Search Results - "Cammarata, Michael B"

Structural characterization of holo- and apo-myoglobin in the gas phase by ultraviolet photodissociation mass spectrometry by Cammarata, Michael B, Brodbelt, Jennifer S

“…Ultraviolet photodissociation (UVPD) mass spectrometry is employed to investigate the structure of holo-myoglobin as well as its apo form transferred to the…”
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ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair by Leung, Justin W C, Makharashvili, Nodar, Agarwal, Poonam, Chiu, Li-Ya, Pourpre, Renaud, Cammarata, Michael B, Cannon, Joe R, Sherker, Alana, Durocher, Daniel, Brodbelt, Jennifer S, Paull, Tanya T, Miller, Kyle M

“…Chromatin connects DNA damage response factors to sites of damaged DNA to promote the signaling and repair of DNA lesions. The histone H2A variants H2AX, H2AZ,…”
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Structural Characterization of Dihydrofolate Reductase Complexes by Top-Down Ultraviolet Photodissociation Mass Spectrometry by Cammarata, Michael B, Thyer, Ross, Rosenberg, Jake, Ellington, Andrew, Brodbelt, Jennifer S

“…The stepwise reduction of dihydrofolate to tetrahydrofolate entails significant conformational changes of dihydrofolate reductase (DHFR). Binary and ternary…”
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Tracking the Catalytic Cycle of Adenylate Kinase by Ultraviolet Photodissociation Mass Spectrometry by Mehaffey, M. Rachel, Cammarata, Michael B, Brodbelt, Jennifer S

“…The complex interplay of dynamic protein plasticity and specific side-chain interactions with substrate molecules that allows enzymes to catalyze reactions has…”
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UV-POSIT: Web-Based Tools for Rapid and Facile Structural Interpretation of Ultraviolet Photodissociation (UVPD) Mass Spectra by Rosenberg, Jake, Parker, W. Ryan, Cammarata, Michael B., Brodbelt, Jennifer S.

“…UV-POSIT (Ultraviolet Photodissociation Online Structure Interrogation Tools) is a suite of web-based tools designed to facilitate the rapid interpretation of…”
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Investigation of GTP-dependent dimerization of G12X K-Ras variants using ultraviolet photodissociation mass spectrometry by Mehaffey, M. Rachel, Schardon, Christopher L, Novelli, Elisa T, Cammarata, Michael B, Webb, Lauren J, Fast, Walter, Brodbelt, Jennifer S

“…Mutations in the GTPase enzyme K-Ras, specifically at codon G12, remain the most common genetic alterations in human cancers. The mechanisms governing…”
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Impact of G12 Mutations on the Structure of K‑Ras Probed by Ultraviolet Photodissociation Mass Spectrometry by Cammarata, Michael B, Schardon, Christopher L, Mehaffey, M. Rachel, Rosenberg, Jake, Singleton, Jonathan, Fast, Walter, Brodbelt, Jennifer S

“…Single-residue mutations at Gly12 (G12X) in the GTP-ase protein K-Ras can lead to activation of different downstream signaling pathways, depending on the…”
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Expanding the Scope of Cross-Link Identifications by Incorporating Collisional Activated Dissociation and Ultraviolet Photodissociation Methods by Cammarata, Michael B, Macias, Luis A, Rosenberg, Jake, Bolufer, Alexander, Brodbelt, Jennifer S

“…With the advent of new cross-linking chemistries, analytical technologies, and search algorithms, cross-linking has become an increasingly popular strategy for…”
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Ultraviolet Photodissociation for Characterization of Whole Proteins on a Chromatographic Time Scale by Cannon, Joe R, Cammarata, Michael B, Robotham, Scott A, Cotham, Victoria C, Shaw, Jared B, Fellers, Ryan T, Early, Bryan P, Thomas, Paul M, Kelleher, Neil L, Brodbelt, Jennifer S

“…Intact protein characterization using mass spectrometry thus far has been achieved at the cost of throughput. Presented here is the application of 193 nm…”
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Correction to “Structural Characterization of Dihydrofolate Reductase Complexes by Top-Down Ultraviolet Photodissociation Mass Spectrometry” by Cammarata, Michael B, Thyer, Ross, Rosenberg, Jake, Ellington, Andrew, Brodbelt, Jennifer S

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Peak parking determination of the obstruction factor in lauryl acrylate monolithic CEC columns by Anderson, Gwendolyn J., LaPier, Zoe, Cammarata, Michael B., Cullum, Tae Sun, Bushey, Michelle M.

