Search Results - "Camm, Emily"

The Programming Power of the Placenta by Sferruzzi-Perri, Amanda N, Camm, Emily J

“…Size at birth is a critical determinant of life expectancy, and is dependent primarily on the placental supply of nutrients. However, the placenta is not just…”
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Developmental programming of cardiovascular dysfunction by prenatal hypoxia and oxidative stress by Giussani, Dino A, Camm, Emily J, Niu, Youguo, Richter, Hans G, Blanco, Carlos E, Gottschalk, Rachel, Blake, E Zachary, Horder, Katy A, Thakor, Avnesh S, Hansell, Jeremy A, Kane, Andrew D, Wooding, F B Peter, Cross, Christine M, Herrera, Emilio A

“…Fetal hypoxia is a common complication of pregnancy. It has been shown to programme cardiac and endothelial dysfunction in the offspring in adult life…”
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Age and an obesogenic diet affect mouse behaviour in a sex‐dependent manner by Mort, Emily J., Fordington, Surina, Heritage, Sophie, Fowden, Abigail L., Jones, Susan, Camm, Emily J.

“…Obesity is rising globally and is associated with neurodevelopmental and psychiatric disorders among children, adolescents and young adults. Whether obesity is…”
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Near to One's Heart: The Intimate Relationship Between the Placenta and Fetal Heart by Camm, Emily J, Botting, Kimberley J, Sferruzzi-Perri, Amanda N

“…The development of the fetal heart is exquisitely controlled by a multitude of factors, ranging from humoral to mechanical forces. The gatekeeper regulating…”
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Perinatal compromise affects development, form, and function of the hippocampus part one; clinical studies by White, Tegan A., Miller, Suzanne L., Sutherland, Amy E., Allison, Beth J., Camm, Emily J.

“…The hippocampus is a neuron-rich specialised brain structure that plays a central role in the regulation of emotions, learning and memory, cognition, spatial…”
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Diet‐induced maternal obesity impacts feto‐placental growth and induces sex‐specific alterations in placental morphology, mitochondrial bioenergetics, dynamics, lipid metabolism and oxidative stress in mice by Napso, Tina, Lean, Samantha C., Lu, Minhui, Mort, Emily J., Desforges, Michelle, Moghimi, Ali, Bartels, Beverly, El‐Bacha, Tatiana, Fowden, Abigail L., Camm, Emily J., Sferruzzi‐Perri, Amanda N.

“…Aim The current study investigated the impact of maternal obesity on placental phenotype in relation to fetal growth and sex. Methods Female C57BL6/J mice were…”
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Perinatal compromise affects development, form, and function of the hippocampus part two; preclinical studies by White, Tegan A., Miller, Suzanne L., Sutherland, Amy E., Allison, Beth J., Camm, Emily J.

“…The hippocampus is a vital brain structure deep in the medial temporal lobe that mediates a range of functions encompassing emotional regulation, learning,…”
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Placental Adaptation to Early-Onset Hypoxic Pregnancy and Mitochondria-Targeted Antioxidant Therapy in a Rodent Model by Nuzzo, Anna M., Camm, Emily J., Sferruzzi-Perri, Amanda N., Ashmore, Thomas J., Yung, Hong-wa, Cindrova-Davies, Tereza, Spiroski, Ana-Mishel, Sutherland, Megan R., Logan, Angela, Austin-Williams, Shani, Burton, Graham J., Rolfo, Alessandro, Todros, Tullia, Murphy, Michael P., Giussani, Dino A.

“…The placenta responds to adverse environmental conditions by adapting its capacity for substrate transfer to maintain fetal growth and development. Early-onset…”
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Cardiovascular and Cerebrovascular Implications of Growth Restriction: Mechanisms and Potential Treatments by Rock, Charmaine R., White, Tegan A., Piscopo, Beth R., Sutherland, Amy E., Miller, Suzanne L., Camm, Emily J., Allison, Beth J.

“…Fetal growth restriction (FGR) is a common complication of pregnancy, resulting in a fetus that fails to reach its genetically determined growth potential…”
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Vitamin C Prevents Intrauterine Programming of in vivo Cardiovascular Dysfunction in the Rat by Kane, Andrew D., Herrera, Emilio A., Camm, Emily J., Giussani, Dino A.

“…Background: Fetal hypoxia is common and in vitro evidence supports its role in the programming of adult cardiovascular dysfunction through the generation of…”
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Sex-Specific Effects of a Maternal Obesogenic Diet High in Fat and Sugar on Offspring Adiposity, Growth, and Behavior by Mort, Emily J, Heritage, Sophie, Jones, Susan, Fowden, Abigail L, Camm, Emily J

“…With rising rates of human obesity, this study aimed to determine the relationship between maternal diet-induced obesity, offspring morphometrics, and behavior…”
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In vivo mitochondria‐targeted protection against uterine artery vascular dysfunction and remodelling in rodent hypoxic pregnancy by Wang, Zhongchao, Camm, Emily J., Nuzzo, Anna Maria, Spiroski, Ana‐Mishel, Skeffington, Katie L., Ashmore, Thomas J., Rolfo, Alessandro, Todros, Tullia, Logan, Angela, Ma, Jin, Murphy, Michael P., Niu, Youguo, Giussani, Dino A.

