Paraneoplastic cutaneous manifestations: concepts and updates

The skin often signals systemic changes. Some neoplastic diseases that affect internal organs may trigger several cutaneous manifestations. Although these dermatoses are relatively unusual, the recognition of some typical paraneoplastic dermatoses may lead to the early diagnosis of a neoplasm and de...

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Bibliographic Details
Published in:	Anais brasileiros de dermatología Vol. 88; no. 1; pp. 9 - 22
Main Authors:	Silva, Josenilson Antônio da, Mesquita, Kleyton de Carvalho, Igreja, Ana Carolina de Souza Machado, Lucas, Isabella Cristina Rodrigues Naves, Freitas, Aline Ferreira, Oliveira, Sandra Maximiano de, Costa, Izelda Maria Carvalho, Campbell, Iphis Tenfuss
Format:	Journal Article
Language:	English
Published:	Brazil Sociedade Brasileira de Dermatologia 01-01-2013
Subjects:	Continued Medical Education DERMATOLOGY Education, Medical, Continuing Humans Necrosis Paraneoplastic Syndromes - complications Paraneoplastic Syndromes - pathology Prognosis Skin Diseases - etiology Skin Diseases - pathology Surveys and Questionnaires Manifestações cutâneas Neoplasias Paraneoplastic syndromes Skin manifestations Síndromes paraneoplásicas Neoplasms
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Summary:	The skin often signals systemic changes. Some neoplastic diseases that affect internal organs may trigger several cutaneous manifestations. Although these dermatoses are relatively unusual, the recognition of some typical paraneoplastic dermatoses may lead to the early diagnosis of a neoplasm and determine a better prognosis. In this review article, we discuss the paraneoplastic cutaneous manifestations strongly associated with neoplasms, which include acanthosis nigricans maligna, tripe palms, erythema gyratum repens, Bazex syndrome, acquired hypertrichosis lanuginosa, necrolytic migratory erythema, Leser-Trélat sign and paraneoplastic pemphigus. We also review the clinical manifestations of each condition and include updated knowledge on disease pathogenesis.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	0365-0596 1806-4841 1806-4841 0365-0596
DOI:	10.1590/s0365-05962013000100001