Search Results - "Campbell, Scott A."

Human islets contain a subpopulation of glucagon-like peptide-1 secreting α cells that is increased in type 2 diabetes by Campbell, Scott A., Golec, Dominic P., Hubert, Matt, Johnson, Janyne, Salamon, Nicole, Barr, Amy, MacDonald, Patrick E., Philippaert, Koenraad, Light, Peter E.

“…Our study shows that glucagon-like peptide-1 (GLP-1) is secreted within human islets and may play an unexpectedly important paracrine role in islet physiology…”
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Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice by Croze, Marine L., Flisher, Marcus F., Guillaume, Arthur, Tremblay, Caroline, Noguchi, Glyn M., Granziera, Sabrina, Vivot, Kevin, Castillo, Vincent C., Campbell, Scott A., Ghislain, Julien, Huising, Mark O., Poitout, Vincent

“…Maintenance of glucose homeostasis requires the precise regulation of hormone secretion from the endocrine pancreas. Free fatty acid receptor 4 (FFAR4/GPR120)…”
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14-3-3ζ Constrains insulin secretion by regulating mitochondrial function in pancreatic β cells by Mugabo, Yves, Zhao, Cheng, Tan, Ju Jing, Ghosh, Anindya, Campbell, Scott A, Fadzeyeva, Evgenia, Paré, Frédéric, Pan, Siew Siew, Galipeau, Maria, Ast, Julia, Broichhagen, Johannes, Hodson, David J, Mulvihill, Erin E, Petropoulos, Sophie, Lim, Gareth E

“…While critical for neurotransmitter synthesis, 14-3-3 proteins are often assumed to have redundant functions due to their ubiquitous expression, but despite…”
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Vitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel by Long, Wentong, Fatehi, Mohammad, Soni, Shubham, Panigrahi, Rashmi, Philippaert, Koenraad, Yu, Yi, Kelly, Rees, Boonen, Brett, Barr, Amy, Golec, Dominic, Campbell, Scott A., Ondrusova, Katarina, Hubert, Matt, Baldwin, Troy, Lemieux, M. Joanne, Light, Peter E.

“…Key points 25‐Hydroxyvitamin D (25OHD) is a partial agonist of TRPV1 whereby 25OHD can weakly activate TRPV1 yet antagonize the stimulatory effects of the full…”
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Combined Deletion of Free Fatty-Acid Receptors 1 and 4 Minimally Impacts Glucose Homeostasis in Mice by Croze, Marine L, Guillaume, Arthur, Ethier, Mélanie, Fergusson, Grace, Tremblay, Caroline, Campbell, Scott A, Maachi, Hasna, Ghislain, Julien, Poitout, Vincent

“…The free fatty-acid receptors FFAR1 (GPR40) and FFAR4 (GPR120) are implicated in the regulation of insulin secretion and insulin sensitivity, respectively…”
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Evidence for the existence and potential roles of intra-islet glucagon-like peptide-1 by Campbell, Scott A., Johnson, Janyne, Light, Peter E.

“…Glucagon-Like Peptide-1 (GLP-1) is an important peptide hormone secreted by L-cells in the gastrointestinal tract in response to nutrients. It is produced by…”
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The Tetracycline-Controlled Transactivator (Tet-On/Off) System in β-Cells Reduces Insulin Expression and Secretion in Mice by Jouvet, Nathalie, Bouyakdan, Khalil, Campbell, Scott A, Baldwin, Cindy, Townsend, Shannon E, Gannon, Maureen A, Poitout, Vincent, Alquier, Thierry, Estall, Jennifer L

“…Controllable genetic manipulation is an indispensable tool in research, greatly advancing our understanding of cell biology and physiology. However in β-cells,…”
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256-OR: Costarting Sitagliptin with Metformin Is Associated with a Lower Likelihood of Disease Progression in Newly Treated Patients with Type 2 Diabetes by CAMPBELL, SCOTT A., LIGHT, PETER E., SIMPSON, SCOT H.

“…Aim: Sitagliptin can potentially preserve beta cell function by promoting local action of GLP-1 in the pancreas. This study examined if early addition of…”
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Clinical Utility of Reflex Testing with Cancer Biomarkers to Improve Diagnostic Accuracy of Primary Human Papillomavirus Screening by Johnson, Lauren G, Saidu, Rakiya, Svanholm-Barrie, Cecilia, Boa, Rosalind, Moodley, Jennifer, Tergas, Ana, Persing, David, Campbell, Scott A, Tsai, Wei-Yann, Wright, Thomas C, Denny, Lynette, Kuhn, Louise

“…Human papillomavirus (HPV) testing is the cornerstone of cervical cancer screening, with outstanding sensitivity but only moderate specificity. We evaluated…”
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Prospective Validation of an mRNA-based Urine Test for Surveillance of Patients with Bladder Cancer by Valenberg, F. Johannes P. van, Hiar, Andrew M., Wallace, Ellen, Bridge, Julia A., Mayne, Donna J., Beqaj, Safedin, Sexton, Wade J., Lotan, Yair, Weizer, Alon Z., Jansz, Godfrey K., Stenzl, Arnulf, Danella, John F., Shepard, Barry, Cline, Kevin J., Williams, Michael B., Montgomery, Scott, David, Richard D., Harris, Richard, Klein, Eric W., Bradford, Timothy J., Wolk, Fred N., Westenfelder, Karl R., Trainer, Andrew F., Richardson, Timothy A., Egerdie, Russell B., Goldfarb, Bernard, Zadra, Joseph A., Ge, Sijian, Zhao, Suling, Simon, Iris M., Campbell, Scott A., Rhees, Brian, Bates, Michael P., Higuchi, Russell G., Witjes, J. Alfred

