Search Results - "Campos Toimil, M"

Short‐term or long‐term treatments with a phosphodiesterase‐4 (PDE4) inhibitor result in opposing agonist‐induced Ca2+ responses in endothelial cells by Campos‐Toimil, M, Keravis, T, Orallo, F, Takeda, K, Lugnier, C

“…Background and purpose: We previously reported that agonist‐induced rises in cytoplasmic Ca2+ concentration ([Ca2+]i) in human umbilical vein endothelial cells…”
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Short-term or long-term treatments with a phosphodiesterase-4 (PDE4) inhibitor result in opposing agonist-induced Ca(2+) responses in endothelial cells by Campos-Toimil, M, Keravis, T, Orallo, F, Takeda, K, Lugnier, C

“…We previously reported that agonist-induced rises in cytoplasmic Ca(2+) concentration ([Ca(2+)](i)) in human umbilical vein endothelial cells (HUVEC) were…”
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Role of tobacco vs alcohol, in intracellular calcium levels and enzyme secretion in pancreatic acinar cells by Luaces-Regueira, M, Castiñeira-Alvariño, M, Castro-Manzanares, M, Carrascal-Miniño, A, Campos-Toimil, M, Domínguez-Muñoz, J.E

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Intracellular calcium levels and enzyme secretion in response to tobacco vs ethanol in pancreatic acinar cells by Luaces-Regueira, M, Castiñeira-Alvariño, M, Castro-Manzanares, M, Carrascal-Miniño, A, Campos-Toimil, M, Domínguez-Muñoz, J.E

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Real-time studies of zymogen granule exocytosis in intact rat pancreatic acinar cells by Campos-Toimil, M, Edwardson, J M, Thomas, P

“…An adequate understanding of secretion requires the measurement of exocytosis on the same time scale as that used for second messenger dynamics. To investigate…”
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Inhibition of Type 4 Phosphodiesterase by Rolipram and Ginkgo biloba Extract (EGb 761) Decreases Agonist-Induced Rises in Internal Calcium in Human Endothelial Cells by Campos-Toimil, Manuel, Lugnier, Claire, Droy-Lefaix, Marie-Thérèse, Takeda, Kenneth

“…The effects of Gingko biloba extract EGb 761 on 5 isolated, vascular, cyclic nucleotide phosphodiesterase (PDE) isoforms were evaluated. EGb 761 preferentially…”
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Short‐term or long‐term treatments with a phosphodiesterase‐4 (PDE4) inhibitor result in opposing agonist‐induced Ca 2+ responses in endothelial cells by Campos‐Toimil, M, Keravis, T, Orallo, F, Takeda, K, Lugnier, C

“…Background and purpose: We previously reported that agonist‐induced rises in cytoplasmic Ca 2+ concentration ([Ca 2+ ] i ) in human umbilical vein endothelial…”
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Synthesis and Vasorelaxant Activity of New Coumarin and Furocoumarin Derivatives by Campos-Toimil, Manuel, Orallo, Francisco, Santana, Lourdes, Uriarte, Eugenio

“…We have synthesized a new series of coumarins and furocoumarins and evaluated their vasorelaxant activity in rat aorta rings pre-contracted with noradrenaline…”
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Short-term or long-term treatments with a phosphodiesterase-4 (PDE4) inhibitor result in opposing agonist-induced Ca super(2+) responses in endothelial cells by Campos-Toimil, M, Keravis, T, Orallo, F, Takeda, K, Lugnier, C

“…Background and purpose: We previously reported that agonist-induced rises in cytoplasmic Ca super(2+) concentration ([Ca super(2+)] sub(i)) in human umbilical…”
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Study of the mechanisms involved in the vasorelaxation induced by (-)-epigallocatechin gallate in rat aorta by Alvarez, E., Campos-Toimil, M., Justiniano-Basaran, H., Lugnier, C., Orallo, F.

