Search Results - "Cameron Falkner, K."

Nuclear receptors and nonalcoholic fatty liver disease by Cave, Matthew C, Clair, Heather B, Hardesty, Josiah E, Falkner, K Cameron, Feng, Wenke, Clark, Barbara J, Sidey, Jennifer, Shi, Hongxue, Aqel, Bashar A, McClain, Craig J, Prough, Russell A

“…Nuclear receptors are transcription factors which sense changing environmental or hormonal signals and effect transcriptional changes to regulate core life…”
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Keratin 18 Is a Diagnostic and Prognostic Factor for Acute Alcoholic Hepatitis by Vatsalya, Vatsalya, Cave, Matthew C., Kong, Maiying, Gobejishvili, Leila, Falkner, K. Cameron, Craycroft, John, Mitchell, Mack, Szabo, Gyongi, McCullough, Arthur, Dasarathy, Srinivasan, Radaeva, Svetlana, Barton, Bruce, McClain, Craig J.

“…Acute alcoholic hepatitis (AAH) is a major cause of liver-related morbidity and mortality; there are no good blood biomarkers for diagnosis or determining…”
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Human receptor activation by aroclor 1260, a polychlorinated biphenyl mixture by Wahlang, Banrida, Falkner, K Cameron, Clair, Heather B, Al-Eryani, Laila, Prough, Russell A, States, J Christopher, Coslo, Denise M, Omiecinski, Curtis J, Cave, Matthew C

“…Polychlorinated biphenyls (PCBs) are persistent environmental toxicants, present in 100% of U.S. adults and dose-dependently associated with obesity and…”
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Insecticide and metal exposures are associated with a surrogate biomarker for non-alcoholic fatty liver disease in the National Health and Nutrition Examination Survey 2003–2004 by Wahlang, Banrida, Appana, Savitri, Falkner, K. Cameron, McClain, Craig J., Brock, Guy, Cave, Matthew C.

“…Non-alcoholic fatty liver disease (NAFLD), the most common form of liver disease, affects over 30% of the US population. Our group and others have previously…”
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Polychlorinated Biphenyl-Xenobiotic Nuclear Receptor Interactions Regulate Energy Metabolism, Behavior, and Inflammation in Non-alcoholic-Steatohepatitis by Wahlang, Banrida, Prough, Russell A, Falkner, K Cameron, Hardesty, Josiah E, Song, Ming, Clair, Heather B, Clark, Barbara J, States, J Christopher, Arteel, Gavin E, Cave, Matthew C

“…Polychlorinated biphenyls (PCBs) are environmental pollutants associated with non-alcoholic-steatohepatitis (NASH), diabetes, and obesity. We previously…”
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Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease by Wahlang, Banrida, Song, Ming, Beier, Juliane I., Cameron Falkner, K., Al-Eryani, Laila, Clair, Heather B., Prough, Russell A., Osborne, Tanasa S., Malarkey, David E., States, J. Christopher, Cave, Matthew C.

“…Polychlorinated biphenyls (PCBs) are persistent organic pollutants associated with non-alcoholic fatty liver disease (NAFLD) in epidemiologic studies. The…”
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Dioxin-like and non-dioxin-like PCBs differentially regulate the hepatic proteome and modify diet-induced nonalcoholic fatty liver disease severity by Jin, Jian, Wahlang, Banrida, Shi, Hongxue, Hardesty, Josiah E., Falkner, K. Cameron, Head, Kimberly Z., Srivastava, Sudhir, Merchant, Michael L., Rai, Shesh N., Cave, Matthew C., Prough, Russell A.

“…Polychlorinated biphenyls (PCBs) are persistent organic pollutants associated with metabolic disruption and nonalcoholic fatty liver disease (NAFLD). Based on…”
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Olanzapine activates hepatic mammalian target of rapamycin: new mechanistic insight into metabolic dysregulation with atypical antipsychotic drugs by Schmidt, Robin H, Jokinen, Jenny D, Massey, Veronica L, Falkner, K Cameron, Shi, Xue, Yin, Xinmin, Zhang, Xiang, Beier, Juliane I, Arteel, Gavin E

“…Olanzapine (OLZ), an effective treatment of schizophrenia and other disorders, causes weight gain and metabolic syndrome. Most studies to date have focused on…”
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Concentration dependence of human and mouse aryl hydrocarbon receptor responsiveness to polychlorinated biphenyl exposures: Implications for aroclor mixtures by Shi, Hongxue, Hardesty, Josiah E., Jin, Jian, Head, Kimberly Z., Falkner, K. Cameron, Cave, Matthew C., Prough, Russell Allen

“…1. Aryl hydrocarbon receptor (AhR) ligands, including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs), are endocrine disrupting…”
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Metabolomic Analysis of the Effects of Polychlorinated Biphenyls in Nonalcoholic Fatty Liver Disease by Shi, Xue, Wahlang, Banrida, Wei, Xiaoli, Yin, Xinmin, Falkner, K. Cameron, Prough, Russell A, Kim, Seong Ho, Mueller, Eugene G, McClain, Craig J, Cave, Matthew, Zhang, Xiang