“…Gestational hypoxia adversely affects uterine artery function, increasing complications. However, an effective therapy remains unidentified. Here, we show in…”
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Hypothyroidism impairs development of the gastrointestinal tract in the ovine fetus by Young, Rhian, Lewandowska, Dominika, Long, Emily, Wooding, F B Peter, De Blasio, Miles J, Davies, Katie L, Camm, Emily J, Sangild, Per T, Fowden, Abigail L, Forhead, Alison J

“…Growth and maturation of the fetal gastrointestinal tract near term prepares the offspring for the onset of enteral nutrition at birth. Structural and…”
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Maternal antioxidant treatment protects adult offspring against memory loss and hippocampal atrophy in a rodent model of developmental hypoxia by Camm, Emily J., Cross, Christine M., Kane, Andrew D., Tarry‐Adkins, Jane L., Ozanne, Susan E., Giussani, Dino A.

“…Chronic fetal hypoxia is one of the most common outcomes in complicated pregnancy in humans. Despite this, its effects on the long‐term health of the brain in…”
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Divergence of mechanistic pathways mediating cardiovascular aging and developmental programming of cardiovascular disease by Allison, Beth J., Kaandorp, Joepe J., Kane, Andrew D., Camm, Emily J., Lusby, Ciara, Cross, Christine M., Nevin‐Dolan, Rhianon, Thakor, Avnesh S., Derks, Jan B., Tarry‐Adkins, Jane L., Ozanne, Susan E., Giussani, Dino A.

“…Aging and developmental programming are both associated with oxidative stress and endothelial dysfunction, suggesting common mechanistic origins. However,…”
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Combined Statin and Glucocorticoid Therapy for the Safer Treatment of Preterm Birth by Kane, Andrew D., Herrera, Emilio A., Niu, Youguo, Camm, Emily J., Allison, Beth J., Tijsseling, Deodata, Lusby, Ciara, Derks, Jan B., Brain, Kirsty L., Bronckers, Inge M., Cross, Christine M., Berends, Lindsey, Giussani, Dino A.

“…Prematurity is strongly associated with poor respiratory function in the neonate. Rescue therapies include treatment with glucocorticoids due to their…”
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Mitochondria antioxidant protection against cardiovascular dysfunction programmed by early‐onset gestational hypoxia by Spiroski, Ana‐Mishel, Niu, Youguo, Nicholas, Lisa M., Austin‐Williams, Shani, Camm, Emily J., Sutherland, Megan R., Ashmore, Thomas J., Skeffington, Katie. L., Logan, Angela, Ozanne, Susan E., Murphy, Michael P., Giussani, Dino A.

“…Mitochondria‐derived oxidative stress during fetal development increases cardiovascular risk in adult offspring of pregnancies complicated by chronic fetal…”
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Chronic gestational hypoxia accelerates ovarian aging and lowers ovarian reserve in next‐generation adult rats by Aiken, Catherine E., Tarry-Adkins, Jane L., Spiroski, Ana-Mishel, Nuzzo, Anna M., Ashmore, Thomas J., Rolfo, Alessandro, Sutherland, Megan J., Camm, Emily J., Giussani, Dino A., Ozanne, Susan E.

“…ABSTRACT Chronic fetal hypoxia is a common complication observed in human pregnancy, impacting pregnancies across global contexts. Exposure to chronic…”
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Development of cerebral mitochondrial respiratory function is impaired by thyroid hormone deficiency before birth in a region‐specific manner by Davies, Katie L., Smith, Danielle J., El‐Bacha, Tatiana, Stewart, Max E., Easwaran, Akshay, Wooding, Peter F. P., Forhead, Alison J., Murray, Andrew J., Fowden, Abigail L., Camm, Emily J.

“…Thyroid hormones regulate adult metabolism partly through actions on mitochondrial oxidative phosphorylation (OXPHOS). They also affect neurological…”
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Thyroid Hormone Deficiency Suppresses Fetal Pituitary-Adrenal Function Near Term: Implications for the Control of Fetal Maturation and Parturition by Camm, Emily J, Inzani, Isabella, De Blasio, Miles J, Davies, Katie L, Lloyd, India R, Wooding, F B Peter, Blache, Dominique, Fowden, Abigail L, Forhead, Alison J

“…The fetal hypothalamic-pituitary-adrenal (HPA) axis plays a key role in the control of parturition and maturation of organ systems in preparation for birth. In…”
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