Search Results - "Campos, Raul I."

Considerably Unfolded Transthyretin Monomers Preceed and Exchange with Dynamically Structured Amyloid Protofibrils by Groenning, Minna, Campos, Raul I., Hirschberg, Daniel, Hammarström, Per, Vestergaard, Bente

“…Despite numerous studies, a detailed description of the transthyretin (TTR) self-assembly mechanism and fibril structure in TTR amyloidoses remains unresolved…”
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Thermodynamic stability and denaturation kinetics of a benign natural transthyretin mutant identified in a Danish kindred by Groenning, Minna, Campos, Raul I., Fagerberg, Christina, Rasmussen, Anders Aamann, Eriksen, Ulrik H., Powers, Evan T., Hammarström, Per

“…The disease phenotype of transthyretin (TTR) is dramatically influenced by single point mutations in the TTR gene. Herein, we report on a novel mutation D99N…”
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Novel trans-Stilbene-based Fluorophores as Probes for Spectral Discrimination of Native and Protofibrillar Transthyretin by Campos, Raúl I, Wu, Xiongyu, Elgland, Mathias, Konradsson, Peter, Hammarström, Per

“…Accumulation of misfolded transthyretin (TTR) as amyloid fibrils causes various human disorders. Native transthyretin is a neurotrophic protein and is a…”
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Pathological, biochemical, and biophysical characteristics of the transthyretin variant Y114H (p.Y134H) explain its very mild clinical phenotype by Sekijima, Yoshiki, Campos, Raúl I., Hammarström, Per, Nilsson, K. Peter R., Yoshinaga, Tsuneaki, Nagamatsu, Kiyoshiro, Yazaki, Masahide, Kametani, Fuyuki, Ikeda, Shu‐ichi

“…Transthyretin (TTR) is a homotetrameric protein that must misfold in order to form amyloid fibrils. Misfolding includes rate limiting tetramer dissociation,…”
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