Search Results - "Cambon‐Thomsen, A"

Implementing Pharmacogenomics in Europe: Design and Implementation Strategy of the Ubiquitous Pharmacogenomics Consortium by van der Wouden, CH, Cambon‐Thomsen, A, Cecchin, E, Cheung, KC, Dávila‐Fajardo, CL, Deneer, VH, Dolžan, V, Ingelman‐Sundberg, M, Jönsson, S, Karlsson, MO, Kriek, M, Mitropoulou, C, Patrinos, GP, Pirmohamed, M, Samwald, M, Schaeffeler, E, Schwab, M, Steinberger, D, Stingl, J, Sunder‐Plassmann, G, Toffoli, G, Turner, RM, van Rhenen, MH, Swen, JJ, Guchelaar, H‐J

“…Despite scientific and clinical advances in the field of pharmacogenomics (PGx), application into routine care remains limited. Opportunely, several…”
Get full text

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus by Bouzekri, N, Pritchard, L.E, Undlien, D.E, Pociot, F, Merriman, M.E, Bennett, S.T, Kawaguchi, Y, Bain, S.C, Cambon-Thomsen, A, Barnett, A.H, Powell, E.E, Todd, J.A, Nerup, J, Gough, S.C.L, Dronsfield, M.J, Rønningen, K.S, Lucassen, A.M

“…The IDDM2 locus encoding susceptibility to type 1 diabetes was mapped previously to a 4.1-kb region spanning the insulin gene and a minisatellite or variable…”
Get full text

Trends in ethical and legal frameworks for the use of human biobanks by Cambon-Thomsen, A, Rial-Sebbag, E, Knoppers, B. M

“…Numerous studies of genetic epidemiology and post-genomics in respiratory diseases rely on the use of biobanks, defined as organised biological sample…”
Get full text

Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome llq by Hashimoto, L, Habita, C, Beressi, J. P, Delepine, M, Basse, C, Cambon-Thomsen, A, Deschamps, I, Rotter, J. I, Djoulah, S, James, M. R, Froguel, P, Weissenbach, J, Lathrop, G. M, Julier, C

Get full text

International transfers of personal data for health research following Schrems II: a problem in need of a solution by Hallinan, Dara, Bernier, Alexander, Cambon-Thomsen, Anne, Crawley, Francis P, Dimitrova, Diana, Medeiros, Claudia Bauzer, Nilsonne, Gustav, Parker, Simon, Pickering, Brian, Rennes, Stéphanie

“…On 16 July 2020, the Court of Justice of the European Union issued their decision in the Schrems II case concerning Facebook's transfers of personal data from…”
Get full text

Linkage disequilibrium and haplotype blocks in the MHC vary in an HLA haplotype specific manner assessed mainly by DRB103 and DRB104 haplotypes by Blomhoff, A, Olsson, M, Johansson, S, Akselsen, H E, Pociot, F, Nerup, J, Kockum, I, Cambon-Thomsen, A, Thorsby, E, Undlien, D E, Lie, B A

“…First generation linkage disequilibrium (LD) and haplotype maps of the human major histocompatibility complex (MHC) have been generated in order to aid the…”
Get full text

Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story Mechanisms of the Development of ALLergy; EUFP7-CP-IP; Project No: 261357; 2010-2015 by Bousquet, J, Anto, JM, Akdis, M, Auffray, C, Keil, T, Momas, I, Postma, DS, Valenta, R, Wickman, M, Cambon-Thomsen, A

Get full text

MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine by Bousquet, J., Anto, J., Auffray, C., Akdis, M., Cambon‐Thomsen, A., Keil, T., Haahtela, T., Lambrecht, B. N., Postma, D. S., Sunyer, J., Valenta, R., Akdis, C. A., Annesi‐Maesano, I., Arno, A., Bachert, C., Ballester, F., Basagana, X., Baumgartner, U., Bindslev‐Jensen, C., Brunekreef, B., Carlsen, K. H., Chatzi, L., Crameri, R., Eveno, E., Forastiere, F., Garcia‐Aymerich, J., Guerra, S., Hammad, H., Heinrich, J., Hirsch, D., Jacquemin, B., Kauffmann, F., Kerkhof, M., Kogevinas, M., Koppelman, G. H., Kowalski, M. L., Lau, S., Lodrup‐Carlsen, K. C., Lopez‐Botet, M., Lotvall, J., Lupinek, C., Maier, D., Makela, M. J., Martinez, F. D., Mestres, J., Momas, I., Nawijn, M. C., Neubauer, A., Oddie, S., Palkonen, S., Pin, I., Pison, C., Rancé, F., Reitamo, S., Rial‐Sebbag, E., Salapatas, M., Siroux, V., Smagghe, D., Torrent, M., Toskala, E., van Cauwenberge, P., van Oosterhout, A. J. M., Varraso, R., von Hertzen, L., Wickman, M., Wijmenga, C., Worm, M., Wright, J., Zuberbier, T.

