Search Results - "Campbell, Meghan"

Locked vs. unlocked nucleic acids (LNA vs. UNA): contrasting structures work towards common therapeutic goals by Campbell, Meghan A, Wengel, Jesper

“…Oligonucleotide chemistry has been developed greatly over the past three decades, with many advances in increasing nuclease resistance, enhancing duplex…”
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USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-Dependent Protein Levels by Kerrisk Campbell, Meghan, Sheng, Morgan

“…Mutations or altered protein levels of SHANK3 are implicated in neurodevelopmental disorders such as Phelan-McDermid syndrome, autism spectrum disorders, and…”
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Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson’s disease by Liu, Ganqiang, Peng, Jiajie, Liao, Zhixiang, Locascio, Joseph J., Corvol, Jean-Christophe, Zhu, Frank, Dong, Xianjun, Maple-Grødem, Jodi, Campbell, Meghan C., Elbaz, Alexis, Lesage, Suzanne, Brice, Alexis, Mangone, Graziella, Growdon, John H., Hung, Albert Y., Schwarzschild, Michael A., Hayes, Michael T., Wills, Anne-Marie, Herrington, Todd M., Ravina, Bernard, Shoulson, Ira, Taba, Pille, Kõks, Sulev, Beach, Thomas G., Cormier-Dequaire, Florence, Alves, Guido, Tysnes, Ole-Bjørn, Perlmutter, Joel S., Heutink, Peter, Amr, Sami S., van Hilten, Jacobus J., Kasten, Meike, Mollenhauer, Brit, Trenkwalder, Claudia, Klein, Christine, Barker, Roger A., Williams-Gray, Caroline H., Marinus, Johan, Scherzer, Clemens R.

“…A key driver of patients’ well-being and clinical trials for Parkinson’s disease (PD) is the course that the disease takes over time (progression and…”
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PCDH7 interacts with GluN1 and regulates dendritic spine morphology and synaptic function by Wang, Yuanyuan, Kerrisk Campbell, Meghan, Tom, Irene, Foreman, Oded, Hanson, Jesse E., Sheng, Morgan

“…The N-terminal domain (NTD) of the GluN1 subunit (GluN1-NTD) is important for NMDA receptor structure and function, but the interacting proteins of the…”
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CEDAW and Women’s Intersecting Identities: A Pioneering New Approach to Intersectional Discrimination by Campbell, Meghan

“…ABSTRACT CEDAW is committed to eliminating all forms of discrimination and achieving gender equality so that all women can exercise and enjoy their human…”
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Correlation between decreased CSF α-synuclein and Aβ1–42 in Parkinson disease by Buddhala, Chandana, Campbell, Meghan C, Perlmutter, Joel S, Kotzbauer, Paul T

“…Abstract Accumulation of misfolded α-synuclein (α-syn) protein in Lewy bodies and neurites is the cardinal pathologic feature of Parkinson disease (PD), but…”
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The View from the Back Row by Campbell, Meghan A.

“…Taking it all in: Exploring the role of editors at conferences will help you understand how to make the most of such an interaction. After wrapping up a…”
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Cognitive correlates of cerebellar resting-state functional connectivity in Parkinson disease by Maiti, Baijayanta, Koller, Jonathan M., Snyder, Abraham Z., Tanenbaum, Aaron B., Norris, Scott A., Campbell, Meghan C., Perlmutter, Joel S.

“…OBJECTIVETo investigate in a cross-sectional study the contributions of altered cerebellar resting-state functional connectivity (FC) to cognitive impairment…”
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Removal of high frequency contamination from motion estimates in single-band fMRI saves data without biasing functional connectivity by Gratton, Caterina, Dworetsky, Ally, Coalson, Rebecca S., Adeyemo, Babatunde, Laumann, Timothy O., Wig, Gagan S., Kong, Tania S., Gratton, Gabriele, Fabiani, Monica, Barch, Deanna M., Tranel, Daniel, Miranda-Dominguez, Oscar, Fair, Damien A., Dosenbach, Nico U.F., Snyder, Abraham Z., Perlmutter, Joel S., Petersen, Steven E., Campbell, Meghan C.

“…Denoising fMRI data requires assessment of frame-to-frame head motion and removal of the biases motion introduces. This is usually done through analysis of the…”
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Functional anatomy of subthalamic nucleus stimulation in Parkinson disease by Eisenstein, Sarah A., Koller, Jonathan M., Black, Kathleen D., Campbell, Meghan C., Lugar, Heather M., Ushe, Mwiza, Tabbal, Samer D., Karimi, Morvarid, Hershey, Tamara, Perlmutter, Joel S., Black, Kevin J.

