Search Results - "Campbell, Leigh"
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Heterogeneous Cadherin Expression and Multicellular Aggregate Dynamics in Ovarian Cancer Dissemination
Published in Neoplasia (New York, N.Y.) (01-07-2017)“…Abstract Epithelial ovarian carcinoma spreads via shedding of cells and multicellular aggregates (MCAs) from the primary tumor into peritoneal cavity, with…”
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Lysophosphatidic acid modulates ovarian cancer multicellular aggregate assembly and metastatic dissemination
Published in Scientific reports (02-07-2020)“…Epithelial ovarian cancer (EOC) metastasis occurs by exfoliation of cells and multicellular aggregates (MCAs) from the tumor into the peritoneal cavity,…”
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In vivo selection of highly metastatic human ovarian cancer sublines reveals role for AMIGO2 in intra-peritoneal metastatic regulation
Published in Cancer letters (10-04-2021)“…The majority of women with ovarian cancer are diagnosed with metastatic disease, therefore elucidating molecular events that contribute to successful…”
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Host obesity alters the ovarian tumor immune microenvironment and impacts response to standard of care chemotherapy
Published in Journal of experimental & clinical cancer research (12-07-2023)“…The majority of women with epithelial ovarian cancer (OvCa) are diagnosed with metastatic disease, resulting in a poor 5-year survival of 31%. Obesity is a…”
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The impact of saliva collection and processing methods on CRP, IgE, and Myoglobin immunoassays
Published in Clinical and translational medicine (05-09-2012)“…Background Owing to its ease of collection, saliva is potentially the sample of choice in diagnosis. Salivary biomolecules have provided a porthole in…”
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Development and validation of prognostic gene signature for basal-like breast cancer and high-grade serous ovarian cancer
Published in Breast cancer research and treatment (01-12-2020)“…Purpose Molecular similarities have been reported between basal-like breast cancer (BLBC) and high-grade serous ovarian cancer (HGSOC). To date, there have…”
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Modeling the effect of ascites-induced compression on ovarian cancer multicellular aggregates
Published in Disease models & mechanisms (01-09-2018)“…Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy. EOC dissemination is predominantly via direct extension of cells and multicellular…”
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Collodion-like membrane in a newborn exposed to infliximab
Published in Journal of the American Academy of Dermatology (01-07-2014)Get full text
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Intracerebral lipopolysaccharide induces neuroinflammatory change and augmented brain injury in growth-restricted neonatal rats
Published in Pediatric research (01-06-2012)“…Introduction: Intrauterine growth restriction (IUGR) alters fetal development and is associated with neurodevelopmental abnormalities. We hypothesized that…”
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IGF-1 Can Either Protect Against or Increase LPS-Induced Damage in the Developing Rat Brain
Published in Pediatric research (01-06-2010)“…Periventricular leukomalacia (PVL) is a major form of brain damage in premature infants. This study was to test whether IGF-1 can prevent PVL-like brain damage…”
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Comparative Survival Analysis of Invasive Breast Cancer Patients Treated by a U.S. Military Medical Center and Matched Patients From the U.S. General Population
Published in Military medicine (01-11-2017)“…Many differences between U.S. military beneficiaries and the U.S. general population, including differences in health care access, are known factors affecting…”
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Dexamethasone and betamethasone protect against lipopolysaccharide-induced brain damage in neonatal rats
Published in Pediatric research (01-05-2012)“…Introduction: The aim of this study was to test whether dexamethasone (Dex) and betamethasone (Beta), two of the most commonly used corticosteroids, protect…”
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Positive Association of Fibroadenomatoid Change with HER2-Negative Invasive Breast Cancer: A Co-Occurrence Study
Published in PloS one (22-06-2015)“…Risk assessment of a benign breast disease/lesion (BBD) for invasive breast cancer (IBC) is typically done through a longitudinal study. For an…”
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Molecular alterations associated with breast cancer mortality
Published in PloS one (04-10-2012)“…Breast cancer is a heterogeneous disease and patients with similar pathologies and treatments may have different clinical outcomes. Identification of molecular…”
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Selenium and sulforaphane modify the expression of selenoenzymes in the human endothelial cell line EAhy926 and protect cells from oxidative damage
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-02-2007)“…Abstract Objective We examined the ability of sulforaphane and selenium to modify the expression of thioredoxin reductase (TR-1) and the glutathione…”
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Comparative analysis of differentially abundant proteins quantified by LC–MS/MS between flash frozen and laser microdissected OCT-embedded breast tumor samples
Published in Clinical proteomics (07-11-2020)“…Abstract Background Proteomic studies are typically conducted using flash-frozen (FF) samples utilizing tandem mass spectrometry (MS). However, FF specimens…”
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Synthesis and SAR studies of novel 2-(6-aminomethylaryl-2-aryl-4-oxo-quinazolin-3(4H)-yl)acetamide Vasopressin V₁b receptor antagonists
Published in Bioorganic & medicinal chemistry letters (15-06-2011)“…Synthesis and structure–activity relationships (SAR) of a novel series of vasopressin V₁b antagonists are described…”
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Abstract A29: Effects of lysophosphatidic acid on ovarian cancer metastatic dissemination
Published in Clinical cancer research (01-08-2018)“…Abstract Epithelial ovarian cancer (EOC) is typically detected after extensive intraperitoneal metastases, contributing to its status as the deadliest…”
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Abstract 2342: Multidimensional metabolomic stratification of ER+/HER2- compared to ER-/HER2- breast tumors
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract Introduction: In the United States, breast cancer represents the leading cancer diagnosis among women and can readily be classified as a metabolic…”
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