“…The peak parking method was used to determine the obstruction factor of lauryl acrylate porous polymer monoliths. Polymers were prepared in situ in…”
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Expanding the Scope of Crosslink Identifications by Incorporating Collisional Activated Dissociation and Ultraviolet Photodissociation Methods by Cammarata, Michael B., Macias, Luis A., Rosenberg, Jake, Bolufer, Alexander, Brodbelt, Jennifer S.

“…With the advent of new crosslinking chemistries, analytical technologies, and search algorithms, crosslinking has become an increasingly popular strategy for…”
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Structural characterization of holo- and apo-myoglobin in the gas phase by ultraviolet photodissociation mass spectrometryElectronic supplementary information (ESI) available: ESI mass spectra of holo- and apo-myoglobin, schematic representation of holo-myoglobin, histograms of HCD and UVPD fragmentation yields of apo-myoglobin, B-factors and solvent accessibilities. See DOI: 10.1039/c4sc03200d by Cammarata, Michael B, Brodbelt, Jennifer S

“…Ultraviolet photodissociation (UVPD) mass spectrometry is employed to investigate the structure of holo-myoglobin as well as its apo form transferred to the…”
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Structural characterization of holo- and apo-myoglobin in the gas phase by ultraviolet photodissociation mass spectrometry† †Electronic supplementary information (ESI) available: ESI mass spectra of holo- and apo-myoglobin, schematic representation of holo-myoglobin, histograms of HCD and UVPD fragmentation yields of apo-myoglobin, B-factors and solvent accessibilities. See DOI: 10.1039/c4sc03200d Click here for additional data file by Cammarata, Michael B., Brodbelt, Jennifer S.

“…193 nm UV photodissociation of myoglobin in the gas phase showed preferential backbone cleavages in regions with higher relative B -factors. Ultraviolet…”
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Investigation of GTP-dependent dimerization of G12X K-Ras variants using ultraviolet photodissociation mass spectrometry† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc01032g by Mehaffey, M. Rachel, Schardon, Christopher L., Novelli, Elisa T., Cammarata, Michael B., Webb, Lauren J., Fast, Walter, Brodbelt, Jennifer S.

“…Variations in backbone cleavage efficiencies during UVPD-MS of G12X variants of K-Ras are used to relate mutation identity to structural changes that impact…”
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Characterization of Intra‐ and Intermolecular Protein Crosslinking by Top Down Ultraviolet Photodissociation Mass Spectrometry by Cammarata, Michael B., Brodbelt, Jennifer S.

“…Interactions within and between proteins impact structure and function, and mapping these interactions is a key hallmark of structural proteomics. One popular…”
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Appraisal of the Free Ulnar Flap Versatility in Craniofacial Soft-tissue Reconstruction by Kantar, Rami S., Rifkin, William J., Cammarata, Michael J., Jacoby, Adam, Farber, Scott J., Diaz-Siso, J. Rodrigo, Ceradini, Daniel J., Rodriguez, Eduardo D.

“…The unique anatomical characteristics of the forearm region make it especially popular as a free flap donor site for craniofacial soft-tissue reconstruction…”
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Abstract: Single-Stage Primary Cleft Lip and Palate Repair: Analysis of Early Complications by Kantar, Rami S., Cammarata, Michael J., Rifkin, William J., Maliha, Samantha G., Farber, Scott J., Diaz-Siso, J. Rodrigo, Flores, Roberto L.

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Abstract: Predictors of Adverse Outcomes in the Management of Mandibular Fractures: An Analysis of 953 Cases by Rifkin, William J., Daar, David A., Kantar, Rami S., Cammarata, Michael J., Wilson, Stelios C., Rodriguez, Eduardo D.

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Abstract 106: Impact of Diabetes On Microsurgical Free Tissue Transfer Outcomes: Analysis Of 6,030 Cases by Kantar, Rami S., Rifkin, William J., David, Joshua A., Cammarata, Michael J., Diaz-Siso, J. Rodrigo, Golas, Alyssa R., Levine, Jamie P., Ceradini, Daniel J.

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