Search Results - "Camphausen, R T"

Core2 β-1,6-N-Acetylglucosaminyltransferase Enzyme Activity Is Critical for P-Selectin Glycoprotein Ligand-1 Binding to P-Selectin by Kumar, Ravindra, Camphausen, Raymond T., Sullivan, Francis X., Cumming, Dale A.

“…P-selectin glycoprotein ligand-1 (PSGL-1) is a high-affinity counterreceptor for P-selectin on myeloid cells and activated T-cells. In addition, PSGL-1 can…”
Get full text

Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1 by Somers, W S, Tang, J, Shaw, G D, Camphausen, R T

“…P-, E- and L-selectin constitute a family of cell adhesion receptors that mediate the initial tethering and rolling of leukocytes on inflamed endothelium as a…”
Get full text

A human colon carcinoma cell line exhibits adhesive interactions with P- selectin under fluid flow via a PSGL-1-independent mechanism by Goetz, DJ, Ding, H, Atkinson, WJ, Vachino, G, Camphausen, RT, Cumming, DA, Luscinskas, FW

“…It has been postulated that endothelial cell adhesion molecules involved in leukocyte recruitment play a role in metastasis. Using an in vitro flow model, we…”
Get full text

The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis by Malý, Petr, Thall, Aron D, Petryniak, Bronislawa, Rogers, Clare E, Smith, Peter L, Marks, Rory M, Kelly, Robert J, Gersten, Kevin M, Cheng, Guiying, Saunders, Thomas L, Camper, Sally A, Camphausen, Ray T, Sullivan, Francis X, Isogai, Yukihiro, Hindsgaul, Ole, von Andrian, Ulrich H, Lowe, John B

“…α(1,3)Fucosylated oligosaccharides represent components of leukocyte counterreceptors for E- and P-selectins and of L-selectin ligands expressed by lymph node…”
Get full text

A sulfated peptide segment at the amino terminus of PSGL-1 is critical for P-selectin binding by Sako, Dianne, Comess, Kenneth M., Barone, Karen M., Camphausen, Raymond T., Cumming, Dale A., Shaw, Gray D.

“…P-selectin glycoprotein ligand 1 (PSGL-1) is a mucin-like glycoprotein expressed on the surface of myeloid cells and serves as the high affinity…”
Get full text

Sialyl Lewis(x)-mediated, PSGL-1-independent rolling adhesion on P-selectin by Rodgers, S D, Camphausen, R T, Hammer, D A

“…Selectin-mediated cell adhesion is an essential component of the inflammatory response. In an attempt to unambiguously identify molecular features of ligands…”
Get full text

Implications of antibodies to pyruvylated glucose in healthy populations for mycobacterioses and other infectious diseases by THAYER, W. R, BOZIC, C. M, CAMPHAUSEN, R. T, MCNEIL, M

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

A Glycolipid Antigen Specific to Mycobacterium paratuberculosis: Structure and Antigenicity by Camphausen, Raymond T., Jones, Robert L., Brennan, Patrick J.

“…Mycobacterium paratuberculosis (National Animal Disease Center strain 18 and American Type Culture Collection strain 19698), the causative agent of Johne…”
Get full text

Location of acyl groups of trehalose-containing lipooligosaccharides of mycobacteria by CAMPHAUSEN, R. T, MCNEIL, M, JARDINE, I, BRENNAN, P. J

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Structure and relevance of the oligosaccharide hapten of Mycobacterium avium serotype 2 by Camphausen, R.T, Jones, R.L, Brennan, P.J

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Isolated P-Selectin Glycoprotein Ligand-1 Dynamic Adhesion to P- and E-Selectin by Goetz, Douglas J., Greif, Daniel M., Ding, Han, Camphausen, Raymond T., Howes, Steven, Comess, Kenneth M., Snapp, Karen R., Kansas, Geoffrey S., Luscinskas, Francis W.

