Search Results - "Campos, Vinícius R"
-
1
A new and efficient procedure for the synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones
Published in Beilstein journal of organic chemistry (22-07-2015)“…A new and efficient method for the synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones in one step with high yields from the reaction of lawsone with…”
Get full text
Journal Article -
2
Natural biflavonoids as potential therapeutic agents against microbial diseases
Published in The Science of the total environment (15-05-2021)“…Microbes broadly constitute several organisms like viruses, protozoa, bacteria, and fungi present in our biosphere. Fast-paced environmental changes have…”
Get full text
Journal Article -
3
Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors
Published in European journal of medicinal chemistry (01-01-2021)“…In this work, we designed and synthesized 35 new triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives as P. falciparum inhibitors (3D7 strain)…”
Get full text
Journal Article -
4
Synthesis and antimicrobial evaluation of amino sugar-based naphthoquinones and isoquinoline-5,8-diones and their halogenated compounds
Published in European journal of medicinal chemistry (05-08-2018)“…Antibiotic resistance has emerged as a serious global public health problem and lately very few antibiotics have been discovered and introduced into clinical…”
Get full text
Journal Article -
5
An Overview of Treatment Guidelines and Methods of Synthesis of Drugs Used in Leprosy Chemotherapy
Published in Mini reviews in medicinal chemistry (01-01-2023)“…Leprosy is a Neglected Tropical Disease (NTDs) caused by Mycobacterium leprae (M. leprae). The treatment is considered effective, however, the high dose…”
Get more information
Journal Article -
6
Insight into and Computational Studies of the Selective Synthesis of 6H‑Dibenzo[b,h]xanthenes
Published in Journal of organic chemistry (01-07-2016)“…Starting from 2-hydroxy-1,4-naphthoquinone (lawsone), we synthesized eight new 6H-dibenzo[b,h]xanthene derivatives selectively under solvent-free conditions…”
Get full text
Journal Article -
7
Theoretical and Experimental Spectroscopic Study on 2-Chloro-3-(substitutedphenylamino)-1,4-naphthoquinone Derivatives
Published in Journal of the Brazilian Chemical Society (2023)“…The 1,4-naphthoquinones are an important group of compounds intensively studied because of their wide range of biological activities. Four…”
Get full text
Journal Article -
8
Synthesis, antitubercular activity, and SAR study of N-substituted-phenylamino-5-methyl-1H-1,2,3-triazole-4-carbohydrazides
Published in Bioorganic & medicinal chemistry (15-09-2011)“…This paper describes the synthesis, experimental evaluation for antitubercular activity and theoretical analysis of the…”
Get full text
Journal Article -
9
Nitrogen-Based Heterocyclic Compounds: A Promising Class of Antiviral Agents against Chikungunya Virus
Published in Life (Basel, Switzerland) (30-12-2020)“…Arboviruses, in general, are a global threat due to their morbidity and mortality, which results in an important social and economic impact. Chikungunya virus…”
Get full text
Journal Article -
10
Theoretical Investigation of Regiodivergent Addition of Anilines and Phenolates to p‑Benzoquinone Ring
Published in ACS omega (08-11-2022)“…Two different products were obtained by the regiodivergent reaction of benzoquinone derivatives with phenolates and anilines: 3-aryloxybenzoquinone and…”
Get full text
Journal Article -
11
Synthesis, biological, and theoretical evaluations of new 1,2,3-triazoles against the hemolytic profile of the Lachesis muta snake venom
Published in Bioorganic & medicinal chemistry (01-11-2009)“…This paper describes the synthesis, pharmacological and theoretical evaluation of new 1-arylsulfonylamino-5-methyl-1 H-[1,2,3]-triazole-4-carboxylic acid ethyl…”
Get full text
Journal Article -
12
Exploring 1,2,3-triazole derivatives by using in vitro and in silico assays to target new antifungal agents and treat Candidiasis
Published in Medicinal chemistry research (01-03-2017)“…Candidiasis is a serious public health problem that currently affects not only immunodeficient patients with predisposing conditions, but also immunocompetent…”
Get full text
Journal Article -
13
Efficient access to β - vinylporphyrin derivatives via palladium cross coupling of β-bromoporphyrins with N -tosylhydrazones
Published in Beilstein journal of organic chemistry (30-01-2017)“…This work describes a new approach to obtain new β-vinylporphyrin derivatives through palladium-catalyzed cross-coupling reaction of…”
Get full text
Journal Article -
14
Antivenom Effects of 1,2,3-Triazoles against Bothrops jararaca and Lachesis muta Snakes
Published in BioMed research international (01-01-2013)“…Snake venoms are complex mixtures of proteins of both enzymes and nonenzymes, which are responsible for producing several biological effects. Human…”
Get full text
Journal Article -
15
Synthesis and Biological Evaluation of Benzo[f]indole-4,9-diones N-Linked to Carbohydrate Chains as New Type of Antitumor Agents
Published in Journal of the Brazilian Chemical Society (01-03-2021)“…In this work, we report the synthesis of three series of carbohydrate-based benzo[f]indole-4,9-diones and amino-1,4-naphthoquinone derivatives and evaluated…”
Get full text
Journal Article -
16
Synthesis and in vitro and in silico studies of 1H- and 2H-1,2,3-triazoles as antichagasic agents
Published in Bioorganic chemistry (01-11-2021)“…[Display omitted] •Two series of 5-amino 1H- and 2H-1,2,3-Triazoles were synthesized.•Both series have been evaluated against epimastigote form of Trypanosoma…”
Get full text
Journal Article -
17
Unlocking the Potential of Hydroxycinnamic Acid Bioconjugates: Tailored Derivatives for Biomedical, Cosmetic, and Food Applications
Published in Compounds (10-10-2024)“…This review discusses the development and applications of bioconjugates derived from natural hydroxycinnamic acids (HCA), such as coumaric, sinapic, ferulic,…”
Get full text
Journal Article -
18
Synthesis and antimicrobial evaluation of promising 7-arylamino-5,8-dioxo-5,8-dihydroisoquinoline-4-carboxylates and their halogenated amino compounds for treating Gram-negative bacterial infections
Published in RSC advances (01-01-2017)“…Pathogenic bacteria may cause serious infections, such as pneumonia, which can be fatal especially to immunosuppressed individuals. Hospitalized patients are…”
Get full text
Journal Article -
19
Synthesis and antitumor evaluation of hybrids of 5,8-dioxo-5,8-dihydroisoquinoline-4-carboxylates and carbohydrates
Published in Future medicinal chemistry (01-03-2018)“…Cancer has emerged as a growing public health problem in many parts of the world. We describe the synthesis of a series of carbohydrate-based…”
Get full text
Journal Article -
20
Insight into and Computational Studies of the Selective Synthesis of 6 H -Dibenzo[ b , h ]xanthenes
Published in Journal of organic chemistry (01-07-2016)Get full text
Journal Article