Search Results - "Campanera, Josep M"

Dimerization Mechanism of Alzheimer Aβ40 Peptides: The High Content of Intrapeptide-Stabilized Conformations in A2V and A2T Heterozygous Dimers Retards Amyloid Fibril Formation by Nguyen, Phuong H, Sterpone, Fabio, Pouplana, Ramon, Derreumaux, Philippe, Campanera, Josep M

“…Amyloid beta (Aβ) oligomerization is associated with the origin and progression of Alzheimer’s disease (AD). While the A2V mutation enhances aggregation…”
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General Rule for the Stabilization of Fullerene Cages Encapsulating Trimetallic Nitride Templates by Campanera, Josep M., Bo, Carles, Poblet, Josep M.

“…Ruling the cage: The bonding in trimetallic nitride template (TNT) endohedral metallofullerenes is widely described by the ionic model Sc3N6+@Ck6−. The ability…”
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Impact of the A2V Mutation on the Heterozygous and Homozygous Aβ1–40 Dimer Structures from Atomistic Simulations by Nguyen, Phuong H, Sterpone, Fabio, Campanera, Josep M, Nasica-Labouze, Jessica, Derreumaux, Philippe

“…The A2V mutation was reported to protect from Alzheimer’s disease in its heterozygous form and cause an early Alzheimer’s disease type dementia in its…”
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MMPBSA decomposition of the binding energy throughout a molecular dynamics simulation of amyloid-beta (Abeta(10-35)) aggregation by Campanera, Josep M, Pouplana, Ramon

“…Recent experiments with amyloid-beta (Abeta) peptides indicate that the formation of toxic oligomers may be an important contribution to the onset of…”
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(Sustainable) quality of life in English city locations by Higgins, Paul, Campanera, Josep M.

“…► Introduces ‘public-based’ notion of sustainable quality of life. ► Explores different ways of operationalising sustainable quality of life. ► Reports…”
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Chemical Reactivity of D3h C78 (Metallo)Fullerene: Regioselectivity Changes Induced by Sc3N Encapsulation by OSUNA, Sílvia, SWART, Marcel, CAMPANERA, Josep M., POBLET, Josep M., SOLà, Miquel

“…We report here for the first time a full comparison of the exohedral reactivity of a given fullerene and its parent trinitride template endohedral…”
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Exohedral Reactivity of Trimetallic Nitride Template (TNT) Endohedral Metallofullerenes by Campanera, Josep M, Bo, Carles, Poblet, Josep M

“…Fullerenes containing a trimetallic nitride template (TNT) within the cage are a particularly interesting class of endohedral metallofullerenes. Recently two…”
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First diastereoselective [3 + 2] cycloaddition reaction of diethyl isocyanomethylphosphonate and maleimides by Arróniz, Carlos, Molina, Juan, Abás, Sonia, Molins, Elies, Campanera, Josep M, Luque, F Javier, Escolano, Carmen

“…Bicyclic α-iminophosphonates were prepared via the first diastereoselective silver catalyzed [3 + 2] cycloaddition reaction of diethyl…”
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Tetrameric Aβ40 and Aβ42 β‑Barrel Structures by Extensive Atomistic Simulations. II. In Aqueous Solution by Nguyen, Phuong H, Campanera, Josep M, Ngo, Son Tung, Loquet, Antoine, Derreumaux, Philippe

“…Alzheimer’s disease (AD) is characterized by the accumulation of extracellular Aβ42 and Aβ40 oligomers and plaques. In a recent computational study, we found…”
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Molecular Modeling of the Reduction Mechanism in the Citrate-Mediated Synthesis of Gold Nanoparticles by Ojea-Jiménez, Isaac, Campanera, Josep M

“…The synthesis of gold nanoparticles (Au NPs) via the reduction of tetrachloroauric acid by sodium citrate has become a standard procedure in nanotechnology…”
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The ortho-Substituent Effect on the Ag-Catalysed Decarboxylation of Benzoic Acids by Grainger, Rachel, Cornella, Josep, Blakemore, David C., Larrosa, Igor, Campanera, Josep M.

