Nail lichen striatus: Clinical features and long-term follow-up of five patients

Nail involvement in lichen striatus (LS) is uncommon and has always been reported in association with typical skin lesions. We attempted to characterize the clinical and pathologic features and the long-term prognosis of nail LS. Five cases of LS of the nail including three cases with exclusive nail...

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Bibliographic Details
Published in:	Journal of the American Academy of Dermatology Vol. 36; no. 6; pp. 908 - 913
Main Authors:	Tosti, Antonella, Peluso, Anna Maria, Misciali, Cosimo, Cameli, Nortna
Format:	Journal Article
Language:	English
Published:	New York, NY Mosby, Inc 01-06-1997 Elsevier
Subjects:	Adolescent Adult Biological and medical sciences Child Dermatology Female Follow-Up Studies Foot Dermatoses - complications Foot Dermatoses - pathology Hand Dermatoses - complications Hand Dermatoses - pathology Humans Lichenoid Eruptions - complications Lichenoid Eruptions - pathology Male Medical sciences Nail Diseases - complications Nail Diseases - pathology Nails - pathology Psoriasis. Parapsoriasis. Lichen Case study Human Nail disease Skin disease Nail(anatomy) Lichen striatus
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Summary:	Nail involvement in lichen striatus (LS) is uncommon and has always been reported in association with typical skin lesions. We attempted to characterize the clinical and pathologic features and the long-term prognosis of nail LS. Five cases of LS of the nail including three cases with exclusive nail involvement were evaluated and the literature reviewed. Biopsy specimens showed a moderately dense bandlike lymphohistiocytic infiltrate affecting the proximal nailfold, the nail bed, and the nail matrix dermis. Exocytosis with slight spongiosis, focal hypergranulosis, and dyskeratotic cells were detectable in the nail matrix epithelium. Spontaneous regression of the onychodystrophy occurred after 4 to 12 months from the time of diagnosis (mean, 8.4 months). Nail LS is not necessarily associated with skin lesions but can also be an isolated finding. The diagnosis of nail LS should be strongly suspected when a child or a young patient presents with lichen planus-like nail abnormalities localized to the lateral or medial portion of a single nail.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	0190-9622 1097-6787
DOI:	10.1016/S0190-9622(97)80270-8