Search Results - "Campos, Debora Leite"
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New Silver(I) Coordination Compound Loaded into Polymeric Nanoparticles as a Strategy to Improve In Vitro Anti-Helicobacter pylori Activity
Published in Molecular pharmaceutics (06-07-2020)“…Helicobacter pylori inhabits the gastric epithelium and can promote the development of gastric disorders, such as peptic ulcers, acute and chronic gastritis,…”
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Screening of novel narrow-spectrum benzofuroxan derivatives for the treatment of multidrug-resistant tuberculosis through in silico , in vitro , and in vivo approaches
Published in Frontiers in microbiology (11-10-2024)“…Tuberculosis remains a serious global health threat, exacerbated by the rise of resistant strains. This study investigates the potential of two benzofuroxan (…”
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Preventive activity of Copaifera langsdorffii Desf. leaves extract and its major compounds, afzelin and quercitrin, on DNA damage in in vitro and in vivo models
Published in Journal of Toxicology and Environmental Health, Part A (18-07-2021)“…Copaifera langsdorffii Desf. is a plant found in South America, especially in Brazil. Oleoresin and the leaves of this plant is used as a popular medicinal…”
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Latent Tuberculosis: A Promising New Compound to Treat Non-Replicating and Intramacrophagic Mycobacteria
Published in Biomedicines (26-09-2022)“…As a biologic reservoir of Mycobacterium tuberculosis (M. tb), one-quarter of the world population is infected with the well-known latent tuberculosis (LTBI)…”
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Liposome-siderophore conjugates loaded with moxifloxacin serve as a model for drug delivery against Mycobacterium tuberculosis
Published in International journal of pharmaceutics (25-04-2024)“…[Display omitted] Tuberculosis (TB) is an infectious disease that annually affects millions of people, and resistance to available antibiotics has exacerbated…”
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Study of antimycobacterial, cytotoxic, and mutagenic potential of polymeric nanoparticles of copper (II) complex
Published in Journal of microencapsulation (02-01-2022)“…This study aimed to encapsulate and characterise a potential anti-tuberculosis copper complex (CuCl 2 (INH) 2 .H 2 O:I1) into polymeric nanoparticles (PNs) of…”
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Growth-inhibitory effects of tris-(1,10-phenanthroline) iron (II) against Mycobacterium tuberculosis in vitro and in vivo
Published in Tuberculosis (Edinburgh, Scotland) (01-05-2021)“…Mycobacterium tuberculosis is the major etiological agent for tuberculosis (TB), which is the leading cause of single pathogen infection-related deaths…”
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New antimycobacterial agents in the pre-clinical phase or beyond: recent advances in patent literature (2001-2016)
Published in Expert opinion on therapeutic patents (04-03-2017)“…Tuberculosis, an infectious disease, has caused more deaths worldwide than any other single infectious disease, killing more than 1.5 million people each year;…”
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Antigenotoxicity properties of Copaifera multijuga oleoresin and its chemical marker, the diterpene (−)-copalic acid
Published in Journal of Toxicology and Environmental Health, Part A (01-01-2018)“…In view of the biological activities and growing therapeutic interest in oleoresin obtained from Copaifera multijuga, this study aimed to determine the…”
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Mutagenicity and chemopreventive activities of Astronium species assessed by Ames test
Published in Regulatory toxicology and pharmacology (01-08-2015)“…•Astronium spp. has been investigated for medicinal activity.•None of the extracts showed mutagenic activity.•The protective effects were evaluated against…”
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