Search Results - "Campanucci, Verónica A."
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Voltage-gated sodium channels in diabetic sensory neuropathy: Function, modulation, and therapeutic potential
Published in Frontiers in cellular neuroscience (17-11-2022)“…Voltage-gated sodium channels (Na V ) are the main contributors to action potential generation and essential players in establishing neuronal excitability. Na…”
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2
RAGE signaling is required for AMPA receptor dysfunction in the hippocampus of hyperglycemic mice
Published in Physiology & behavior (01-02-2021)“…•Diabetes in humans has long been associated with cognitive dysfunction.•Role of RAGE it still unknown in diabetes-induced cognitive dysfunction.•We found…”
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3
Hyperglycemia induces RAGE-dependent hippocampal spatial memory impairments
Published in Physiology & behavior (01-02-2021)“…•Diabetes has been shown to affect cognitive function such as learning and memory.•Role of RAGE it still unknown in diabetes-induced cognitive dysfunction.•We…”
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4
RAGE-dependent potentiation of TRPV1 currents in sensory neurons exposed to high glucose
Published in PloS one (23-02-2018)“…Diabetes mellitus is associated with sensory abnormalities, including exacerbated responses to painful (hyperalgesia) or non-painful (allodynia) stimuli. These…”
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5
Lipopolysaccharides induce a RAGE-mediated sensitization of sensory neurons and fluid hypersecretion in the upper airways
Published in Scientific reports (16-04-2021)“…Thoracic dorsal root ganglia (tDRG) contribute to fluid secretion in the upper airways. Inflammation potentiates DRG responses, but the mechanisms remain under…”
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6
Pseudomonas aeruginosa triggers CFTR-mediated airway surface liquid secretion in swine trachea
Published in Proceedings of the National Academy of Sciences - PNAS (02-09-2014)“…Cystic fibrosis (CF) is an autosomal recessive genetic disorder caused by mutations in the gene encoding for the anion channel cystic fibrosis transmembrane…”
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Mitochondrial Reactive Oxygen Species Inactivate Neuronal Nicotinic Acetylcholine Receptors and Induce Long-Term Depression of Fast Nicotinic Synaptic Transmission
Published in The Journal of neuroscience (13-02-2008)“…Neuronal nicotinic acetylcholine receptors (nAChRs), ligand-gated ion channels implicated in a variety of cognitive, motor, and sensory behaviours, are…”
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8
RAGE mediates the inactivation of nAChRs in sympathetic neurons under high glucose conditions
Published in The European journal of neuroscience (01-02-2015)“…Autonomic dysfunction is a serious complication of diabetes and can lead to cardiovascular abnormalities and premature death. It was recently proposed that…”
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9
Modulation of the carotid body sensory discharge by NO: An up-dated hypothesis
Published in Respiratory physiology & neurobiology (15-11-2012)“…Abstract The carotid body (CB) is a peripheral chemoreceptor organ that initiates compensatory reflex responses so as to maintain gas homeostasis. Stimuli such…”
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10
Autonomic innervation of the carotid body: Role in efferent inhibition
Published in Respiratory physiology & neurobiology (01-07-2007)“…Abstract The carotid body (CB) is a chemosensory organ that monitors blood chemicals and initiates compensatory reflex adjustments to maintain homeostasis. The…”
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11
Identification of a single amino acid in GluN1 that is critical for glycine-primed internalization of NMDA receptors
Published in Molecular brain (13-08-2013)“…NMDA receptors are ligand-gated ion channels with essential roles in glutamatergic synaptic transmission and plasticity in the CNS. As co-receptors for…”
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12
Purinergic stimulation of carotid body efferent glossopharyngeal neurones increases intracellular Ca2+ and nitric oxide production
Published in Experimental physiology (01-07-2013)“…New Findings • What is the central question of this study? Nitric oxide is a strong modulator of carotid body (CB) chemoreceptor activity; however, the…”
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13
Expression of Multiple P2X Receptors by Glossopharyngeal Neurons Projecting to Rat Carotid Body O2-Chemoreceptors: Role in Nitric Oxide-Mediated Efferent Inhibition
Published in The Journal of neuroscience (13-09-2006)“…In mammals, ventilation is peripherally controlled by the carotid body (CB), which receives afferent innervation from the petrosal ganglion and efferent…”
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14
Cystic fibrosis swine fail to secrete airway surface liquid in response to inhalation of pathogens
Published in Nature communications (05-10-2017)“…Cystic fibrosis is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) channel, which can result in chronic…”
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15
cAMP triggers Na+ absorption by distal airway surface epithelium in cystic fibrosis swine
Published in Cell reports (Cambridge) (05-10-2021)“…A controversial hypothesis pertaining to cystic fibrosis (CF) lung disease is that the CF transmembrane conductance regulator (CFTR) channel fails to inhibit…”
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16
Expression of Multiple P2X Receptors by Glossopharyngeal Neurons Projecting to Rat Carotid Body O 2 -Chemoreceptors: Role in Nitric Oxide-Mediated Efferent Inhibition
Published in The Journal of neuroscience (13-09-2006)“…In mammals, ventilation is peripherally controlled by the carotid body (CB), which receives afferent innervation from the petrosal ganglion and efferent…”
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17
33-LB: Role of Cav3.2 Channels in Sensory Neuron Abnormalities during Early Hyperglycemia
Published in Diabetes (New York, N.Y.) (01-06-2020)“…Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes. It is characterized by a constellation of sensory abnormalities, including…”
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123-OR: Short-Term Hyperglycemia Causes a Paradoxical Reduction in Sensory Neuron Excitability
Published in Diabetes (New York, N.Y.) (01-06-2020)“…Peripheral neuropathy in diabetes is characterized by a constellation of sensory abnormalities, including numbness, tingling, as well as exacerbated responses…”
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Pulmonary Ionocytes Regulate Airway Surface Liquid pH in Primary Human Bronchial Epithelial Cells
Published in American journal of respiratory and critical care medicine (15-09-2024)“…Pulmonary ionocytes are a newly discovered airway epithelial cell type proposed to be a major contributor to cystic fibrosis (CF) lung disease based on…”
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20
A novel O2-sensing mechanism in rat glossopharyngeal neurones mediated by a halothane-inhibitable background K+ conductance
Published in The Journal of physiology (01-05-2003)“…Modulation of K + channels by hypoxia is a common O 2 -sensing mechanism in specialised cells. More recently, acid-sensitive TASK-like background K + channels,…”
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