Search Results - "Campagna, Shawn"
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Metabolite discovery through global annotation of untargeted metabolomics data
Published in Nature methods (01-11-2021)“…Liquid chromatography–high-resolution mass spectrometry (LC-MS)-based metabolomics aims to identify and quantify all metabolites, but most LC-MS peaks remain…”
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Cryptic carbon and sulfur cycling between surface ocean plankton
Published in Proceedings of the National Academy of Sciences - PNAS (13-01-2015)“…Significance In the surface ocean, organic matter released by phytoplankton and degraded by heterotrophic bacteria is a key step in the carbon cycle. Compounds…”
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3
Dual stable isotopes enhance lipidomic studies in bacterial model organism Enterococcus faecalis
Published in Analytical and bioanalytical chemistry (01-07-2023)“…Dual stable isotope probes of deuterium oxide and 13 C fatty acid were demonstrated to probe the lipid biosynthesis cycle of a Gram-positive bacterium…”
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4
Composition of the gut microbiota modulates the severity of malaria
Published in Proceedings of the National Academy of Sciences - PNAS (23-02-2016)“…Plasmodium infections result in clinical presentations that range from asymptomatic to severe malaria, resulting in ∼1 million deaths annually. Despite this…”
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Discovery of Combustion‐Like in‐Source Oxidation of Linear Saturated Hydrocarbons Using GC‐APCI‐HRMS
Published in Journal of mass spectrometry. (01-10-2024)“…ABSTRACT Atmospheric pressure chemical ionization (APCI) is often used in the analysis of linear saturated hydrocarbons (LSHs) as this ionization technique…”
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Removal of peptidoglycan and inhibition of active cellular processes leads to daptomycin tolerance in Enterococcus faecalis
Published in PloS one (23-07-2021)“…Daptomycin is a cyclic lipopeptide antibiotic used in the clinic for treatment of severe enterococcal infections. Recent reports indicate that daptomycin…”
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Metabolome patterns identify active dechlorination in bioaugmentation consortium SDC-9
Published in Frontiers in microbiology (25-10-2022)“…Ultra-high performance liquid chromatography–high-resolution mass spectrometry (UPHLC–HRMS) is used to discover and monitor single or sets of biomarkers…”
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Safety and pharmacokinetics of naringenin: A randomized, controlled, single‐ascending‐dose clinical trial
Published in Diabetes, obesity & metabolism (01-01-2020)“…Aims To evaluate the safety and pharmacokinetics of naringenin in healthy adults consuming whole‐orange (Citrus sinensis) extract. Methods and methods In a…”
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Choline and choline metabolite patterns and associations in blood and milk during lactation in dairy cows
Published in PloS one (26-08-2014)“…Milk and dairy products are an important source of choline, a nutrient essential for human health. Infant formula derived from bovine milk contains a number of…”
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Alcohol-associated intestinal dysbiosis impairs pulmonary host defense against Klebsiella pneumoniae
Published in PLoS pathogens (12-06-2017)“…Chronic alcohol consumption perturbs the normal intestinal microbial communities (dysbiosis). To investigate the relationship between alcohol-mediated…”
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Recognition cascade and metabolite transfer in a marine bacteria‐phytoplankton model system
Published in Environmental microbiology (01-09-2017)“…Summary The trophic linkage between marine bacteria and phytoplankton in the surface ocean is a key step in the global carbon cycle, with almost half of marine…”
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Design and Evaluation of a Gas Chromatograph-Atmospheric Pressure Chemical Ionization Interface for an Exactive Orbitrap Mass Spectrometer
Published in Journal of the American Society for Mass Spectrometry (01-11-2019)“…Various separation and mass spectrometric (MS) techniques have furthered our ability to study complex mixtures, and the desire to measure every analyte in a…”
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Higher abundance of 2-dehydro- d -gluconate in the plasma of sub-fertile or infertile Bos taurus heifers
Published in Journal of animal science (03-01-2024)“…Abstract Infertility or subfertility impacts approximately 5% and 15% of dairy and beef heifers (Bos taurus), respectively. Heifers that do not produce a calf…”
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14
Riboneogenesis in Yeast
Published in Cell (10-06-2011)“…Glucose is catabolized in yeast via two fundamental routes, glycolysis and the oxidative pentose phosphate pathway, which produces NADPH and the essential…”
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Seasonally Relevant Cool Temperatures Interact with N Chemistry to Increase Microcystins Produced in Lab Cultures of Microcystis aeruginosa NIES-843
Published in Environmental science & technology (03-04-2018)“…Freshwater cyanobacterial blooms are regularly formed by Microcystis spp., which are well-known producers of the hepatotoxin microcystin. The environmental…”
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Metabolomic analysis of mouse prefrontal cortex reveals upregulated analytes during wakefulness compared to sleep
Published in Scientific reports (25-07-2018)“…By identifying endogenous molecules in brain extracellular fluid metabolomics can provide insight into the regulatory mechanisms and functions of sleep. Here…”
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Quorum sensing signal production and microbial interactions in a polymicrobial disease of corals and the coral surface mucopolysaccharide layer
Published in PloS one (30-09-2014)“…Black band disease (BBD) of corals is a complex polymicrobial disease considered to be a threat to coral reef health, as it can lead to mortality of massive…”
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Identification of 4‑Hydroxycumyl Alcohol As the Major MnO2‑Mediated Bisphenol A Transformation Product and Evaluation of Its Environmental Fate
Published in Environmental science & technology (19-05-2015)“…Bisphenol A (BPA), an environmental contaminant with weak estrogenic activity, resists microbial degradation under anoxic conditions but is susceptible to…”
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Evolution of the toxins muscarine and psilocybin in a family of mushroom-forming fungi
Published in PloS one (23-05-2013)“…Mushroom-forming fungi produce a wide array of toxic alkaloids. However, evolutionary analyses aimed at exploring the evolution of muscarine, a toxin that…”
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Key renal metabolic differences in healthy male and female Sprague Dawley rats
Published in The FASEB journal (01-05-2022)“…Introduction Understanding and identifying differences in biological processes between males and females are critical for developing the sex‐based treatments…”
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