Search Results - "Camara, Niels OS"

Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice by Caricilli, Andréa M, Picardi, Paty K, de Abreu, Lélia L, Ueno, Mirian, Prada, Patrícia O, Ropelle, Eduardo R, Hirabara, Sandro Massao, Castoldi, Ângela, Vieira, Pedro, Camara, Niels O S, Curi, Rui, Carvalheira, José B, Saad, Mário J A

“…Environmental factors and host genetics interact to control the gut microbiota, which may have a role in the development of obesity and insulin resistance…”
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Leptin deficiency impairs maturation of dendritic cells and enhances induction of regulatory T and Th17 cells by Moraes‐Vieira, Pedro M.M., Larocca, Rafael A., Bassi, Enio J., Peron, Jean Pierre S., Andrade‐Oliveira, Vinícius, Wasinski, Frederick, Araujo, Ronaldo, Thornley, Thomas, Quintana, Francisco J., Basso, Alexandre S., Strom, Terry B., Câmara, Niels O.S.

“…Leptin is an adipose‐secreted hormone that plays an important role in both metabolism and immunity. Leptin has been shown to induce Th1‐cell polarization and…”
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Cell death induced by NLRP3–palmitate axis impairs pulmonary damage tolerance and aggravates immunopathology during obesity‐tuberculosis comorbidity by Palma Albornoz, Sandra P, Fraga‐Silva, Thais FC, Carvalho, Renan VH, Rodrigues, Tamara S, Gembre, Ana Flávia, Oliveira, Rômulo Silva, Souza, Fernanda Mesquita, Corrêa, Giseli Furlan, Ramalho, Leandra NZ, Carlos, Daniela, Almeida, Danilo C, Câmara, Niels OS, Zamboni, Dario S, Takahashi, Viviani Nardini, Sorgi, Carlos A, Faccioli, Lucia H, Medeiros, Alexandra I, Costa, Diego Luís, Bonato, Vânia LD

“…A low‐grade and persistent inflammation, which is the hallmark of obesity, requires the participation of NLRP3 and cell death. During Mycobacterium…”
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Apolipoprotein A-I mimetic peptide 4F attenuates kidney injury, heart injury, and endothelial dysfunction in sepsis by Moreira, Roberto S, Irigoyen, Maria, Sanches, Talita R, Volpini, Rildo A, Camara, Niels O S, Malheiros, Denise M, Shimizu, Maria H M, Seguro, Antonio C, Andrade, Lucia

“…Kidney injury, heart injury, and cytokine-induced vascular hyperpermeability are associated with high rates of morbidity and mortality in sepsis. Although the…”
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Hyperglycemia reduces integrin subunits alpha v and alpha 5 on the surface of dermal fibroblasts contributing to deficient migration by Almeida, Maira Estanislau S., Monteiro, Kelly S., Kato, Ellen E., Sampaio, Sandra C., Braga, Tarcio T., Câmara, Niels O. S., Lamers, Marcelo L., Santos, Marinilce F.

“…Deficient wound healing is a common multifactorial complication in diabetic patients, but the cellular and molecular mechanisms involved are poorly defined. In…”
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The lack of PI3Kγ favors M1 macrophage polarization and does not prevent kidney diseases progression by Amano, Mariane T., Castoldi, Angela, Andrade-Oliveira, Vinicius, Latancia, Marcela T., Terra, Fernanda F., Correa-Costa, Matheus, Breda, Cristiane N.S., Felizardo, Raphael J.F., Pereira, Welbert O., da Silva, Marina B., Miyagi, Mariana Y.S., Aguiar, Cristhiane F., Hiyane, Meire I., Silva, João S., Moura, Ivan C., Camara, Niels O.S.

“…Acute kidney injury (AKI) and chronic kidney disease (CKD) are major concerns in worldwide public health, and their pathophysiology involves immune cells…”
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Acute lung injury is reduced by the alpha 7nAChR agonist PNU-282987 through changes in the macrophage profile by Pinheiro, Nathalia M, Santana, Fernanda PR, Almeida, Rafael Ribeiro, Guerreiro, Marina, Martins, Milton A, Caperuto, Luciana C, Camara, Niels OS, Wensing, Lislaine A, Prado, Vaania F, Tibaaerio, Iolanda FLC, Prado, Marco Antaaeonio M, Prado, Carla M

“…Nicotinic alpha -7 acetylcholine receptor (nAChR alpha 7) is a critical regulator of cholinergic anti-inflammatory actions in several diseases, including acute…”
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MATE-1 modulation by kinin B1 receptor enhances cisplatin efflux from renal cells by Estrela, Gabriel R., Wasinski, Frederick, Felizardo, Raphael J. F., Souza, Laura L., Câmara, Niels O. S., Bader, Michael, Araujo, Ronaldo C.