“…A fast, noninvasive test with high sensitivity (SN) and a negative predictive value (NPV), which is able to detect recurrences in bladder cancer (BC) patients,…”
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Very-Long-Chain Unsaturated Sphingolipids Mediate Oleate-Induced Rat β-Cell Proliferation by Castell, Anne-Laure, Vivoli, Alexis, Tippetts, Trevor S, Frayne, Isabelle Robillard, Angeles, Zuraya Elisa, Moullé, Valentine S, Campbell, Scott A, Ruiz, Matthieu, Ghislain, Julien, Des Rosiers, Christine, Holland, William L, Summers, Scott A, Poitout, Vincent

“…Fatty acid (FA) signaling contributes to β-cell mass expansion in response to nutrient excess, but the underlying mechanisms are poorly understood. In the…”
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258-LB: Vitamin D Directly Regulates TRPV1 Channel Activity and May Play an Important Role in the Autoimmune Disease of Type 1 Diabetes by LONG, WENTONG, FATEHI, MOHAMMAD, SONI, SHUBHAM, PANIGRAHI, RASHMI, KELLY, REES G., PHILIPPAERT, KOENRAAD, BARR, AMY J., HELD, MORGANNE, YU, YI, CAMPBELL, SCOTT A., ONDRUSOVA, KATARINA, BALDWIN, TROY, LEMIEUX, JOANNE, LIGHT, PETER E.

“…The autoimmune disease of type 1 diabetes (T1D) results in the immune destruction of β-cells. Recent studies suggest supplementation of vitamin D along can…”
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Validation of an mRNA-based Urine Test for the Detection of Bladder Cancer in Patients with Haematuria by Valenberg, Franciscus Johannes P. van, Hiar, Andrew M., Wallace, Ellen, Bridge, Julia A., Mayne, Donna J., Beqaj, Safedin, Sexton, Wade J., Lotan, Yair, Weizer, Alon Z., Jansz, Godfrey K., Stenzl, Arnulf, Danella, John F., Cline, Kevin J., Williams, Michael B., Montgomery, Scott, David, Richard D., Harris, Richard, Klein, Eric W., Bradford, Timothy J., Wolk, Fred N., Westenfelder, Karl R., Trainer, Andrew F., Richardson, Timothy A., Egerdie, Russell B., Goldfarb, Bernard, Zadra, Joseph A., Lu, Xixi, Simon, Iris M., Campbell, Scott A., Bates, Michael P., Higuchi, Russell G., Witjes, J. Alfred

“…In patients with haematuria, a fast, noninvasive test with high sensitivity (SN) and negative predictive value (NPV), which is able to detect or exclude…”
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The antianginal ranolazine mitigates obesity-induced nonalcoholic fatty liver disease and increases hepatic pyruvate dehydrogenase activity by Al Batran, Rami, Gopal, Keshav, Aburasayn, Hanin, Eshreif, Amina, Almutairi, Malak, Greenwell, Amanda A, Campbell, Scott A, Saleme, Bruno, Court, Emily A, Eaton, Farah, Light, Peter E, Sutendra, Gopinath, Ussher, John R

“…Obese individuals are often at risk for nonalcoholic fatty liver disease (NAFLD), insulin resistance, type 2 diabetes (T2D), and cardiovascular diseases such…”
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Perceived Barriers to Hepatitis C Therapy for Patients Receiving Opioid Agonist Treatment by Zickmund, Susan L, Campbell, Scott A, Tirado, Carlos F, Zook, Carolyn L, Weinrieb, Robert M

“…OBJECTIVES:To explore attitudes toward hepatitis C antiviral therapy in a real-world setting, we asked patients in opioid agonist treatment who were offered…”
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CHARACTERIZING POTENTIAL EXPOSURE TO THE PUBLIC FROM LOW-LEVEL RADIOACTIVE WASTE TRANSPORTATION BY TRUCK by Miller, Julianne J, Shafer, David S, Gray, Karen J, Church, Bruce W, Tappen, Jeffrey J, Campbell, Scott A, Holz, Barbara A

“…To address public concern about potential exposure to gamma radiation from legal-weight low-level radioactive waste truck shipments to the Nevada Test Site, a…”
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13 - RGS9 Is Required for Glucose-Induced Beta-Cell Proliferation in Ex Vivo Pancreatic Islets by Campbell, Scott A., Szpigel, Anais, Tremblay, Caroline, Ghislain, Julien, Poitout, Vincent

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A ca. 40 kDa maize (Zea mays L.) embryo dehydrin is encoded by the dhn2 locus on chromosome 9 by Campbell, S.A. (California Univ., Riverside, CA (USA). Dept. of Botany and Plant Sciences), Crone, D.E, Ceccardi, T.L, Close, T.J

“…Dehydrins (LEA D11 proteins) are the products of multigene families in a number of higher plants. To date, however, only one dehydrin locus, dhn1 (a major…”
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Combined Deletion of Free Fatty-Acid Receptors 1 and 4 Minimally Impacts Glucose Homeostasis in Mice by Croze, Marine L, Guillaume, Arthur, Ethier, Mélanie, Fergusson, Grace, Tremblay, Caroline, Campbell, Scott A, Maachi, Hasna, Ghislain, Julien, Poitout, Vincent

“…The free fatty-acid receptors FFAR1 (GPR40) and FFAR4 (GPR120) are implicated in the regulation of insulin secretion and insulin sensitivity, respectively…”
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Dehydrins: genes, proteins, and associations with phenotypic traits by CAMPBELL, SCOTT A., CLOSE, TIMOTHY J.

“…Dehydrin proteins (late embryogenesis abundant (LEA) D11 family) are produced in a wide variety of plant species in response to environmental stimuli with a…”
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