Search Results - "Cameron, Fraser"

Piercing issue: a 10-year single-centre experience of magnet ingestion in children by John, Michael, Stern, Guy, Cameron, Fraser, Peeraully, Riyad, Shenoy, Manoj

“…Correspondence to Michael John, Dept of Paediatric Surgery, Queen's Medical Centre, Nottingham NG7 2UH, UK; mpjohn82@gmail.com Accidental ingestion of one or…”
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Inflammation and MiR-21 pathways functionally interact to downregulate PDCD4 in colorectal cancer by Peacock, Oliver, Lee, Andrew C, Cameron, Fraser, Tarbox, Rebecca, Vafadar-Isfahani, Natasha, Tufarelli, Cristina, Lund, Jonathan N

“…Inflammation plays a direct role in colorectal cancer (CRC) progression; however the molecular mechanisms responsible for this effect are unclear. The…”
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Exploiting endogenous and therapy-induced apoptotic vulnerabilities in immunoglobulin light chain amyloidosis with BH3 mimetics by Fraser, Cameron S., Spetz, Johan K. E., Qin, Xingping, Presser, Adam, Choiniere, Jonathan, Li, Chendi, Yu, Stacey, Blevins, Frances, Hata, Aaron N., Miller, Jeffrey W., Bradshaw, Gary A., Kalocsay, Marian, Sanchorawala, Vaishali, Sarosiek, Shayna, Sarosiek, Kristopher A.

“…Immunoglobulin light chain (AL) amyloidosis is an incurable hematologic disorder typically characterized by the production of amyloidogenic light chains by…”
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Predictive Low-Glucose Insulin Suspension Reduces Duration of Nocturnal Hypoglycemia in Children Without Increasing Ketosis by Buckingham, Bruce A, Raghinaru, Dan, Cameron, Fraser, Bequette, B Wayne, Chase, H Peter, Maahs, David M, Slover, Robert, Wadwa, R Paul, Wilson, Darrell M, Ly, Trang, Aye, Tandy, Hramiak, Irene, Clarson, Cheril, Stein, Robert, Gallego, Patricia H, Lum, John, Sibayan, Judy, Kollman, Craig, Beck, Roy W

“…Nocturnal hypoglycemia can cause seizures and is a major impediment to tight glycemic control, especially in young children with type 1 diabetes. We conducted…”
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A Randomized Trial of a Home System to Reduce Nocturnal Hypoglycemia in Type 1 Diabetes by MAAHS, David M, CALHOUN, Peter, SLOVER, Robert, PAUL WADWA, R, WILSON, Darrell M, KOLLMAN, Craig, BECK, Roy W, BUCKINGHAM, Bruce A, PETER CHASE, H, HRAMIAK, Irene, LUM, John, CAMERON, Fraser, WAYNE BEQUETTE, B, AYE, Tandy, PAUL, Terri

“…Overnight hypoglycemia occurs frequently in individuals with type 1 diabetes and can result in loss of consciousness, seizure, or even death. We conducted an…”
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Naïve T-cell decline is a significant contributor to expression changes in ageing blood by Fraser, Cameron, Owen, Brady M

“…No clear consensus has emerged from the literature on the gene expression changes that occur in human whole blood with age. In this study we compared whole…”
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Functional genomic screens with death rate analyses reveal mechanisms of drug action by Honeywell, Megan E., Isidor, Marie S., Harper, Nicholas W., Fontana, Rachel E., Birdsall, Gavin A., Cruz-Gordillo, Peter, Porto, Sydney A., Jerome, Madison, Fraser, Cameron S., Sarosiek, Kristopher A., Guertin, David A., Spinelli, Jessica B., Lee, Michael J.

“…A common approach for understanding how drugs induce their therapeutic effects is to identify the genetic determinants of drug sensitivity. Because…”
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Lymphatic system regulation of anti-cancer immunity and metastasis by Lei, Pin-Ji, Fraser, Cameron, Jones, Dennis, Ubellacker, Jessalyn M, Padera, Timothy P

“…Cancer dissemination to lymph nodes (LN) is associated with a worse prognosis, increased incidence of distant metastases and reduced response to therapy. The…”
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A hyperparameter consensus method for agreement under uncertainty by Fraser, Cameron S.R., Bertuccelli, Luca F., Choi, Han-Lim, How, Jonathan P.

