Search Results - "Campana, Raffaela"

Vaccine development for allergen-specific immunotherapy based on recombinant allergens and synthetic allergen peptides: Lessons from the past and novel mechanisms of action for the future by Valenta, Rudolf, MD, Campana, Raffaela, PhD, Focke-Tejkl, Margit, PhD, Niederberger, Verena, MD

“…In the past, the development of more effective, safe, convenient, broadly applicable, and easy to manufacture vaccines for allergen-specific immunotherapy…”
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Preventive Allergen-Specific Vaccination Against Allergy: Mission Possible? by Tulaeva, Inna, Kratzer, Bernhard, Campana, Raffaela, Curin, Mirela, van Hage, Marianne, Karsonova, Antonina, Riabova, Ksenja, Karaulov, Alexander, Khaitov, Musa, Pickl, Winfried F, Valenta, Rudolf

“…Vaccines for infectious diseases have improved the life of the human species in a tremendous manner. The principle of vaccination is to establish adaptive…”
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Microarray-Based Allergy Diagnosis: Quo Vadis? by Huang, Huey-Jy, Campana, Raffaela, Akinfenwa, Oluwatoyin, Curin, Mirela, Sarzsinszky, Eszter, Karsonova, Antonina, Riabova, Ksenja, Karaulov, Alexander, Niespodziana, Katarzyna, Elisyutina, Olga, Fedenko, Elena, Litovkina, Alla, Smolnikov, Evgenii, Khaitov, Musa, Vrtala, Susanne, Schlederer, Thomas, Valenta, Rudolf

“…More than 30% of the world population suffers from allergy. Allergic individuals are characterized by the production of immunoglobulin E (IgE) antibodies…”
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Frequent occurrence of T cell–mediated late reactions revealed by atopy patch testing with hypoallergenic rBet v 1 fragments by Campana, Raffaela, PhD, Moritz, Katharina, MD, Marth, Katharina, MD, Neubauer, Angela, PhD, Huber, Hans, PhD, Henning, Rainer, PhD, Blatt, Katharina, PhD, Hoermann, Gregor, MD, PhD, Brodie, Tess M., PhD, Kaider, Alexandra, MSc, Valent, Peter, MD, Sallusto, Federica, PhD, Wöhrl, Stefan, MD, MSc, Valenta, Rudolf, MD

“…Background Late allergic reactions are common in the course of allergen-specific immunotherapy and even occur with allergy vaccines with reduced IgE…”
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Preventive Administration of Non-Allergenic Bet v 1 Peptides Reduces Allergic Sensitization to Major Birch Pollen Allergen, Bet v 1 by Akinfenwa, Oluwatoyin, Huang, Huey-Jy, Linhart, Birgit, Focke-Tejkl, Margarete, Vrtala, Susanne, Poroshina, Alina, Nikonova, Alexandra, Khaitov, Musa, Campion, Nicholas J, Eckl-Dorna, Julia, Niederberger-Leppin, Verena, Kratzer, Bernhard, Tauber, Peter Anton, Pickl, Winfried F, Kundi, Michael, Campana, Raffaela, Valenta, Rudolf

“…IgE-mediated allergy to birch pollen affects more than 100 million patients world-wide. Bet v 1, a 17 kDa protein is the major allergen in birch pollen…”
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Dissection of the IgE and T-cell recognition of the major group 5 grass pollen allergen Phl p 5 by Focke-Tejkl, Margarete, PhD, Campana, Raffaela, PhD, Reininger, Renate, PhD, Lupinek, Christian, MD, Blatt, Katharina, MSc, Valent, Peter, MD, Pavkov-Keller, Tea, PhD, Keller, Walter, PhD, Valenta, Rudolf, MD

“…Background The major timothy grass pollen allergen Phl p 5 belongs to the most potent allergens involved in hay fever and asthma. Objective This study…”
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Non-IgE-reactive allergen peptides deteriorate the skin barrier in house dust mite-sensitized atopic dermatitis patients by Pfisterer, Karin, Wielscher, Matthias, Samardzic, David, Weinzettl, Pauline, Symmank, Dorte, Shaw, Lisa E., Campana, Raffaela, Huang, Huey-Jy, Farlik, Matthias, Bangert, Christine, Vrtala, Susanne, Valenta, Rudolf, Weninger, Wolfgang

“…Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by type 2 cytokine-driven skin inflammation and epithelial barrier dysfunction. The…”
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Genetic engineering of trimers of hypoallergenic fragments of the major birch pollen allergen, Bet v 1, for allergy vaccination by Vrtala, Susanne, Fohr, Monika, Campana, Raffaela, Baumgartner, Christian, Valent, Peter, Valenta, Rudolf

“…Abstract An immunotherapy trial performed in allergic patients with hypoallergenic recombinant fragments, comprising aa 1–74 and 75–160 of the major birch…”
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Hypoallergenic derivatives of the major birch pollen allergen Bet v 1 obtained by rational sequence reassembly by Campana, Raffaela, PhD, Vrtala, Susanne, PhD, Maderegger, Bernhard, PhD, Jertschin, Peter, PhD, Stegfellner, Gottfried, PhD, Swoboda, Ines, PhD, Focke-Tejkl, Margarete, PhD, Blatt, Katharina, Gieras, Anna, MSc, Zafred, Domen, BSc, Neubauer, Angela, PhD, Valent, Peter, MD, Keller, Walter, PhD, Spitzauer, Susanne, MD, Valenta, Rudolf, MD

