Search Results - "Campbell, Ewan M"
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Dendrimer-coated carbon nanotubes deliver dsRNA and increase the efficacy of gene knockdown in the red flour beetle Tribolium castaneum
Published in Scientific reports (24-07-2020)“…In this study, the use of dendrimer-coated carbon nanotubes (CNTs) as a delivery vehicle for dsRNA was assessed in Tribolium castaneum . Exposure to low…”
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Structure, function and translational relevance of aquaporin dual water and ion channels
Published in Molecular aspects of medicine (01-10-2012)“…Aquaporins have been assumed to be selective for water alone, and aquaglyceroporins are accepted as carrying water and small uncharged solutes including…”
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A salivary chitinase of Varroa destructor influences host immunity and mite's survival
Published in PLoS pathogens (01-12-2020)“…Varroa destructor is an ectoparasite of honey bees and an active disease vector, which represents one of the most severe threats for the beekeeping industry…”
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Green Bees: Reverse Genetic Analysis of Deformed Wing Virus Transmission, Replication, and Tropism
Published in Viruses (12-05-2020)“…Environmental and agricultural pollination services by honey bees, , and honey production are compromised by high levels of annual colony losses globally. The…”
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Transcriptome analysis of the synganglion from the honey bee mite, Varroa destructor and RNAi knockdown of neural peptide targets
Published in Insect biochemistry and molecular biology (01-03-2016)“…Varroa mites (Varroa destructor) and the viruses that they transmit are one of the major contributing factors to the global honey bee crisis. Gene products…”
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A real-time PCR method for quantification of the total and major variant strains of the deformed wing virus
Published in PloS one (19-12-2017)“…European honey bees (Apis mellifera) are critically important to global food production by virtue of their pollination services but are severely threatened by…”
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A Toolbox for Quantitative Gene Expression in Varroa destructor: RNA Degradation in Field Samples and Systematic Analysis of Reference Gene Stability
Published in PloS one (16-05-2016)“…Varroa destructor is the major pest of Apis mellifera and contributes to the global honey bee health crisis threatening food security. Developing new control…”
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Quantitative and Qualitative Changes in the Deformed Wing Virus Population in Honey Bees Associated with the Introduction or Removal of Varroa destructor
Published in Viruses (22-07-2022)“…Varroa destructor is an ectoparasitic mite associated with significant losses of honeybee colonies globally. The mite vectors a range of pathogenic viruses,…”
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Role of an aquaporin in the sheep tick Ixodes ricinus: Assessment as a potential control target
Published in International journal for parasitology (2010)“…Ticks undergo tremendous osmoregulatory stress as they take on up to 100 times their body weight in blood, returning about 75% of the ingested water and ions…”
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Gene-knockdown in the honey bee mite Varroa destructor by a non-invasive approach: studies on a glutathione S-transferase
Published in Parasites & vectors (16-08-2010)“…BACKGROUND: The parasitic mite Varroa destructor is considered the major pest of the European honey bee (Apis mellifera) and responsible for declines in honey…”
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Identification and characterization of functional aquaporin water channel protein from alimentary tract of whitefly, Bemisia tabaci
Published in Insect biochemistry and molecular biology (01-03-2011)“…Some hemipteran xylem and phloem-feeding insects have evolved specialized alimentary structures or filter chambers that rapidly transport water for excretion…”
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Identification, functional characterization and expression patterns of a water-specific aquaporin in the brown dog tick, Rhipicephalus sanguineus
Published in Insect biochemistry and molecular biology (01-02-2009)“…Much is known about the physiology of tick salivation, but nothing is known about the movement of water through the cell membranes of salivary glands, a…”
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Differential Inhibition of Water and Ion Channel Activities of Mammalian Aquaporin-1 by Two Structurally Related Bacopaside Compounds Derived from the Medicinal Plant Bacopa monnieri
Published in Molecular pharmacology (01-10-2016)“…Aquaporin-1 (AQP1) is a major intrinsic protein that facilitates flux of water and other small solutes across cell membranes. In addition to its function as a…”
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Invertebrate aquaporins: a review
Published in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology (01-11-2008)“…Aquaporins (AQPs) or water channels render the lipid bilayer of cell membranes permeable to water. The numerous AQP subtypes present in any given species, the…”
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Cyclical DNA Methyltransferase 3a Expression Is a Seasonal and Estrus Timer in Reproductive Tissues
Published in Endocrinology (Philadelphia) (01-06-2016)“…It is becoming clear that epigenetic modifications such as DNA methylation can be dynamic and, in many cases, reversible. Here we investigated the photoperiod…”
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The activity of human aquaporin 1 as a cGMP-gated cation channel is regulated by tyrosine phosphorylation in the carboxyl-terminal domain
Published in Molecular pharmacology (01-01-2012)“…In addition to a constitutive water channel activity, several studies suggest Aquaporin-1 (AQP1) functions as a nonselective monovalent cation channel…”
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RNA interference in the cat flea, Ctenocephalides felis: Approaches for sustained gene knockdown and evidence of involvement of Dicer-2 and Argonaute2
Published in International journal for parasitology (01-11-2018)“…[Display omitted] •First known demonstration of gene knockdown in a flea, the cat flea (Ctenocephalides felis)•Strong, transient gene knockdown by immersion in…”
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AqF026 Is a Pharmacologic Agonist of the Water Channel Aquaporin-1
Published in Journal of the American Society of Nephrology (01-07-2013)“…Aquaporin-1 (AQP1) facilitates the osmotic transport of water across the capillary endothelium, among other cell types, and thereby has a substantial role in…”
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Reference gene selection and RNA preservation protocol in the cat flea, Ctenocephalides felis, for gene expression studies
Published in Parasitology (01-10-2016)“…The cat flea, Ctenocephalides felis, is a major pest species on companion animals thus of significant importance to the animal health industry. The aim of this…”
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Water and urea permeation pathways of the human excitatory amino acid transporter EAAT1
Published in Biochemical journal (15-10-2011)“…Glutamate transport is coupled to the co-transport of 3 Na(+) and 1 H(+) followed by the counter-transport of 1 K(+). In addition, glutamate and Na(+) binding…”
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