“…Cisplatin is a drug widely used in chemotherapy that frequently causes severe renal dysfunction. Organic transporters have an important role to control the…”
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Kinin B1 receptor deficiency attenuates cisplatin-induced acute kidney injury by modulating immune cell migration by Estrela, Gabriel R., Wasinski, Frederick, Almeida, Danilo C., Amano, Mariane T., Castoldi, Angela, Dias, Carolina C., Malheiros, Denise M. A. C., Almeida, Sandro S., Paredes-Gamero, Edgar J., Pesquero, João B., Barros, Carlos C., Câmara, Niels O. S., Araújo, Ronaldo C.

“…Cisplatin is a chemotherapeutic agent that causes severe renal dysfunction. The kinin B1 receptor has been associated with the migration of immune cells to…”
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Invariant natural killer T cell agonist modulates experimental focal and segmental glomerulosclerosis by Pereira, Rafael L, Reis, Vanessa O, Semedo, Patricia, Buscariollo, Bruna N, Donizetti-Oliveira, Cassiano, Cenedeze, Marcos A, Soares, Maria Fernanda, Pacheco-Silva, Alvaro, Savage, Paul B, Câmara, Niels O S, Keller, Alexandre C

“…A growing body of evidence demonstrates a correlation between Th2 cytokines and the development of focal and segmental glomerulosclerosis (FSGS). Therefore, we…”
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The emergence of cytomegalovirus resistance to ganciclovir therapy in kidney transplant recipients by Nogueira, Eliana, Ozaki, Kikumi S., Tomiyama, Helena, Granato, Celso F.H., Camara, Niels O.S., Silva, Alvaro Pacheco e

“…Transplant recipients that have not been previously exposed to the cytomegalovirus (CMV) are highly susceptible to viral diseases while under immunosuppression…”
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Emerging roles for eicosanoids in renal diseases by Câmara, Niels OS, Martins, Joilson O, Landgraf, Richardt G, Jancar, Sonia

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Distinct effects of CD86-mediated costimulation on resting versus activated human CD4 super(+) T cells by Rogers, Nicola J, Game, David S, Camara, Niels OS, Jackson, Ian M, Lombardi, Giovanna, Lechler, Robert I

“…CD80 and CD86 are important in the initiation of T cell immunity. Although their costimulatory function has long been appreciated, it remains unclear whether…”
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Tim-3 expression in human kidney allografts by Ponciano, Viviane C, Renesto, Paulo G, Nogueira, Eliana, Rangel, Érika B, Cenedeze, Marcos A, Franco, Marcello F, Câmara, Niels O.S, Pacheco-Silva, Alvaro

“…Abstract Background Tim-3 was recently described as a Th1-specific molecule, participating in the regulation of immune responses and in the induction of…”
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Activation of platelet-activating factor receptor exacerbates renal inflammation and promotes fibrosis by Correa-Costa, Matheus, Andrade-Oliveira, Vinicius, Braga, Tarcio T, Castoldi, Angela, Aguiar, Cristhiane F, Origassa, Clarice ST, Rodas, Andrea CD, Hiyane, Meire I, Malheiros, Denise MAC, Rios, Francisco JO, Jancar, Sonia, Câmara, Niels OS

“…Platelet-activating factor (PAF) is a lipid mediator with important pro-inflammatory effects, being synthesized by several cell types including kidney cells…”
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Hepatocellular carcinoma and food contamination: aflatoxins and ochratoxin A as a great prompter by Felizardo, Raphael J F, Câmara, Niels O S

“…Prolonged exposure to mycotoxins in the diet is related to cancer, among other diseases. Hepatocellular carcinoma (HCC) accounts for 70%-90% of primary liver…”
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Emerging roles for eicosanoids in renal diseases by Câmara, Niels OS, Martins, Joilson O, Landgraf, Richardt G, Jancar, Sonia

“…PURPOSE OF REVIEWEicosanoids are products of arachidonic acid metabolism which have important roles in renal homeostasis and disease. In recent years the…”
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Mesenchymal stem cells prevent the blood pressure increase in renovascular hypertension by Oliveira‐Sales, Elizabeth B, Maquigussa, Edgar, Semedo, Patricia, Câmara, Niels OS, Bergamaschi, Cassia T, Boim, Mirian A, Campos, Ruy R

“…The mechanisms responsible for development of renovascular hypertension (2K‐1C) are still on debate and remain undefined; and thus, alternative therapies are…”
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In search of mechanisms associated with mesenchymal stem cell-based therapies for acute kidney injury by de Almeida, Danilo C, Donizetti-Oliveira, Cassiano, Barbosa-Costa, Priscilla, Origassa, Clarice St, Câmara, Niels Os

“…Acute kidney injury (AKI) is classically described as a rapid loss of kidney function. AKI affects more than 15% of all hospital admissions and is associated…”
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Adipokines as Drug Targets in Diabetes and Underlying Disturbances by Andrade-Oliveira, Vinícius, Moraes-Vieira, Pedro M., Camara, Niels Olsen Saraiva

“…Diabetes and obesity are worldwide health problems. White fat dynamically participates in hormonal and inflammatory regulation. White adipose tissue is…”
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