“…To cite this article: Bousquet J, Anto J, Auffray C, Akdis M, Cambon‐Thomsen A, Keil T, Haahtela T, Lambrecht BN, Postma DS, Sunyer J, Valenta R, Akdis CA,…”
Get full text

Genetic diversity in the Iberian Peninsula determined from mitochondrial sequence analysis by Côrte-Real, H B, Macaulay, V A, Richards, M B, Hariti, G, Issad, M S, Cambon-Thomsen, A, Papiha, S, Bertranpetit, J, Sykes, B C

“…We have analysed 302 bp of the first hypervariable region of the mitochondrial D-loop in 271 individuals from different regions of the Iberian Peninsula and 85…”
Get more information

Biobanking for Europe by Yuille, Martin, van Ommen, Gert-Jan, Bréchot, Christian, Cambon-Thomsen, Anne, Dagher, Georges, Landegren, Ulf, Litton, Jan-Eric, Pasterk, Markus, Peltonen, Leena, Taussig, Mike, Wichmann, H-Erich, Zatloukal, Kurt

“…Biobanks are well-organized resources comprising biological samples and associated information that are accessible to scientific investigation. Across Europe,…”
Get full text

Interferon gamma gene polymorphism and susceptibility to, and severity of, rheumatoid arthritis by Constantin, A, Navaux, F, Lauwers-Cancès, V, Abbal, M, van Meerwijk, JPM, Mazières, B, Cambon-Thomsen, A, Cantagrel, A

“…A strong association between an interferon gamma (IFN-γ) gene polymorphism and rheumatoid arthritis susceptibility and severity has been reported in a…”
Get full text

CORRIGENDUM: Implementing Pharmacogenomics in Europe: Design and Implementation Strategy of the Ubiquitous Pharmacogenomics Consortium by van der Wouden, CH, Cambon‐Thomsen, A, Cecchin, E, Cheung, KC, Dávila‐Fajardo, CL, Deneer, VH, Dolžan, V, Ingelman‐Sundberg, M, Jönsson, S, Karlsson, MO, Kriek, M, Mitropoulou, C, Patrinos, GP, Pirmohamed, M, Samwald, M, Schaeffeler, E, Schwab, M, Steinberger, D, Stingl, J, Sunder‐Plassmann, G, Toffoli, G, Turner, RM, van Rhenen, MH, Swen, JJ, Guchelaar, H‐J

Get full text

Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex by Viken, M K, Blomhoff, A, Olsson, M, Akselsen, H E, Pociot, F, Nerup, J, Kockum, I, Cambon-Thomsen, A, Thorsby, E, Undlien, D E, Lie, B A

“…The high-risk human leukocyte antigen ( HLA ) -DRB1 , DQA1 and DQB1 alleles cannot explain the entire type 1 diabetes (T1D) association observed within the…”
Get full text

Association between RANK, RANKL and OPG polymorphisms with ACPA and erosions in rheumatoid arthritis: results from a meta-analysis involving three French cohorts by Ruyssen-Witrand, Adeline, Degboé, Yannick, Cantagrel, A, Nigon, D, Lukas, C, Scaramuzzino, S, Allanore, Y, Vittecoq, O, Schaeverbeke, T, Morel, J, Sibilia, J, Cambon-Thomsen, A, Dieudé, P, Constantin, A

“…The RANK/RANKL/osteoprotegerin (OPG) system plays a central role in the pathogenesis of bone erosions in rheumatoid arthritis (RA). The aim of this study was…”
Get full text

New insights into the genetics of immune responses in rheumatoid arthritis by Ruyssen-Witrand, A., Constantin, A., Cambon-Thomsen, A., Thomsen, M.

“…Rheumatoid arthritis (RA) is a common autoimmune disease with a strong genetic component. Numerous aberrant immune responses have been described during the…”
Get full text

The ethical introduction of genome-based information and technologies into public health by Howard, H C, Swinnen, E, Douw, K, Vondeling, H, Cassiman, J-J, Cambon-Thomsen, A, Borry, P

“…With the human genome project running from 1989 until its completion in 2003, and the incredible advances in sequencing technology and in bioinformatics during…”
Get more information

Evidence of at least two type 1 diabetes susceptibility genes in the HLA complex distinct from HLA-DQB1, -DQA1 and -DRB1 by JOHANSSON, S, LIE, B. A, TODD, J. A, POCIOT, F, NERUP, J, CAMBON-THOMSEN, A, KOCKUM, I, AKSELSEN, H. E, THORSBY, E, UNDLIEN, D. E

“…Susceptibility to, and protection against development of type 1 diabetes (T1D) are primarily associated with the highly polymorphic exon 2 sequences of the HLA…”
Get full text

Navigating the perfect [data] storm by Murtagh, M.J., Thorisson, G.A., Wallace, S.E., Kaye, J., Demir, I., Fortier, I., Harris, J.R., Cox, D., Deschênes, M., Laflamme, P., Ferretti, V., Sheehan, N.A., Hudson, T.J., Thomsen, A. Cambon, Stolk, R.P., Knoppers, B.M., Brookes, A.J., Burton, P.R.

“…Bioscience has recently undergone a series of knowledge-based and technological revolutions. A critical consequence has been increasing recognition of the need…”
Get full text

Recombination fractions in the HLA system based on the data set 'provinces Françaises': indications of haplotype-specific recombination rates by Thomsen, M, Neugebauer, M, Arnaud, J, Borot, N, Sevin, A, Baur, M, Cambon-Thomsen, A

“…In the large genetic survey "Provinces Françaises' the recombination fractions in the HLA system have been estimated by a family analysis programme (FAP). A…”
Get more information

Integration of microsatellite characteristics in the MHC region: a literature and sequence based analysis by Gourraud, P.A., Mano, S., Barnetche, T., Carrington, M., Inoko, H., Cambon-Thomsen, A.

“…:  Reviews of microsatellite markers in the human leukocyte antigen region have been very useful in addressing the needs of the immunogenetics community…”
Get full text