“…This paper addresses the problem of information consensus in a team of networked agents by presenting a generic consensus method that permits agreement to a…”
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Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapy-induced toxicities by Spetz, Johan K E, Florido, Mary H C, Fraser, Cameron S, Qin, Xingping, Choiniere, Jonathan, Yu, Stacey J, Singh, Rumani, Friesen, Max, Rubin, Lee L, Salem, Joe-Elie, Moslehi, Javid J, Sarosiek, Kristopher A

“…Although major organ toxicities frequently arise in patients treated with cytotoxic or targeted cancer therapies, the mechanisms that drive them are poorly…”
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Evaluation of quantitative biomarkers of aging in human PBMCs by Owen, Brady M., Phie, James, Huynh, Jennifer, Needham, Scott, Fraser, Cameron

“…Functional decline with age contributes significantly to the burden of disease in developed countries. There is growing interest in the development of…”
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Cells from the adult corneal stroma can be reprogrammed to a neuron-like cell using exogenous growth factors by Greene, Carol Ann, Chang, Chuan-Yuan, Fraser, Cameron J., Nelidova, Dasha E., Chen, Jing A., Lim, Angela, Brebner, Alex, McGhee, Jennifer, Sherwin, Trevor, Green, Colin R.

“…Cells thought to be stem cells isolated from the cornea of the eye have been shown to exhibit neurogenic potential. We set out to uncover the identity and…”
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Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex by McNamara, Molly C., Hosios, Aaron M., Torrence, Margaret E., Zhao, Ting, Fraser, Cameron, Wilkinson, Meghan, Kwiatkowski, David J., Henske, Elizabeth P., Wu, Chin-Lee, Sarosiek, Kristopher A., Valvezan, Alexander J., Manning, Brendan D.

“…mTORC1 is aberrantly activated in cancer and in the genetic tumor syndrome tuberous sclerosis complex (TSC), which is caused by loss-of-function mutations in…”
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Italy's foreign policy in the twenty-first century : a contested nature?/National leaders and the making of Europe : key episodes in the life of the European Council/The trajectory of Iran's nuclear program/Security and defensive democracy in Israel : a critical approach to political discourse/The Syrian Jihad : Al-Qaeda, the Islamic State and the evolution of an insurgency/Mercenaries, hybrid armies and national security : private soldiers and the state in the 21st century by Badde, Francesco Jonas, Cameron, Fraser, Zunino, Greta, Capranelli, Valeria, Garnero, Matteo, Cecinini, Sofia

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EU-Asia should defend multilateralism by Cameron, Fraser

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BH3 Profiling: A Functional Assay to Measure Apoptotic Priming and Dependencies by Fraser, Cameron, Ryan, Jeremy, Sarosiek, Kristopher

“…Apoptosis (programmed cell death) is activated by a wide variety of cellular stresses or insults and is vital for proper mammalian development as well as the…”
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After Iraq: The EU and Global Governance by Cameron, Fraser

“…Cameron suggests that the draft constitutional treaty produced by the Convention on the Future of Europe provides only a shaky basis for a coherent external…”
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Towards an EU Strategic Concept by Cameron, Fraser

“…The article 'Towards an EU Strategic Concept' examines the state of the EU's foreign and security policy after the Iraq war and after publication of both the…”
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A Model for the Performance Evaluation of Packet Transmissions Using Type-II Hybrid ARQ over a Correlated Error Channel by Mukhtar, Rami, Hanly, Stephen, Zukerman, Moshe, Fraser, Cameron

“…Type-II Hybrid-ARQ (Type-II HARQ) has been shown, under certain circumstances, to increase the efficiency and reduce loss of data transmissions over a wireless…”
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Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics by Sarosiek, Kristopher A., Fraser, Cameron, Muthalagu, Nathiya, Bhola, Patrick D., Chang, Weiting, McBrayer, Samuel K., Cantlon, Adam, Fisch, Sudeshna, Golomb-Mello, Gail, Ryan, Jeremy A., Deng, Jing, Jian, Brian, Corbett, Chris, Goldenberg, Marti, Madsen, Joseph R., Liao, Ronglih, Walsh, Dominic, Sedivy, John, Murphy, Daniel J., Carrasco, Daniel Ruben, Robinson, Shenandoah, Moslehi, Javid, Letai, Anthony

“…It is not understood why healthy tissues can exhibit varying levels of sensitivity to the same toxic stimuli. Using BH3 profiling, we find that mitochondria of…”
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