Search Results - "Campos‐Pérez, Francisco"
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Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis
Published in Molecular cell (08-08-2019)“…Cell-cell communication via ligand-receptor signaling is a fundamental feature of complex organs. Despite this, the global landscape of intercellular signaling…”
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The Genetic Architecture of Diet‐Induced Hepatic Fibrosis in Mice
Published in Hepatology (Baltimore, Md.) (01-12-2018)“…We report the genetic analysis of a “humanized” hyperlipidemic mouse model for progressive nonalcoholic steatohepatitis (NASH) and fibrosis. Mice carrying…”
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Contribution of common genetic variants to obesity and obesity-related traits in mexican children and adults
Published in PloS one (08-08-2013)“…Several studies have identified multiple obesity-associated loci mainly in European populations. However, their contribution to obesity in other ethnicities…”
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PCSK1 rs6232 is associated with childhood and adult class III obesity in the Mexican population
Published in PloS one (21-06-2012)“…Common variants rs6232 and rs6235 in the PCSK1 gene have been associated with obesity in European populations. We aimed to evaluate the contribution of these…”
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Expression of adipokines and their receptors in adipose tissue of women with class 3 obesity with or without hypertension
Published in Gene (20-06-2019)“…Obesity increases the risk of developing hypertension. Since both pathological entities constitute public health problems, the aim of this study was to…”
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SFRP5 hepatic expression is associated with non-alcoholic liver disease in morbidly obese women
Published in Annals of hepatology (01-09-2015)“…AbstractBackground and aims. Secreted frizzled-related protein 5 (SFRP5) was recently described as a new adipokine protective for hepatic steatosis and other…”
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A combined linkage and association strategy identifies a variant near the GSTP1 gene associated with BMI in the Mexican population
Published in Journal of human genetics (01-03-2017)“…Obesity is a major public health concern in Mexico and worldwide. Although the estimated heritability is high, common variants identified by genome-wide…”
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Hepatic miR-33a/miR-144 and their target gene ABCA1 are associated with steatohepatitis in morbidly obese subjects
Published in Liver international (01-09-2016)“…Background and Aim Abnormal cholesterol metabolism may contribute to the pathogenesis of non‐alcoholic steatohepatitis (NASH) and fibrosis. miR‐33 and miR‐144…”
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Sustained blood glutamate scavenging enhances protection in ischemic stroke
Published in Communications biology (03-12-2020)“…Stroke is a major cause of morbidity, mortality, and disability. During ischemic stroke, a marked and prolonged rise of glutamate concentration in the brain…”
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A genetic risk score is associated with hepatic triglyceride content and non-alcoholic steatohepatitis in Mexicans with morbid obesity
Published in Experimental and molecular pathology (01-04-2015)“…Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) near/in PNPLA3, NCAN, LYPLAL1, PPP1R3B, and GCKR genes associated with…”
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Trimethylamine N-oxide levels are associated with NASH in obese subjects with type 2 diabetes
Published in Diabetes & metabolism (01-03-2021)“…Trimethylamine N-oxide (TMAO), choline and betaine serum levels have been associated with metabolic diseases including type 2 diabetes (T2D) and non-alcoholic…”
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Interaction between FTO rs9939609 and the Native American-origin ABCA1 rs9282541 affects BMI in the admixed Mexican population
Published in BMC medical genetics (02-05-2017)“…The aim of this study was to explore whether interactions between FTO rs9939609 and ABCA1 rs9282541 affect BMI and waist circumference (WC), and could explain…”
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Resolución de hernia abdominal con pérdida de domicilio en dos tiempos quirúrgicos, en un paciente con obesidad mórbida
Published in Cirugia y cirujanos (04-11-2021)“…La obesidad es un factor de riesgo para el desarrollo de hernias de la pared abdominal anterior. Las hernias incisionales se desarrollan hasta en el 13% de las…”
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