“…A combined experimental and computational investigation on the Ag‐catalysed decarboxylation of benzoic acids is reported herein. The present study demonstrates…”
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Tetrameric Aβ40 and Aβ42 β‑Barrel Structures by Extensive Atomistic Simulations. I. In a Bilayer Mimicking a Neuronal Membrane by Nguyen, Phuong H, Campanera, Josep M, Ngo, Son Tung, Loquet, Antoine, Derreumaux, Philippe

“…The amyloid-β (Aβ) 42 oligomers are much more toxic than Aβ40 oligomers in Alzheimer’s disease. Numerous experiments indicate that toxicity could involve the…”
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Development of a Structure-Based, pH-Dependent Lipophilicity Scale of Amino Acids from Continuum Solvation Calculations by Zamora, William J, Campanera, Josep M, Luque, F. Javier

“…Lipophilicity is a fundamental property to characterize the structure and function of proteins, motivating the development of lipophilicity scales. We report a…”
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Prediction of pH-Dependent Hydrophobic Profiles of Small Molecules from Miertus–Scrocco–Tomasi Continuum Solvation Calculations by Zamora, William J, Curutchet, Carles, Campanera, Josep M, Luque, F. Javier

“…Hydrophobicity is a key physicochemical descriptor used to understand the biological profile of (bio)­organic compounds as well as a broad variety of…”
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Synthesis and biological properties of aryl methyl sulfones by Navarro, Lorena, Rosell, Gloria, Sánchez, Silvia, Boixareu, Núria, Pors, Klaus, Pouplana, Ramon, Campanera, Josep M., Pujol, M. Dolors

“…[Display omitted] •Aryl methyl sulfones related to classical AINEs were designed and synthesized.•Anti-inflammatory activity was evaluated in classical assays…”
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Mass Spectrometric and Computational Studies of Heterofullerenes ([C58Pt]-, [C59Pt]+) Obtained by Laser Ablation of Electrochemically Deposited Films by Hayashi, Akari, Xie, Yongming, Poblet, Josep M, Campanera, Josep M, Lebrilla, Carlito B, Balch, Alan L

“…Fullerenes with metal atoms substituted into the carbon framework have been observed in laser ablation studies of electrochemically prepared C60/Pt or…”
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Dimerization Mechanism of Alzheimer Aβ 40 Peptides: The High Content of Intrapeptide-Stabilized Conformations in A2V and A2T Heterozygous Dimers Retards Amyloid Fibril Formation by Nguyen, Phuong H, Sterpone, Fabio, Pouplana, Ramon, Derreumaux, Philippe, Campanera, Josep M

“…Amyloid beta (Aβ) oligomerization is associated with the origin and progression of Alzheimer's disease (AD). While the A2V mutation enhances aggregation…”
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The Relationship Between Residential Quality of Life and Socioeconomic Status in England by Campanera, Josep M., Nobajas, Alexandre, Higgins, Paul

“…This article explores the quintessential “person–environment” relationship that forms the core of the subdiscipline of social geography within the context of a…”
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Allosteric regulation of PKCθ: Understanding multistep phosphorylation and priming by ligands in AGC kinases by Seco, Jesus, Ferrer-Costa, Carles, Campanera, Josep M., Soliva, Robert, Barril, Xavier

“…Protein kinases play critical roles in cellular activation and differentiation, and are involved in numerous pathophysiological processes. As a critical…”
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Proline cis-trans isomerization and its implications for the dimerization of analogues of cyclopeptide stylostatin 1: a combined computational and experimental study by López-Martínez, C, Flores-Morales, P, Cruz, M, González, T, Feliz, M, Diez, A, Campanera, Josep M

“…Cis and trans proline conformers are often associated with dramatic changes in the biological function of peptides. A slow equilibrium between cis and trans…”
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