“…Polychlorinated biphenyls (PCBs) are persistent organic pollutants and have been associated with abnormal liver enzymes and suspected nonalcoholic fatty liver…”
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Polychlorinated biphenyl 153 is a diet-dependent obesogen that worsens nonalcoholic fatty liver disease in male C57BL6/J mice by Wahlang, Banrida, Falkner, K. Cameron, Gregory, Bonnie, Ansert, Douglas, Young, David, Conklin, Daniel J, Bhatnagar, Aruni, McClain, Craig J, Cave, Matt

“…Polychlorinated biphenyls (PCBs) are persistent environmental pollutants that are detectable in the serum of all American adults. Amongst PCB congeners, PCB…”
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Polychlorinated biphenyl exposures differentially regulate hepatic metabolism and pancreatic function: Implications for nonalcoholic steatohepatitis and diabetes by Shi, Hongxue, Jan, Jian, Hardesty, Josiah E., Falkner, K. Cameron, Prough, Russell A., Balamurugan, Appakalai N., Mokshagundam, Sri Prakash, Chari, Suresh T., Cave, Matthew C.

“…The endocrine disrupting chemicals, polychlorinated biphenyls (PCBs), have been associated with nonalcoholic steatohepatitis (NASH) and diabetes. However, an…”
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Toxicant-associated Steatohepatitis by Wahlang, Banrida, Beier, Juliane I., Clair, Heather B., Bellis-Jones, Heather J., Falkner, K. Cameron, McClain, Craig J., Cave, Matt C.

“…Hepatotoxicity is the most common organ injury due to occupational and environmental exposures to industrial chemicals. A wide range of liver pathologies…”
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Mechanisms of Environmental Contributions to Fatty Liver Disease by Wahlang, Banrida, Jin, Jian, Beier, Juliane I., Hardesty, Josiah E., Daly, Erica F., Schnegelberger, Regina D., Falkner, K. Cameron, Prough, Russell A., Kirpich, Irina A, Cave, Matthew C.

“…Purpose Fatty liver disease (FLD) affects over 25% of the global population and may lead to liver-related mortality due to cirrhosis and liver cancer. FLD…”
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Identifying sex differences arising from polychlorinated biphenyl exposures in toxicant-associated liver disease by Wahlang, Banrida, Jin, Jian, Hardesty, Josiah E., Head, Kimberly Z., Shi, Hongxue, Falkner, K. Cameron, Prough, Russell A., Klinge, Carolyn M., Cave, Matthew C.

“…Exposures to persistent environmental pollutants like polychlorinated biphenyls (PCBs) has been associated with liver diseases such as toxicant-associated…”
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Regulation of the Rat Glutathione S-Transferase A2 Gene by Glucocorticoids: Crosstalk Through C EBPs by Cameron Falkner, K., Prough, Russell A.

“…Regulation of the rat glutathione S-transferase A2 (GSTA2) gene by glucocorticoids is biphasic in its concentration dependence to glucocorticoids, with…”
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Epidermal Growth Factor Receptor Signaling Disruption by Endocrine and Metabolic Disrupting Chemicals by Hardesty, Josiah E, Al-Eryani, Laila, Wahlang, Banrida, Falkner, K Cameron, Shi, Hongxue, Jin, Jian, Vivace, Brad J, Ceresa, Brian P, Prough, Russell A, Cave, Matthew C

“…Abstract The purpose of this study is to identify an environmentally relevant shared receptor target for endocrine and metabolism disrupting chemical…”
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Occupational exposures at a polyvinyl chloride production facility are associated with significant changes to the plasma metabolome by Guardiola, John J., Beier, Juliane I., Falkner, K. Cameron, Wheeler, Benjamin, McClain, Craig James, Cave, Matt

“…Occupational vinyl chloride (VC) exposures have been associated with toxicant-associated steatohepatitis and liver cancer. Metabolomics has been used to…”
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Hepatic signalling disruption by pollutant Polychlorinated biphenyls in steatohepatitis by Hardesty, Josiah E., Wahlang, Banrida, Falkner, K. Cameron, Shi, Hongxue, Jin, Jian, Wilkey, Daniel, Merchant, Michael, Watson, Corey, Prough, Russell A., Cave, Matthew C.

“…Polychlorinated biphenyl-mediated steatohepatitis has been shown to be due in part to inhibition of epidermal growth factor receptor (EGFR) signalling. EGFR…”
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Proteomic Analysis Reveals Novel Mechanisms by Which Polychlorinated Biphenyls Compromise the Liver Promoting Diet-Induced Steatohepatitis by Hardesty, Josiah E, Wahlang, Banrida, Falkner, K. Cameron, Shi, Hongxue, Jin, Jian, Zhou, Yun, Wilkey, Daniel W, Merchant, Michael L, Watson, Corey T, Feng, Wenke, Morris, Andrew J, Hennig, Bernhard, Prough, Russell A, Cave, Matthew C

“…Environmental pollution contributes to fatty liver disease pathogenesis. Polychlorinated biphenyl (PCB) exposures have been associated with liver enzyme…”
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