Search Results - "Cammarata, Francesco"
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The Role of Hypoxia and SRC Tyrosine Kinase in Glioblastoma Invasiveness and Radioresistance
Published in Cancers (04-10-2020)“…Advances in functional imaging are supporting neurosurgery and radiotherapy for glioblastoma, which still remains the most aggressive brain tumor with poor…”
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2
Portrait of inflammatory response to ionizing radiation treatment
Published in Journal of inflammation (London, England) (18-02-2015)“…Ionizing radiation (IR) activates both pro-and anti-proliferative signal pathways producing an imbalance in cell fate decision. IR is able to regulate several…”
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3
SRC Tyrosine Kinase Inhibitor and X-rays Combined Effect on Glioblastoma Cell Lines
Published in International journal of molecular sciences (01-06-2020)“…Glioblastoma (GBM) is one of the most lethal types of tumor due to its high recurrence level in spite of aggressive treatment regimens involving surgery,…”
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4
Glut-3 Gene Knockdown as a Potential Strategy to Overcome Glioblastoma Radioresistance
Published in International journal of molecular sciences (01-02-2024)“…The hypoxic pattern of glioblastoma (GBM) is known to be a primary cause of radioresistance. Our study explored the possibility of using gene knockdown of key…”
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5
Nutraceutical Compounds as Sensitizers for Cancer Treatment in Radiation Therapy
Published in International journal of molecular sciences (23-10-2019)“…The improvement of diagnostic techniques and the efficacy of new therapies in clinical practice have allowed cancer patients to reach a higher chance to be…”
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6
The Hallmarks of Glioblastoma: Heterogeneity, Intercellular Crosstalk and Molecular Signature of Invasiveness and Progression
Published in Biomedicines (30-03-2022)“…In 2021 the World Health Organization published the fifth and latest version of the Central Nervous System tumors classification, which incorporates and…”
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7
Molecular Investigation on a Triple Negative Breast Cancer Xenograft Model Exposed to Proton Beams
Published in International journal of molecular sciences (01-09-2020)“…Specific breast cancer (BC) subtypes are associated with bad prognoses due to the absence of successful treatment plans. The triple-negative breast cancer…”
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8
Specific protein changes contribute to the differential muscle mass loss during ageing
Published in Proteomics (Weinheim) (01-02-2016)“…In the skeletal muscle, the ageing process is characterized by a loss of muscle mass and strength, coupled with a decline of mitochondrial function and a…”
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9
Proton Therapy and Src Family Kinase Inhibitor Combined Treatments on U87 Human Glioblastoma Multiforme Cell Line
Published in International journal of molecular sciences (24-09-2019)“…Glioblastoma Multiforme (GBM) is the most common of malignant gliomas in adults with an exiguous life expectancy. Standard treatments are not curative and the…”
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10
The Role of Radiation in Cancer Treatment: New Insights towards Personalized Therapies
Published in Journal of personalized medicine (19-02-2022)“…Despite all the recent pharmacological advances and the introduction of targeted therapies in clinical practice, cancer still remains one of the leading cause…”
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11
Radiation-Induced Gene Expression Changes in High and Low Grade Breast Cancer Cell Types
Published in International journal of molecular sciences (04-04-2018)“…There is extensive scientific evidence that radiation therapy (RT) is a crucial treatment, either alone or in combination with other treatment modalities, for…”
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12
Evaluation of proton beam radiation-induced skin injury in a murine model using a clinical SOBP
Published in PloS one (22-05-2020)“…The purpose of this paper is to characterize the skin deterministic damage due to the effect of proton beam irradiation in mice occurred during a long-term…”
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13
Microglia and glioblastoma heterocellular interplay sustains tumour growth and proliferation as an off‐target effect of radiotherapy
Published in Cell proliferation (01-06-2024)“…Glioblastoma (GBM), a WHO grade IV glioma, is a malignant primary brain tumour for which combination of surgery, chemotherapy and radiotherapy is the…”
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14
Proton-irradiated breast cells: molecular points of view
Published in Journal of radiation research (01-07-2019)“…Breast cancer (BC) is the most common cancer in women, highly heterogeneous at both the clinical and molecular level. Radiation therapy (RT) represents an…”
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15
Biological and Mechanical Characterization of the Random Positioning Machine (RPM) for Microgravity Simulations
Published in Life (Basel, Switzerland) (05-11-2021)“…The rapid improvement of space technologies is leading to the continuous increase of space missions that will soon bring humans back to the Moon and, in the…”
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16
Endoscopic Ultrasound to Identify the Actual Cause of Idiopathic Acute Pancreatitis: A Systematic Review
Published in Diagnostics (Basel) (01-10-2023)“…Idiopathic acute pancreatitis (IAP) presents a diagnostic challenge and refers to cases where the cause of acute pancreatitis remains uncertain despite a…”
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17
Radiation Gene-expression Signatures in Primary Breast Cancer Cells
Published in Anticancer research (01-05-2018)“…In breast cancer (BC) care, radiation therapy (RT) is an efficient treatment to control localized tumor. Radiobiological research is needed to understand…”
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18
Development of a portable hypoxia chamber for ultra-high dose rate laser-driven proton radiobiology applications
Published in Radiation oncology (London, England) (15-04-2022)“…There is currently significant interest in assessing the role of oxygen in the radiobiological effects at ultra-high dose rates. Oxygen modulation is…”
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High-dose Ionizing Radiation Regulates Gene Expression Changes in the MCF7 Breast Cancer Cell Line
Published in Anticancer research (01-05-2015)“…Intraoperative electron radiation therapy (IOERT) is a therapeutic technique which administers a single high dose of ionizing radiation immediately after…”
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20
Betula etnensis Raf. (Betulaceae) Extract Induced HO-1 Expression and Ferroptosis Cell Death in Human Colon Cancer Cells
Published in International journal of molecular sciences (03-06-2019)“…Raf. (Birch Etna) belonging to the Betulaceae family grows on the eastern slope of Etna. Many bioactive compounds present in Betula species are considered…”
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