“…Background At least 100 million patients suffer from birch pollen allergy. Objective Rational design of recombinant derivatives of the major birch pollen…”
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Non–IgE-mediated chronic allergic skin inflammation revealed with rBet v 1 fragments by Campana, Raffaela, MSc, Mothes, Nadine, MD, Rauter, Ingrid, PhD, Vrtala, Susanne, PhD, Reininger, Renate, PhD, Focke-Tejkl, Margarete, PhD, Lupinek, Christian, MD, Balic, Nadja, Spitzauer, Susanne, MD, Valenta, Rudolf, MD

“…Patients with AD with high levels of IgE express higher levels of FcεRI on monocytes and dendritic cells, and it has been demonstrated in vitro that…”
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Recombinant allergy vaccines based on allergen-derived B cell epitopes by Valenta, Rudolf, Campana, Raffaela, Niederberger, Verena

“…Highlights • More than 25% of population suffers from IgE-associated allergy. • Allergen-specific immunotherapy is the only disease-modifying allergy…”
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Next-Generation of Allergen-Specific Immunotherapies: Molecular Approaches by Curin, Mirela, Khaitov, Musa, Karaulov, Alexander, Namazova-Baranova, Leyla, Campana, Raffaela, Garib, Victoria, Valenta, Rudolf

“…Purpose of Review The aim of this article is to discuss how allergen-specific immunotherapy (AIT) can be improved through molecular approaches. We provide a…”
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Novel vaccines for allergen-specific immunotherapy by Akinfenwa, Oluwatoyin, Rodríguez-Domínguez, Azahara, Vrtala, Susanne, Valenta, Rudolf, Campana, Raffaela

“…Allergen-specific immunotherapy (AIT) is a highly economic, effective and disease-modifying form of allergy treatment but requires accurate prescription and…”
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Molecular aspects of allergens in atopic dermatitis by Campana, Raffaela, Dzoro, Sheron, Mittermann, Irene, Fedenko, Elena, Elisyutina, Olga, Khaitov, Musa, Karaulov, Alexander, Valenta, Rudolf

“…PURPOSE OF REVIEWMolecular allergology uses pure, mainly recombinant and structurally defined allergen molecules and allergen-derived epitopes to study…”
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Bet v 1‐specific IgE levels and PR‐10 reactivity discriminate silent sensitization from phenotypes of birch allergy by Elisyutina, Olga, Fedenko, Elena, Campana, Raffaela, Litovkina, Alla, Ilina, Nataliya, Kudlay, Dmitry, Egorenkov, Evgenii, Smirnov, Valeriy, Valenta, Rudolf, Lupinek, Christian, Khaitov, Musa

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Determination of IgE and IgG reactivity to more than 170 allergen molecules in paper-dried blood spots by Garib, Victoria, Rigler, Eva, Gastager, Felix, Campana, Raffaela, Dorofeeva, Yulia, Gattinger, Pia, Zhernov, Yury, Khaitov, Musa, Valenta, Rudolf

“…The demographic and clinical characterization of the 17 patients (ie, #1-#18) is presented in Table E2 in this article's Online Repository at…”
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Allergen Extracts for In Vivo Diagnosis and Treatment of Allergy: Is There a Future? by Valenta, Rudolf, Karaulov, Alexander, Niederberger, Verena, Zhernov, Yury, Elisyutina, Olga, Campana, Raffaela, Focke-Tejkl, Margarete, Curin, Mirela, Namazova-Baranova, Leyla, Wang, Jiu-Yao, Pawankar, Ruby, Khaitov, Musa

“…Today, in vivo allergy diagnosis and allergen-specific immunotherapy (AIT) are still based on allergen extracts obtained from natural allergen sources. Several…”
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Natural human Bet v 1‐specific IgG antibodies recognize non‐conformational epitopes whereas IgE reacts with conformational epitopes by Brazhnikov, Georgii, Smolnikov, Evgenii, Litovkina, Alla, Jiang, Tianchi, Shatilov, Artem, Tulaeva, Inna, Tulaev, Mikhail, Karaulov, Alexander, Poroshina, Alina, Zhernov, Yury, Focke‐Tejkl, Margarete, Weber, Milena, Akinfenwa, Oluwatoyin, Elisyutina, Olga, Andreev, Sergey, Shilovskiy, Igor, Shershakova, Nadezhda, Smirnov, Valeriy, Fedenko, Elena, Lepeshkova, Tatiana Sergeevna, Beltyukov, Evgeny Cronidovich, Naumova, Veronika Victorovna, Kundi, Michael, Khaitov, Musa, Wiedermann, Ursula, Valenta, Rudolf, Campana, Raffaela

“…Background The nature of epitopes on Bet v 1 recognized by natural IgG antibodies of birch pollen allergic patients and birch pollen‐exposed but non‐sensitized…”
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Vaccination of nonallergic individuals with recombinant hypoallergenic fragments of birch pollen allergen Bet v 1: Safety, effects, and mechanisms by Campana, Raffaela, Marth, Katharina, Zieglmayer, Petra, Weber, Milena, Lupinek, Christian, Zhernov, Yury, Elisyutina, Olga, Khaitov, Musa, Rigler, Eva, Westritschnig, Kerstin, Berger, Uwe, Wolkersdorfer, Martin, Horak, Fritz, Horak, Friedrich, Valenta, Rudolf

“…Most of the subjects vaccinated with the rBet v 1 fragments developed IgG against Bet v 1 and both fragments after the second injection and a significant…”
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Allergic sensitization to Mal d 1 without detectable specific serum IgE by Litovkina, Alla, Byazrova, Maria, Smolnikov, Evgenii, Nikonova, Alexandra, Elisyutina, Olga, Fedenko, Elena, Ilina, Nataliya, Akinfenwa, Oluwatoyin, Campana, Raffaela, Kudlay, Dmitry, Valenta, Rudolf, Khaitov, Musa

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