Search Results - "Campagnoni, C."
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The Human Myelin Basic Protein Gene is Included within a 179-Kilobase Transcription Unit: Expression in the Immune and Central Nervous Systems
Published in Proceedings of the National Academy of Sciences - PNAS (15-11-1993)“…Two human Golli (for gene expressed in the oligodendrocyte lineage)-MBP (for myelin basic protein) cDNAs have been isolated from a human oligodendroglioma cell…”
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The major myelin protein genes are expressed in the human thymus
Published in Journal of neuroscience research (15-09-1996)“…Demyelinating diseases, such as multiple sclerosis (MS) in man or experimental allergic encephalomyelitis (EAE) in rodents, may include an associated immune…”
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3
Myelin basic protein gene expression in neurons: developmental and regional changes in protein targeting within neuronal nuclei, cell bodies, and processes
Published in The Journal of neuroscience (15-04-1996)“…The myelin basic protein (MBP) gene is part of the golli-mbp gene complex. In mouse, the golli-mbp gene produces two families of mRNAs from different…”
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4
Thymocytes Express the golli Products of the Myelin Basic Protein Gene and Levels of Expression Are Stage Dependent
Published in The Journal of immunology (1950) (15-11-2000)“…The golli products of the myelin basic protein gene have been shown to be expressed in mouse thymus and brain. The full repertoire of thymic cell types…”
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The golli-myelin basic protein negatively regulates signal transduction in T lymphocytes
Published in Journal of neuroimmunology (01-07-2004)“…Protein kinase C (PKC) plays a critical role in signal transduction controlling T lymphocyte activation. Both positive and negative regulation of signal…”
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Expression of the myelin basic protein gene locus in neurons and oligodendrocytes in the human fetal central nervous system
Published in Journal of comparative neurology (1911) (21-10-1996)“…The myelin basic protein (MBP) gene locus is composed of two overlapping transcription units that share all of the MBP exons. One of these transcription units…”
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DM20 mRNA splice product of the myelin proteolipid protein gene is expressed in the murine heart
Published in Journal of neuroscience research (01-09-1992)“…Northern blot analysis of poly A(+) RNA isolated from mouse heart revealed the expression of 3.3 and 2.4 kb mRNAs that hybridized with a cDNA for the mouse…”
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Structure and expression of the mouse myelin proteolipid protein gene
Published in Journal of neuroscience research (1987)“…The gene for the mouse myelin proteolipid protein has been isolated and the seven exons have been sequenced. Since the sequence of a rat proteolipid protein…”
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Identification of a New Exon in the Myelin Proteolipid Protein Gene Encoding Novel Protein Isoforms That Are Restricted to the Somata of Oligodendrocytes and Neurons
Published in The Journal of neuroscience (01-10-1999)“…The myelin proteolipid protein (PLP) gene (i.e., the PLP/DM20 gene) has been of some interest because of its role in certain human demyelinating diseases, such…”
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Isolation and characterization of a zebra finch aromatase cDNA: in situ hybridization reveals high aromatase expression in brain
Published in Brain research. Molecular brain research. (01-07-1994)“…The brain regions controlling song are much larger in male than in female zebra finches. This sex difference is thought to arise developmentally when the…”
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Structure and developmental regulation of Golli-mbp, a 105-kilobase gene that encompasses the myelin basic protein gene and is expressed in cells in the oligodendrocyte lineage in the brain
Published in The Journal of biological chemistry (05-03-1993)“…We have identified a novel transcription unit of 105 kilobases (called the Golli-mbp gene) that encompasses the mouse myelin basic protein (MBP) gene. Three…”
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Autoreactive T Cells Can Be Protected from Tolerance Induction through Competition by Flanking Determinants for Access to Class II MHC
Published in Proceedings of the National Academy of Sciences - PNAS (29-04-2003)“…It is not clear why the N-terminal autoantigenic determinant of myelin basic protein (MBP), Ac1-9, is dominant in the B10.PL (H-2u) mouse, given its weak…”
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Embryonic Expression of the Myelin Basic Protein Gene: Identification of a Promoter Region That Targets Transgene Expression to Pioneer Neurons
Published in The Journal of neuroscience (15-09-1998)“…The myelin basic protein (MBP) gene produces two families of structurally related proteins from three different promoters-the golli products, generated from…”
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Identification of a protein that interacts with the golli-myelin basic protein and with nuclear LIM interactor in the nervous system
Published in Journal of neuroscience research (15-02-2004)“…The myelin basic protein (MBP) gene encodes the classic MBPs and the golli proteins, which are related structurally to the MBPs but are not components of the…”
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Expression of a novel transcript of the myelin basic protein gene
Published in Journal of neurochemistry (01-06-1990)“…A cDNA (M41) corresponding to a mouse myelin basic protein (MBP) mRNA with a longer 5'-untranslated region than predicted from earlier studies of MBP gene…”
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Experimental autoimmune encephalomyelitis relapses are reduced in heterozygous golli MBP knockout mice
Published in Journal of neuroimmunology (01-06-2003)“…Increased golli MBP (golli) expression has been observed in the peripheral immune system of mice in the relapsing phase of EAE, raising the possibility that…”
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Human T lymphocytes specific for the immunodominant 83-99 epitope of myelin basic protein: Recognition of golli MBP HOG 7
Published in Journal of neuroscience research (15-09-1996)“…Myelin basic protein (MBP) is a candidate auto‐antigen in the disease multiple sclerosis. Although MBP was thought to be sequestered behind the blood‐brain…”
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Expression of soma-restricted proteolipid/DM20 proteins in lymphoid cells
Published in Journal of neuroimmunology (01-11-2003)“…A new family of the myelin proteolipid protein (PLP/DM20) gene products, srPLP/DM20, has been identified recently in thymus and brain. In the central nervous…”
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Differential sensitivity in the survival of oligodendrocyte cell lines to overexpression of myelin proteolipid protein gene products
Published in Journal of neuroscience research (15-09-2001)“…The proteolipid (PLP) gene encodes at least four proteins, including the classic PLP and DM20, which are important components of the myelin sheath, and the…”
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Expression of the myelin proteolipid protein gene in the human fetal thymus
Published in Journal of neuroimmunology (01-07-1996)“…We have analyzed human fetal thymus and spleen for expression of the proteolipid protein (PLP) gene. We demonstrate that the PLP gene is transcribed in both…”
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