJ, Ossendorp, Ferry, Verbeek, JSjef, Toes, Rene EM

“…Professional antigen-presenting cells (APC) are able to process and present exogenous antigen leading to the activation of T cells. Antigen-immunoglobulin…”
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