Search Results - "Camp, J J"
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Mapping human cell phenotypes to genotypes with single-cell genomics
Published in Science (American Association for the Advancement of Science) (27-09-2019)“…The cumulative activity of all of the body's cells, with their myriad interactions, life histories, and environmental experiences, gives rise to a condition…”
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Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration
Published in Science (American Association for the Advancement of Science) (26-10-2018)“…Amputation of the axolotl forelimb results in the formation of a blastema, a transient tissue where progenitor cells accumulate prior to limb regeneration…”
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Cellular Taxonomy of the Mouse Striatum as Revealed by Single-Cell RNA-Seq
Published in Cell reports (Cambridge) (26-07-2016)“…The striatum contributes to many cognitive processes and disorders, but its cell types are incompletely characterized. We show that microfluidic and FACS-based…”
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Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells
Published in Cell (08-10-2015)“…Intestinal Th17 cells are induced and accumulate in response to colonization with a subgroup of intestinal microbes such as segmented filamentous bacteria…”
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Optimizing Coilgun Geometry to Maximize Efficiency
Published in IEEE transactions on plasma science (01-10-2022)“…Naval Surface Warfare Center Dahlgren Division (NSWCDD) has been exploring methods of maximizing coilgun electrical-to-kinetic energy transfer efficiency by…”
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Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development
Published in eLife (26-09-2016)“…Human neocortex expansion likely contributed to the remarkable cognitive abilities of humans. This expansion is thought to primarily reflect differences in…”
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Optimizating the Energy Storage Configuration of a Single Stage Coilgun to Maximize Efficiency
Published in IEEE transactions on plasma science (01-05-2023)“…Naval Surface Warfare Center Dahlgren Division (NSWCDD) has been exploring methods of maximizing coilgun electrical-to-kinetic energy transfer efficiency by…”
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Single-cell genomics to guide human stem cell and tissue engineering
Published in Nature methods (01-09-2018)“…To understand human development and disease, as well as to regenerate damaged tissues, scientists are working to engineer certain cell types in vitro and to…”
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High-throughput single-cell transcriptomics on organoids
Published in Current opinion in biotechnology (01-02-2019)“…Three-dimensional (3D) tissues grown in culture from human stem cells offer the incredible opportunity to analyze and manipulate human development, and to…”
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Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program
Published in Nature neuroscience (01-07-2018)“…Ectopic expression of defined transcription factors can force direct cell-fate conversion from one lineage to another in the absence of cell division. Several…”
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Inferring and perturbing cell fate regulomes in human brain organoids
Published in Nature (London) (14-09-2023)“…Self-organizing neural organoids grown from pluripotent stem cells 1 – 3 combined with single-cell genomic technologies provide opportunities to examine gene…”
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Resolving Neurodevelopmental and Vision Disorders Using Organoid Single-Cell Multi-omics
Published in Neuron (Cambridge, Mass.) (23-09-2020)“…Human organoid models of the central nervous system, including the neural retina, are providing unprecedented opportunities to explore human neurodevelopment…”
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Human brain organoids influence rat behaviour
Published in Nature (London) (13-10-2022)“…Human tissue resembling the brain’s cortex can be grown from stem cells in vitro . Transplanting this tissue into a developing rat cortex enables it to mature,…”
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Several ways one goal—methanogenesis from unconventional substrates
Published in Applied microbiology and biotechnology (01-08-2020)“…Methane is the second most important greenhouse gas on earth. It is produced by methanogenic archaea, which play an important role in the global carbon cycle…”
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Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
Published in Proceedings of the National Academy of Sciences - PNAS (22-12-2015)“…Cerebral organoids—3D cultures of human cerebral tissue derived from pluripotent stem cells—have emerged as models of human cortical development. However, the…”
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Lineage recording in human cerebral organoids
Published in Nature methods (01-01-2022)“…Induced pluripotent stem cell (iPSC)-derived organoids provide models to study human organ development. Single-cell transcriptomics enable highly resolved…”
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Human organomics: a fresh approach to understanding human development using single-cell transcriptomics
Published in Development (Cambridge) (01-05-2017)“…Innovative methods designed to recapitulate human organogenesis from pluripotent stem cells provide a means to explore human developmental biology. New…”
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Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains
Published in Genome research (01-05-2020)“…Identification of gene expression traits unique to the human brain sheds light on the molecular mechanisms underlying human evolution. Here, we searched for…”
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The Organoid Cell Atlas
Published in Nature biotechnology (01-01-2021)Get full text
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What is a cell type?
Published in Science (American Association for the Advancement of Science) (18-08-2023)“…A next step for cell atlases should be to chart perturbations in human model systems International efforts are underway to provide a comprehensive survey of…”
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