“…Objective We developed a novel method to map behavioral effects of deep brain stimulation (DBS) across a 3‐dimensional brain region and to assign statistical…”
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Emergent Functional Network Effects in Parkinson Disease by Gratton, Caterina, Koller, Jonathan M, Shannon, William, Greene, Deanna J, Maiti, Baijayanta, Snyder, Abraham Z, Petersen, Steven E, Perlmutter, Joel S, Campbell, Meghan C

“…Abstract The hallmark pathology underlying Parkinson disease (PD) is progressive synucleinopathy, beginning in caudal brainstem that later spreads rostrally…”
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Proteinopathy and longitudinal changes in functional connectivity networks in Parkinson disease by Campbell, Meghan C., Jackson, Joshua J., Koller, Jonathan M., Snyder, Abraham Z., Kotzbauer, Paul T., Perlmutter, Joel S.

“…OBJECTIVETo evaluate resting-state functional connectivity as a potential prognostic biomarker of Parkinson disease (PD) progression. The study examined…”
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At the Speed of Color by Campbell, Meghan A.

“…Tied up with a (rain)bow: Looking ahead to 2016, important changes are underway at ChemBioChem. The elimination of color charges and accelerated publication…”
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Resting‐State Functional Connectivity Predicts STN DBS Clinical Response by Younce, John R., Campbell, Meghan C., Hershey, Tamara, Tanenbaum, Aaron B., Milchenko, Mikhail, Ushe, Mwiza, Karimi, Morvarid, Tabbal, Samer D., Kim, Albert E., Snyder, Abraham Z., Perlmutter, Joel S., Norris, Scott A.

“…ABSTRACT Background Deep brain stimulation of the subthalamic nucleus is a widely used adjunctive therapy for motor symptoms of Parkinson's disease, but with…”
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Hospital admissions during Covid-19 lock-down in Germany: Differences in discretionary and unavoidable cardiovascular events by Stöhr, Elisabeth, Aksoy, Adem, Campbell, Meghan, Al Zaidi, Muntadher, Öztürk, Can, Vorloeper, Julia, Lange, Jonas, Sugiura, Atsushi, Wilde, Nihal, Becher, Marc Ulrich, Diepenseifen, Christian, Heister, Ulrich, Nickenig, Georg, Zimmer, Sebastian, Tiyerili, Vedat

“…A decline in hospitalization for cardiovascular events and catheter laboratory activation was reported for the United States and Italy during the initial stage…”
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Neocortical Lewy Body Pathology Parallels Parkinson's Dementia, but Not Always by Martin, W. R. Wayne, Younce, John R., Campbell, Meghan C., Racette, Brad A., Norris, Scott A., Ushe, Mwiza, Criswell, Susan, Davis, Albert A., Alfradique‐Dunham, Isabel, Maiti, Baijayanta, Cairns, Nigel J., Perrin, Richard J., Kotzbauer, Paul T., Perlmutter, Joel S.

“…Objective The objective of this study was to evaluate the relationship between Parkinson's disease (PD) with dementia and cortical proteinopathies in a large…”
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CNS Neurons Deposit Laminin α5 to Stabilize Synapses by Omar, Mitchell H., Kerrisk Campbell, Meghan, Xiao, Xiao, Zhong, Qiaonan, Brunken, William J., Miner, Jeffrey H., Greer, Charles A., Koleske, Anthony J.

“…Synapses in the developing brain are structurally dynamic but become stable by early adulthood. We demonstrate here that an α5-subunit-containing laminin…”
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Efficient Chemoenzymatic Synthesis of α‑Aryl Aldehydes as Intermediates in C–C Bond Forming Biocatalytic Cascades by Meza, Anthony, Campbell, Meghan E., Zmich, Anna, Thein, Sierra A., Grieger, Abbigail M., McGill, Matthew J., Willoughby, Patrick H., Buller, Andrew R.

“…Multi-enzyme biocatalytic cascades are emerging as practical routes for the synthesis of complex bioactive molecules. However, the relative sparsity of…”
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Neuroimaging Analysis of the Dopamine Basis for Apathetic Behaviors in an MPTP-Lesioned Primate Model by Tian, LinLin, Xia, Yuanxuan, Flores, Hubert P, Campbell, Meghan C, Moerlein, Stephen M, Perlmutter, Joel S

“…Apathy commonly occurs in Parkinson disease (PD) patients; however, the role of dopamine in the pathophysiology of apathy remains elusive. We previously…”
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Regional, not global, functional connectivity contributes to isolated focal dystonia by Norris, Scott A., Morris, Aimee E., Campbell, Meghan C., Karimi, Morvarid, Adeyemo, Babatunde, Paniello, Randal C., Snyder, Abraham Z., Petersen, Steven E., Mink, Jonathan W., Perlmutter, Joel S.

“…OBJECTIVETo test the hypothesis that there is shared regional or global functional connectivity dysfunction in a large cohort of patients with isolated focal…”
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