Search Results - "Campos Granato, Daniela"
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Interactome analysis of the human Cap‐specific mRNA (nucleoside‐2′‐O‐)‐methyltransferase 1 (hMTr1) protein
Published in Journal of cellular biochemistry (01-04-2019)“…In a previous study, we have shown that the gene promoter of a protein termed KIAA0082 is regulated by interferon and that this protein interacts with the RNA…”
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Agrin has a pathological role in the progression of oral cancer
Published in British journal of cancer (01-06-2018)“…Background The extracellular matrix modulates the hallmarks of cancer. Here we examined the role of agrin—a member of this matrix—in progression of oral…”
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Mass spectrometry-based proteomics revealed Glypican-1 as a novel ADAM17 substrate
Published in Journal of proteomics (16-01-2017)“…ADAM17 (a disintegrin and metalloproteinase 17) is a plasma membrane metalloprotease involved in proteolytic release of the extracellular domain of many cell…”
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NEK1 kinase domain structure and its dynamic protein interactome after exposure to Cisplatin
Published in Scientific reports (14-07-2017)“…NEK family kinases are serine/threonine kinases that have been functionally implicated in the regulation of the disjunction of the centrosome, the assembly of…”
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A meta-analysis reveals the protein profile associated with malignant transformation of oral leukoplakia
Published in Frontiers in oral health (27-02-2023)“…The search for biomarkers associated with oral leukoplakia malignant transformation is critical for early diagnosis and improved prognosis of oral cancer…”
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Structural analysis of intermolecular interactions in the kinesin adaptor complex fasciculation and elongation protein zeta 1/ short coiled-coil protein (FEZ1/SCOCO)
Published in PloS one (07-10-2013)“…Cytoskeleton and protein trafficking processes, including vesicle transport to synapses, are key processes in neuronal differentiation and axon outgrowth. The…”
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Uncovering the bookshelves of CRISPR-based libraries: Advances and applications in cancer studies
Published in Critical reviews in oncology/hematology (01-04-2024)“…The advent of CRISPR/Cas9 technology has revolutionized the genome editing field. CRISPR-based libraries have become powerful tools for high-throughput…”
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Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer
Published in Nature communications (05-09-2018)“…Different regions of oral squamous cell carcinoma (OSCC) have particular histopathological and molecular characteristics limiting the standard…”
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NONINVASIVE LIQUID BIOPSY OF TEAR FLUIDS MAY REFLECT ORAL CANCER INITIATION
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01-06-2024)“…We aimed to find biomarkers of progression from oral leukoplakias (OL) to oral squamous cell carcinoma (OSCC) using the noninvasive liquid biopsy of tear…”
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MOLECULAR PROFILING OF TEAR FLUIDS REVEALS SIGNATURES OF MALIGNANT TRANSFORMATION INTO ORAL CANCER
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01-07-2023)“…We aimed to find biological signatures of malignant transformation using non-invasive liquid biopsy. Unstimulated tears from patients with OL (N=10), PVL…”
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Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways
Published in International journal of oncology (01-06-2021)“…Lung cancer is the leading cause of cancer-associated death worldwide and exhibits intrinsic and acquired therapeutic resistance to cisplatin (CIS). The…”
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A Reductionist Approach Using Primary and Metastatic Cell–Derived Extracellular Vesicles Reveals Hub Proteins Associated with Oral Cancer Prognosis
Published in Molecular & cellular proteomics (01-01-2021)“…Oral squamous cell carcinoma (OSCC) has high mortality rates that are largely associated with lymph node metastasis. However, the molecular mechanisms that…”
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Abstract 4542: The use of saliva proteins as biomarkers to predict the risk of lymph node metastasis in oral cancer
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Background. The most common oral cancer in the world is squamous cell carcinoma (OSCC), accounting for more than 90% of all cases of cancer in the oral cavity…”
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Follistatin-related protein 1 interacting partner of Syndecan-1 promotes an aggressive phenotype on Oral Squamous cell carcinoma (OSCC) models
Published in Journal of proteomics (15-03-2022)“…Syndecans belong to the family of transmembrane heparan sulfate proteoglycans and are associated with many physiopathological processes, including oral cancer…”
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Corrigendum to: "Follistatin-related protein 1 interacting partner of Syndecan-1 promotes an aggressive phenotype on Oral Squamous cell carcinoma (OSCC) models" [J Proteomics. 2022 Jan 3:104474. doi: 10.1016/j.jprot.2021.104474. Online ahead of print. PMID: 34990821]
Published in Journal of proteomics (30-04-2022)Get full text
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STAT3 contributes to cisplatin resistance, modulating EMT markers, and the mTOR signaling in lung adenocarcinoma
Published in Neoplasia (New York, N.Y.) (01-10-2021)“…•SILAC proteomics approach yielded important cisplatin resistance biomarkers in NSCLC.•Cisplatin resistance upregulated NER-based repair and downregulated mRNA…”
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Proteomic approaches to assist in diagnosis and prognosis of oral cancer
Published in Expert review of proteomics (03-04-2021)“…Oral squamous cell carcinoma (OSCC) ranks among the top 10 leading causes of cancer worldwide, with 5-year survival rate of about 50%, high lymph node…”
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N-terminal phosphorylation of glutaminase C decreases its enzymatic activity and cancer cell migration
Published in Biochimie (01-11-2018)“…The mitochondrial phosphate-activated glutaminase C (GAC) is produced by the alternative splicing of the GLS gene. Compared to the other GLS isoform, the…”
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Crystal Structure and Regulation of the Citrus Pol III Repressor MAF1 by Auxin and Phosphorylation
Published in Structure (London) (05-09-2017)“…MAF1 is the main RNA polymerase (Pol) III repressor that controls cell growth in eukaryotes. The Citrus ortholog, CsMAF1, was shown to restrict cell growth in…”
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Hydrocephalus and arthrogryposis in an immunocompetent mouse model of ZIKA teratogeny: A developmental study
Published in PLoS neglected tropical diseases (23-02-2017)“…The teratogenic mechanisms triggered by ZIKV are still obscure due to the lack of a suitable animal model. Here we present a mouse model of developmental…”
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