“…Leukocyte adhesion to vascular endothelium under flow involves an adhesion cascade consisting of multiple receptor pairs that may function in an overlapping…”
Get full text

Neutrophils, Monocytes, and Dendritic Cells Express the Same Specialized Form of PSGL-1 as Do Skin-Homing Memory T Cells: Cutaneous Lymphocyte Antigen by Kieffer, J.David, Fuhlbrigge, Robert C., Armerding, Dieter, Robert, Caroline, Ferenczi, Katalin, Camphausen, Raymond T., Kupper, Thomas S.

“…Memory T cells in inflamed skin express the cutaneous lymphocyte-associated antigen (CLA), a glycosylated epitope defined by the mAb HECA-452. We previously…”
Get full text

Antigenic relationship between Mycobacterium paratuberculosis and Mycobacterium avium by Camphausen, R T, Jones, R L, Brennan, P J

“…Four prototype strains of Mycobacterium paratuberculosis contained the type-specific glycopeptidolipid antigen of serovar 8 of the M avium complex. This…”
Get more information

Design and synthesis of sialyl Lewis x mimics as E-selectin inhibitors by KAILA, Neelu, THOMAS, Bert E, THAKKER, Paresh, ALVAREZ, Juan C, CAMPHAUSEN, Raymond T, CROMMIE, Deidre

“…The design and synthesis of novel beta-C-mannosides that inhibit the binding of sialyl Lewis x to E-selectin are described. Compounds that contained a phenyl…”
Get full text

Rolling Adhesion Kinematics of Yeast Engineered To Express Selectins by Bhatia, Sujata K., Swers, Jeffrey S., Camphausen, Raymond T., Wittrup, K. Dane, Hammer, Daniel A.

“…Selectins are cell adhesion molecules that mediate capture of leukocytes on vascular endothelium as an essential component of the inflammatory response. Here…”
Get full text

Identification and structural determination of a potent p-selectin inhibitor by Kaila, Neelu, Xu, Guang-Yi, Camphausen, Raymond T., Xiang, YiBin

“…Small quantities of a potent P-selectin inhibitor, 2 (IC 50=0.2 μM), were isolated and an initial structure proposed based on 1D proton NMR. A reterosynthetic…”
Get full text

Synthesis and Biological Evaluation of Quinoline Salicylic Acids As P-Selectin Antagonists by Kaila, Neelu, Janz, Kristin, DeBernardo, Silvano, Bedard, Patricia W, Camphausen, Raymond T, Tam, Steve, Tsao, Desirée H. H, Keith, James C, Nickerson-Nutter, Cheryl, Shilling, Adam, Young-Sciame, Ruth, Wang, Qin

“…Leukocyte recruitment of sites of inflammation and tissue injury involves leukocyte rolling along the endothelial wall, followed by firm adherence of the…”
Get full text

Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A by Wagner, Denisa D, Hrachovinová, Ingrid, Cambien, Beatrice, Hafezi-Moghadam, Ali, Kappelmayer, János, Camphausen, Raymond T, Widom, Angela, Xia, Lijun, Kazazian, Haig H, Schaub, Robert G, McEver, Rodger P

“…High plasma levels of soluble P-selectin are associated with thrombotic disorders and may predict future cardiovascular events. Mice with high levels of…”
Get full text

Tyrosine Sulfation Enhances but Is Not Required for PSGL-1 Rolling Adhesion on P-Selectin by Rodgers, Stephen D., Camphausen, Raymond T., Hammer, Daniel A.

“…P-selectin glycoprotein ligand-1 (PSGL-1) is a large (240 kDa) glycoprotein found on the surface of nearly all leukocytes. The mature molecule is decorated…”
Get full text

Insights into the Molecular Basis of Leukocyte Tethering and Rolling Revealed by Structures of P- and E-Selectin Bound to SLe super(x) and PSGL-1 by Somers, W S, Tang, Jin, Shaw, G D, Camphausen, R T

“…P-, E- and L-selectin constitute a family of cell adhesion receptors that mediate the initial tethering and rolling of leukocytes on inflamed endothelium as a…”
Get full text