Search Results - "Campi, Gabriele"

Altered TCR Signaling from Geometrically Repatterned Immunological Synapses by Mossman, Kaspar D, Campi, Gabriele, Groves, Jay T, Dustin, Michael L

“…The immunological synapse is a specialized cell-cell junction that is defined by large-scale spatial patterns of receptors and signaling molecules yet remains…”
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The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2 by Zheng, Yang, Campi, Gabriele, Dustin, Michael L, Du, Guangwei, Mor, Adam, Philips, Mark R, Foster, David A

“…Ras activation as a consequence of antigen receptor (T-cell receptor; TCR) engagement on T lymphocytes is required for T-cell development, selection and…”
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An efficient strategy to induce and maintain in vitro human T cells specific for autologous non-small cell lung carcinoma by Canderan, Glenda, Gruarin, Paola, Montagna, Daniela, Fontana, Raffaella, Campi, Gabriele, Melloni, Giulio, Traversari, Catia, Dellabona, Paolo, Casorati, Giulia

“…The efficient expansion in vitro of cytolytic CD8+ T cells (CTLs) specific for autologous tumors is crucial both for basic and translational aspects of tumor…”
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T Cell Receptor-Proximal Signals Are Sustained in Peripheral Microclusters and Terminated in the Central Supramolecular Activation Cluster by Varma, Rajat, Campi, Gabriele, Yokosuka, Tadashi, Saito, Takashi, Dustin, Michael L.

“…T cell receptor (TCR) signaling is initiated and sustained in microclusters; however, it's not known whether signaling also occurs in the TCR-rich central…”
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Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling by Campi, Gabriele, Varma, Rajat, Dustin, Michael L

“…T cell receptor (TCR) microclusters form within seconds of T cell contact with supported planar bilayers containing intercellular adhesion molecule-1 and…”
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T cell–dendritic cell immunological synapses by Dustin, Michael L, Tseng, Su-Yi, Varma, Rajat, Campi, Gabriele

“…Dendritic cells (DCs) are myeloid lineage cells that are imprinted by their environment and that mature in response to microbial products. A crucial role of…”
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The Immunological Synapse Balances T Cell Receptor Signaling and Degradation by Lee, Kyeong-Hee, Dinner, Aaron R., Tu, Chun, Campi, Gabriele, Raychaudhuri, Subhadip, Varma, Rajat, Sims, Tasha N., Burack, W. Richard, Wu, Hui, Wang, Julia, Kanagawa, Osami, Markiewicz, Mary, Allen, Paul M., Dustin, Michael L., Chakraborty, Arup K., Shaw, Andrey S.

“…The immunological synapse is a specialized cell-cell junction between T cell and antigen-presenting cell surfaces. It is characterized by a central cluster of…”
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Correction: An Efficient Strategy to Induce and Maintain In Vitro Human T Cells Specific for Autologous Non-Small Cell Lung Carcinoma by Canderan, Glenda, Gruarin, Paola, Montagna, Daniela, Fontana, Raffaella, Campi, Gabriele, Melloni, Giulio, Traversari, Catia, Dellabona, Paolo, Casorati, Giulia

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Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling by Campi, Gabriele, Varma, Rajat, Dustin, Michael L

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CD4+ T cells from healthy subjects and colon cancer patients recognize a carcinoembryonic antigen-specific immunodominant epitope by CAMPI, Gabriele, CROSTI, Mariacristina, CONSOGNO, Giuseppe, FACCHINETTI, Valeria, CONTI-FINE, Bianca M, LONGHI, Renato, CASORATI, Giulia, DELLABONA, Paolo, PROTTI, Maria Pia

“…The carcinoembryonic antigen (CEA) is an attractive target for immunotherapeutic purposes because of its expression profile, its role in tumor progression, and…”
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A new Chinese hamster ovary cell line expressing α2,6-sialyltransferase used as universal host for the production of human-like sialylated recombinant glycoproteins by Bragonzi, Alessandra, Distefano, Gianfranco, Buckberry, Lorraine D, Acerbis, Giulia, Foglieni, Chiara, Lamotte, Damien, Campi, Gabriele, Marc, Annie, Soria, Marco R, Jenkins, Nigel, Monaco, Lucia

“…Chinese hamster ovary (CHO) cells are widely employed to produce glycosylated recombinant proteins. Our group as well as others have demonstrated that the…”
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Peripheral signaling in the immunological synapse: Role of TCR micro-clusters by Campi, Gabriele

“…The immunological synapse (IS) is a multi-molecular structure that forms at contact sites between T cells and Antigen Presenting Cells (APC). As far as T cell…”
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Correction: An Efficient Strategy to Induce and Maintain Human T Cells Specific for Autologous Non-Small Cell Lung Carcinoma by Glenda Canderan, Paola Gruarin, Daniela Montagna, Raffaella Fontana, Gabriele Campi, Giulio Melloni, Catia Traversari, Paolo Dellabona, Giulia Casorati

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Initiation of antiretroviral therapy during primary HIV-1 infection induces rapid stabilization of the T-cell receptor β chain repertoire and reduces the level of T-cell oligoclonality by Soudeyns, Hugo, Campi, Gabriele, Rizzardi, G. Paolo, Lenge, Caterina, Demarest, James F., Tambussi, Giuseppe, Lazzarin, Adriano, Kaufmann, Daniel, Casorati, Giulia, Corey, Lawrence, Pantaleo, Giuseppe

“…Major T-cell receptor β chain variable region (TCRBV) repertoire perturbations are temporally associated with the down-regulation of viremia during primary…”
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