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(-)-Epigallocatechin-3-gallate induces contraction of the rat aorta by a calcium influx-dependent mechanism by Alvarez-Castro, Ezequiel, Campos-Toimil, Manuel, Orallo, Francisco

“…Although the consumption of tea has been associated with beneficial cardiovascular effects, (-)-epigallocatechin-3-gallate (EGCG), the most abundant catechin…”
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Pyridazine derivatives XIV. Study of the vasorelaxant action of 6-aryl-5-piperidino-3-hydrazinopyridazines in isolated rat thoracic aorta: Comparison with hydralazine by Campos-Toimil, M., Estévez, I., Raviña, E., Orallo, F.

“…1. 1. For several years we have been working on the synthesis of modified hydrazinopyridazines which have proved to possess remarkable vasorelaxant and…”
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Migration of human vascular smooth muscle cells involves serum-dependent repeated cytosolic calcium transients by Scherberich, A, Campos-Toimil, M, Rondé, P, Takeda, K, Beretz, A

“…Migration of vascular smooth muscle cells (VSMC) is a key event in the formation of neointima during atherosclerosis. Fura-2 loaded VSMCs were used to…”
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Two Modes of Secretion in Pancreatic Acinar Cells: Involvement of Phosphatidylinositol 3-Kinase and Regulation by Capacitative Ca super(2+) Entry by Campos-Toimil, M, Bagrij, T, Edwardson, J M, Thomas, P

“…In pancreatic acinar cells, muscarinic agonists stimulate both the release of Ca super(2+) from intracellular stores and the influx of extracellular Ca…”
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Mitochondria play a critical role in shaping the exocytotic response of rat pancreatic acinar cells by Thomas, Paul, Bagrij, Tanya, Campos-Toimil, Manuel, Edwardson, J. Michael

“…We have previously demonstrated [M. Campos-Toimil, T. Bagrij, J.M. Edwardson, P. Thomas, Two modes of secretion in pancreatic acinar cells: involvement of…”
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Two Modes of Secretion in Pancreatic Acinar Cells: Involvement of Phosphatidylinositol 3-Kinase and Regulation by Capacitative Ca2+ Entry by Campos-Toimil, Manuel, Bagrij, Tanya, Edwardson, J.Michael, Thomas, Paul

“…In pancreatic acinar cells, muscarinic agonists stimulate both the release of Ca2+ from intracellular stores and the influx of extracellular Ca2+. The part…”
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Synthesis and pharmacological evaluation of 2,3-dihydro-3-oxo-4H-thieno[3,4-e][1,2,4]thiadiazine 1,1-dioxides as voltage-dependent calcium channel blockers by ARRANZ, E, DIAZ, J. A, VEGA, S, CAMPOS-TOIMIL, M, ORALLO, F, CARDELUS, I, LLENAS, J, FERNANDEZ, A. G

“…The synthesis of a novel series of 2,3-dihydro-3-oxo-4H-thieno[3, 4-e][1,2,4]thiadiazine 1,1-dioxides and their pharmacological evaluation as drugs with…”
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Study of the in vivo and in vitro cardiovascular effects of (+)‐glaucine and N‐carbethoxysecoglaucine in rats by Orallo, Francisco, Alzueta, Alejandro Fdez, Campos‐Toimil, Manuel, Calleja, José Ma

“…1 The cardiovascular and vasorelaxant effects of (+)‐glaucine and of a semisynthetic derivative (N‐carbethoxysecoglaucine) were studied in rats. 2…”
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Pharmacological study of several effects of hydralazine in the bisected rat vas deferens by Campos-Toimil, M, Orallo, F, Gil-Longo, J, Verde, I, Loza, I, Fernández-Alzueta, A

“…We have studied several effects of hydralazine in the bisected rat vas deferens. Hydralazine produced a shift to the left of the concentration-response curve…”
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Acetylcholine-induced zymogen granule exocytosis: Comparison between acini and single pancreatic acinar cells by CAMPOS-TOIMIL, Manuel, EDWARDSON, J. Michael, THOMAS, Paul

“…Numerous studies have been carried out on the agonist-evoked calcium responses of single pancreatic acinar cells; however, several reports have shown that…”
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