Search Results - "Camp, RL"

CTGF, intestinal stellate cells and carcinoid fibrogenesis by Kidd, M, Modlin, I M, Shapiro, M D, Camp, R L, Mane, S M, Usinger, W, Murren, J R

“…To investigate the role of small intestinal carcinoid tumor-derived fibrotic mediators, TGFbeta1 and CTGF, in the mediation of fibrosis via activation of an…”
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X-tile: A new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization by CAMP, Robert L, DOLLED-FILHART, Marisa, RIMM, David L

“…The ability to parse tumors into subsets based on biomarker expression has many clinical applications; however, there is no global way to visualize the best…”
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Molecular Classification Identifies a Subset of Human Papillomavirus–Associated Oropharyngeal Cancers With Favorable Prognosis by Weinberger, Paul M, Yu, Ziwei, Haffty, Bruce G, Kowalski, Diane, Harigopal, Malini, Brandsma, Janet, Sasaki, Clarence, Joe, John, Camp, Robert L, Rimm, David L, Psyrri, Amanda

“…We sought to determine the prevalence of biologically relevant human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OSCC). Retinoblastoma (Rb)…”
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Automated Quantitative Analysis (AQUA) of In Situ Protein Expression, Antibody Concentration, and Prognosis by McCabe, Anthony, Dolled-Filhart, Marisa, Camp, Robert L., Rimm, David L.

“…Background: Disparate results in the immunohistochemistry literature regarding the relationship between biomarker expression and patient outcome decrease the…”
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Automated subcellular localization and quantification of protein expression in tissue microarrays by Rimm, David L, Camp, Robert L, Chung, Gina G

“…The recent development of tissue microarrays-composed of hundreds of tissue sections from different tumors arrayed on a single glass slide-facilitates rapid…”
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High levels of vascular endothelial growth factor and its receptors (VEGFR-1, VEGFR-2, neuropilin-1) are associated with worse outcome in breast cancer by Ghosh, Sriparna, PhD, Sullivan, Catherine A.W., MS, Zerkowski, Maciej P., BS, Molinaro, Annette M., PhD, Rimm, David L., MD, PhD, Camp, Robert L., MD, PhD, Chung, Gina G., MD

“…Summary Vascular endothelial growth factor has been shown to be up-regulated in breast cancers. Vascular endothelial growth factor receptors, VEGFR-1 and…”
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ras Mutations Are Associated With Aggressive Tumor Phenotypes and Poor Prognosis in Thyroid Cancer by GARCIA-ROSTAN, Ginesa, HONGYU ZHAO, CAMP, Robert L, POLLAN, Marina, HERRERO, Agustin, PARDO, Javier, RAN WU, CARCANGIU, Maria Luisa, COSTA, Jose, TALLINI, Giovanni

“…ras oncogenic activation has long been demonstrated in thyroid carcinomas of follicular cell derivation, but no consistent relationship has been shown between…”
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Validation of Tissue Microarray Technology in Breast Carcinoma by CAMP, Robert L, CHARETTE, Lori A, RIMM, David L

“…The recent development of tissue microarray technology has potentiated large-scale retrospective cohort studies using archival formalin-fixed,…”
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Quantitative analysis of breast cancer tissue microarrays shows that both high and normal levels of HER2 expression are associated with poor outcome by CAMP, Robert L, DOLLED-FILHART, Marisa, KING, Bonnie L, RIMM, David L

“…Using a tissue microarray cohort of 300 breast cancers and 84 samples of normal breast epithelium, we analyzed HER2/neu expression and compared traditional…”
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Tissue Microarray Analysis of Signal Transducers and Activators of Transcription 3 (Stat3) and Phospho-Stat3 (Tyr705) in Node-negative Breast Cancer Shows Nuclear Localization Is Associated with a Better Prognosis by DOLLED-FILHART, Marisa, CAMP, Robert L, KOWALSKI, Diane P, SMITH, Bradley L, RIMM, David L

“…Purpose: Although a high frequency of tumors contain constitutively activated signal transducers and activators of transcription 3 (Stat3), its relationship to…”
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Effect of Epidermal Growth Factor Receptor Expression Level on Survival in Patients with Epithelial Ovarian Cancer by PSYRRI, Amanda, KASSAR, Mohamad, ZIWEI YU, BAMIAS, Aris, WEINBERGER, Paul M, MARKAKIS, Sonia, KOWALSKI, Diane, CAMP, Robert L, RIMM, David L, DIMOPOULOS, Meletios A

“…Background: Several lines of laboratory evidence support the epidermal growth factor receptor (EGFR) as an adverse prognostic indicator in ovarian cancers…”
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Long-term preservation of antigenicity on tissue microarrays by DiVito, Kyle A, Charette, Lori A, Rimm, David L, Camp, Robert L

“…Tissue microarrays have facilitated the evaluation of large cohort studies; however, there is little data on the best method for preserving sections once they…”
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Tissue microarray analysis of hepatocyte growth factor/Met pathway components reveals a role for Met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer by KANG, Jung Y, DOLLED-FILHART, Marisa, OCAL, Idris Tolgay, SINGH, Baljit, LIN, Chen-Yong, DICKSON, Robert B, RIMM, David L, CAMP, Robert L

“…Numerous studies have demonstrated that overexpression of Met, the hepatocyte growth factor(HGF) receptor, plays an important role in tumorigenesis. Met…”
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Beta-catenin dysregulation in thyroid neoplasms: down-regulation, aberrant nuclear expression, and CTNNB1 exon 3 mutations are markers for aggressive tumor phenotypes and poor prognosis by Garcia-Rostan, G, Camp, R L, Herrero, A, Carcangiu, M L, Rimm, D L, Tallini, G

“…beta-catenin has a role in cell adhesion and Wnt signaling. It is mutated or otherwise dysregulated in a variety of human cancers. In this study we assess…”
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The role of genetic markers--NAP1L1, MAGE-D2, and MTA1--in defining small-intestinal carcinoid neoplasia by Kidd, Mark, Modlin, Irvin M, Mane, Shrikant M, Camp, Robert L, Eick, Geeta, Latich, Igor

“…Standard clinical and immunohistochemical methods cannot reliably determine whether a small intestinal carcinoid (SIC) is indolent or aggressive. We…”
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Quantitative determination of expression of the prostate cancer protein α-methylacyl-CoA racemase using automated quantitative analysis (AQUA) a novel: Paradigm for automated and continuous biomarker measurements by RUBIN, Mark A, ZERKOWSKI, Maciej P, CAMP, Robert L, KUEFER, Rainer, HOFER, Matthias D, CHINNAIYAN, Arul M, RIMM, David L

“…Despite years of discovery and attempts at validation, few molecular biomarkers achieve acceptance in the clinical setting. Tissue-based markers evaluated by…”
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Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: A tissue microarray study by WEN XIE, MERTENS, Joachim C, REISS, Daniel J, RIMM, David L, CAMP, Robert L, HAFFTY, Bruce G, REISS, Michael

“…Based largely on studies of cell lines in vitro and of transgenic mouse models, disruptions of transforming growth factor (TGF) beta signaling are thought to…”
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Macrophage Colony-Stimulating Factor-1 Receptor Expression Is Associated with Poor Outcome in Breast Cancer by Large Cohort Tissue Microarray Analysis by Kluger, Harriet M, Dolled-Filhart, Marisa, Rodov, Sofya, Kacinski, Barry M, Camp, Robert L, Rimm, David L

“…Purpose: Macrophage colony-stimulating factor-1 receptor (CSF-1R) is a transmembrane tyrosine kinase receptor, which is abnormally expressed in invasive breast…”
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Evaluating the Expression and Prognostic Value of TRAIL-R1 and TRAIL-R2 in Breast Cancer by MCCARTHY, Mary M, SZNOL, Mario, DIVITO, Kyle A, CAMP, Robert L, RIMM, David L, KLUGER, Harriet M

“…Purpose: The cell surface receptors tumor necrosis factor–related apoptosis-inducing ligand receptor 1 (TRAIL-R1) and TRAIL-R2 transmit apoptotic signals, and…”
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Microsatellite instability and gene mutations in transforming growth factor‐beta type II receptor are absent in small bowel carcinoid tumors by Kidd, Mark, Eick, Geeta, Shapiro, Michael D., Camp, Robert L., Mane, Shrikant M., Modlin, Irvin M.

“…BACKGROUND Microsatellite instability (MSI) with concomitant mutations in the coding region of transforming growth factor‐beta type II receptor (TGFβRII)…”
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